Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   V6U69_RS07300 Genome accession   NZ_CP145867
Coordinates   1593184..1594410 (-) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain KSS10     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1588184..1599410
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U69_RS07270 (V6U69_07270) plsY 1588529..1589170 (+) 642 WP_013990943.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
  V6U69_RS07275 (V6U69_07275) - 1589288..1589665 (-) 378 WP_002885939.1 helix-hairpin-helix domain-containing protein -
  V6U69_RS07280 (V6U69_07280) - 1589740..1589994 (-) 255 WP_002886199.1 DUF1912 family protein -
  V6U69_RS07285 (V6U69_07285) mmuM 1590107..1591057 (-) 951 WP_002885890.1 homocysteine S-methyltransferase -
  V6U69_RS07290 (V6U69_07290) - 1591069..1592445 (-) 1377 WP_080610350.1 amino acid permease -
  V6U69_RS07295 (V6U69_07295) yihA 1592575..1593174 (-) 600 WP_002885996.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  V6U69_RS07300 (V6U69_07300) clpX 1593184..1594410 (-) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  V6U69_RS07305 (V6U69_07305) - 1594428..1594598 (-) 171 WP_002886174.1 hypothetical protein -
  V6U69_RS07310 (V6U69_07310) - 1594603..1595106 (-) 504 WP_410533537.1 dihydrofolate reductase -
  V6U69_RS07315 (V6U69_07315) - 1595215..1596075 (-) 861 WP_410533539.1 thymidylate synthase -
  V6U69_RS07320 (V6U69_07320) - 1596537..1597703 (+) 1167 WP_410533541.1 hydroxymethylglutaryl-CoA synthase -
  V6U69_RS07325 (V6U69_07325) - 1597705..1598979 (+) 1275 WP_410533543.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=940794 V6U69_RS07300 WP_002890340.1 1593184..1594410(-) (clpX) [Streptococcus salivarius strain KSS10]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=940794 V6U69_RS07300 WP_002890340.1 1593184..1594410(-) (clpX) [Streptococcus salivarius strain KSS10]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATCGC
TGGGAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCTGAAACACCAAAGCCAAAAGAACTTTTGGATATTTTGAACAACTATGTCGTGGGGCAAGACCGTGCT
AAACGTGCCTTGGCGGTAGCTGTTTACAACCACTATAAACGTATCAATTTCACAGAAAGTCGTGAAGACAATGATGTGGA
TTTGCAAAAATCAAATATTCTCATGATTGGACCAACTGGTTCAGGGAAGACTTTCTTGGCTCAGACCTTGGCTCGTAGCT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCAGGTTATGTGGGTGAGGACGTGGAAAATATCCTC
CTCAAACTGATTCAAGCGGCAGACTTCAATATTGAACGTGCGGAACGTGGGATCATCTATGTCGACGAGATTGATAAGAT
TGCTAAAAAAGGTGAAAACGTATCAATCACTCGTGACGTTTCTGGTGAAGGGGTTCAACAAGCCCTCTTGAAGATTATCG
AAGGAACAGTAGCTAGCGTTCCACCTCAAGGTGGCCGTAAACACCCTAACCAAGAGATGATTCAAATTGATACGAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCTATTGATGATGACTCATCATACATGCAGGAAATTGTGGCTGAAGATATTCAAAAATTCGGTC
TTATCCCTGAGTTTATCGGACGTTTGCCAGTCCTTGCTGCCCTGGAACAGTTAACGGTGGACGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTATCAAACCCTCTTGTCTTATGATGGAGTTGAACTTGAGTTTGACCAAGA
TGCTCTTGAAGCTATTGCAAGTAAGGCAATCGAACGTAAGACTGGTGCACGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTCATGTTTGAAATTCCTAGCCAGGAAGATGTGACTAAGGTTCGTATTACCAAAGAAGCCGTTGACGGTACA
GCTGCTCCAGTTTTGGAAACAGCGTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566