Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   V6U68_RS02995 Genome accession   NZ_CP145866
Coordinates   597818..599044 (+) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain KSS9     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 592818..604044
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U68_RS02970 (V6U68_02965) - 593251..594522 (-) 1272 WP_410531901.1 hydroxymethylglutaryl-CoA reductase, degradative -
  V6U68_RS02975 (V6U68_02970) - 594524..595690 (-) 1167 WP_410531902.1 hydroxymethylglutaryl-CoA synthase -
  V6U68_RS02980 (V6U68_02975) - 596153..597013 (+) 861 WP_410531903.1 thymidylate synthase -
  V6U68_RS02985 (V6U68_02980) - 597122..597625 (+) 504 WP_410531904.1 dihydrofolate reductase -
  V6U68_RS02990 (V6U68_02985) - 597630..597800 (+) 171 WP_002886174.1 hypothetical protein -
  V6U68_RS02995 (V6U68_02990) clpX 597818..599044 (+) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  V6U68_RS03000 (V6U68_02995) yihA 599054..599653 (+) 600 WP_002885996.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  V6U68_RS03005 (V6U68_03000) mmuM 599741..600691 (+) 951 WP_070839780.1 homocysteine S-methyltransferase -
  V6U68_RS03010 (V6U68_03005) - 600804..601058 (+) 255 WP_002886199.1 DUF1912 family protein -
  V6U68_RS03015 (V6U68_03010) - 601133..601528 (+) 396 WP_410531906.1 helix-hairpin-helix domain-containing protein -
  V6U68_RS03020 (V6U68_03015) plsY 601645..602286 (-) 642 WP_145516351.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=940708 V6U68_RS02995 WP_002890340.1 597818..599044(+) (clpX) [Streptococcus salivarius strain KSS9]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=940708 V6U68_RS02995 WP_002890340.1 597818..599044(+) (clpX) [Streptococcus salivarius strain KSS9]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATCGC
TGGGAATGGCGTCTTTATCTGTAACGAATGTGTGGCCCTGTCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCTGAAACTCCGAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAGGACCGTGCC
AAACGTGCCTTGGCGGTAGCTGTTTACAATCACTATAAACGTATCAATTTCACAGAAAGTCGTGAAGACAATGATGTGGA
TTTGCAAAAATCAAATATTCTCATGATTGGACCAACTGGTTCAGGGAAGACTTTCTTGGCTCAGACCTTGGCTCGTAGCT
TGAATGTTCCATTTGCGATTGCGGATGCAACATCATTGACAGAGGCAGGTTATGTGGGTGAGGACGTGGAAAATATCCTC
CTCAAACTGATTCAAGCGGCAGACTTCAATATCGAACGTGCGGAACGTGGTATCATCTATGTTGACGAGATTGATAAGAT
TGCTAAAAAGGGTGAAAATGTATCAATCACTCGTGACGTTTCTGGTGAAGGGGTTCAACAAGCTCTCTTGAAGATTATCG
AAGGAACAGTAGCCAGCGTTCCCCCTCAAGGTGGTCGTAAACACCCTAACCAAGAGATGATTCAAATTGATACTAAGAAT
ATTCTCTTTATCGTTGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCAATTGATGATGACTCATCATACATGCAAGAAATTGTGGCTGAAGATATTCAAAAATTCGGTC
TTATCCCTGAGTTTATCGGACGTTTGCCAGTCCTTGCGGCCCTTGAACAGTTAACGGTTGACGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTGGAGTTTGACCAGGA
TGCTCTTGAAGCTATTGCAAGTAAGGCAATTGAACGTAAGACCGGTGCGCGTGGCCTTCGCTCTATCATTGAGGAAGTCA
TGATGGATGTCATGTTTGAGATTCCGAGTCAGGAAGATGTTACTAAGGTTCGTATTACAAAAGAAGCCGTTGACGGCACA
GCTGCTCCAGTTTTGGAAACAGCATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566