Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   V6U68_RS01740 Genome accession   NZ_CP145866
Coordinates   330538..331857 (+) Length   439 a.a.
NCBI ID   WP_061652495.1    Uniprot ID   A0AA45CTZ0
Organism   Streptococcus salivarius strain KSS9     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 325538..336857
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U68_RS01715 (V6U68_01710) - 326412..327176 (+) 765 WP_021143582.1 ABC transporter ATP-binding protein -
  V6U68_RS01720 (V6U68_01715) - 327176..327886 (+) 711 WP_002883761.1 ABC transporter ATP-binding protein -
  V6U68_RS01725 (V6U68_01720) - 328021..328680 (+) 660 WP_037600377.1 CBS and ACT domain-containing protein -
  V6U68_RS01730 (V6U68_01725) cysK 328829..329755 (-) 927 WP_061652497.1 cysteine synthase A -
  V6U68_RS01735 (V6U68_01730) - 329857..330483 (-) 627 WP_061652496.1 YigZ family protein -
  V6U68_RS01740 (V6U68_01735) comFA/cflA 330538..331857 (+) 1320 WP_061652495.1 DEAD/DEAH box helicase Machinery gene
  V6U68_RS01745 (V6U68_01740) - 331838..332500 (+) 663 WP_156246370.1 ComF family protein -
  V6U68_RS01750 (V6U68_01745) hpf 332579..333127 (+) 549 WP_002883786.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50699.95 Da        Isoelectric Point: 9.7017

>NTDB_id=940699 V6U68_RS01740 WP_061652495.1 330538..331857(+) (comFA/cflA) [Streptococcus salivarius strain KSS9]
MVPKEYYGRLFTKEQLPVNYHPEALTLESMIKVDKQLRCKRCYSWIEEDWQLPGGQYYCRACIVFGRNQEGKELYYFPSK
TSEIEFPVLKWFGELTPYQAEISEKLLRTYQKQKDSLVHAVTGAGKTEMIYNIVAYVLENKGHVAIASPRVDVCRELFLR
MKRDFTCSISLLHAEGEPYDGSPLVIATTHQLLKFYQSFDLVIVDEVDAYPFVGNVMLNHAVEQAKTETGRFIYLTATST
LSLEEQVRLGTLEKHHLARRFHGNPLVLPKFFWQGRLQKSLTRGKLPRPLLYQIKKQRKSKFPLLIFFPNIAIGEKFTSI
LQKYLPDEKMAFVSSKSEKRSTIVEKFRKKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPDR
PTGKLYFFHEGLSKSMLRCREEIKVMNKKGGFNNEVSAM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=940699 V6U68_RS01740 WP_061652495.1 330538..331857(+) (comFA/cflA) [Streptococcus salivarius strain KSS9]
ATGGTACCTAAAGAATATTATGGACGACTATTTACGAAAGAGCAGTTGCCAGTGAACTATCACCCAGAGGCTTTAACATT
AGAAAGTATGATAAAGGTCGATAAACAACTTAGATGTAAAAGATGTTACAGTTGGATAGAGGAAGATTGGCAATTACCGG
GAGGTCAGTATTATTGTAGAGCATGTATTGTCTTTGGTAGAAACCAAGAAGGAAAAGAACTTTATTATTTTCCTTCCAAA
ACATCAGAAATTGAATTTCCTGTTTTGAAGTGGTTTGGAGAACTGACTCCCTATCAAGCTGAGATCTCAGAGAAACTTTT
GAGAACTTATCAAAAACAGAAAGATAGTCTCGTACATGCTGTGACCGGTGCTGGTAAGACAGAAATGATTTATAACATCG
TTGCCTATGTTCTGGAAAATAAAGGTCATGTAGCTATCGCAAGTCCTAGGGTTGATGTTTGTCGAGAATTATTTCTACGT
ATGAAGAGGGATTTTACTTGTAGTATTTCCCTGCTTCATGCTGAGGGTGAACCATATGATGGTAGTCCGCTTGTAATAGC
TACCACACATCAACTACTAAAGTTTTACCAGAGTTTTGACTTAGTTATTGTAGATGAAGTAGATGCATATCCTTTTGTAG
GCAATGTCATGTTAAATCATGCTGTAGAACAGGCGAAGACCGAAACCGGTCGATTTATTTACTTAACAGCGACTTCAACA
TTATCTTTAGAAGAGCAAGTTCGACTTGGGACTTTAGAAAAGCATCACCTTGCTAGACGTTTCCATGGAAATCCTTTAGT
ACTTCCTAAATTCTTCTGGCAGGGCAGATTACAAAAATCTCTGACAAGAGGCAAGCTTCCAAGACCTCTTCTTTATCAGA
TTAAAAAGCAACGTAAATCAAAATTTCCTCTATTAATCTTCTTTCCAAATATAGCGATAGGTGAAAAGTTTACAAGTATT
CTACAAAAATATCTTCCAGATGAAAAAATGGCCTTTGTTTCCTCAAAAAGCGAGAAGCGTTCAACTATCGTAGAGAAGTT
CCGAAAAAAAGAACTGTCTATCTTAGTGACAACAACTATCCTCGAACGTGGTGTAACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATATACTAGTTCGAGTCTTATTCAGATTGGAGGAAGAGTTGGAAGATCACCAGATAGA
CCGACAGGAAAGCTTTATTTCTTTCATGAAGGACTATCCAAATCAATGCTTCGGTGTCGAGAAGAGATAAAGGTTATGAA
TAAAAAAGGAGGGTTTAACAATGAAGTGTCTGCTATGTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-170)

Helicase conserved C-terminal domain (Helicase_C)

(290-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

55.22

98.178

0.542
  comFA/cflA Streptococcus pneumoniae D39

55.22

98.178

0.542
  comFA/cflA Streptococcus pneumoniae R6

55.22

98.178

0.542
  comFA/cflA Streptococcus pneumoniae TIGR4

55.22

98.178

0.542
  comFA/cflA Streptococcus mitis NCTC 12261

54.378

98.861

0.538
  comFA/cflA Streptococcus mitis SK321

53.828

98.178

0.528
  comFA Lactococcus lactis subsp. cremoris KW2

46.667

95.672

0.446
  comFA Latilactobacillus sakei subsp. sakei 23K

37.471

99.089

0.371