Detailed information NTG0940599

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: V6U66_RS08815
• Genome accession: NZ_CP145864
• Coordinates: 1894406..1895482 (-)
• Length: 358 a.a.
• NCBI ID: WP_002884703.1
• Uniprot ID: A0A1W5ZBL0
• Organism: Streptococcus salivarius strain KSS7
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1889406..1900482

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U66_RS08790 (V6U66_08780)	-	1889553..1890335 (+)	783	WP_118172067.1	ABC transporter ATP-binding protein	-
V6U66_RS08795 (V6U66_08785)	-	1890519..1892585 (-)	2067	WP_221739266.1	cation:proton antiporter	-
V6U66_RS08800 (V6U66_08790)	-	1892594..1892836 (-)	243	WP_014634967.1	hypothetical protein	-
V6U66_RS08805 (V6U66_08795)	-	1892833..1893381 (-)	549	WP_221739267.1	tRNA (mnm(5)s(2)U34)-methyltransferase	-
V6U66_RS08810 (V6U66_08800)	-	1893378..1894322 (-)	945	WP_221739268.1	TIGR01212 family radical SAM protein	-
V6U66_RS08815 (V6U66_08805)	sepM	1894406..1895482 (-)	1077	WP_002884703.1	SepM family pheromone-processing serine protease	Regulator
V6U66_RS08820 (V6U66_08810)	coaD	1895460..1895957 (-)	498	WP_014632676.1	pantetheine-phosphate adenylyltransferase	-
V6U66_RS08825 (V6U66_08815)	rsmD	1895990..1896538 (-)	549	WP_231910681.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
V6U66_RS08830 (V6U66_08820)	trxB	1896678..1897598 (-)	921	WP_014632674.1	thioredoxin-disulfide reductase	-
V6U66_RS08835 (V6U66_08825)	-	1897664..1897888 (-)	225	WP_002884393.1	DUF4059 family protein	-
V6U66_RS08840 (V6U66_08830)	-	1898100..1898843 (-)	744	WP_014632672.1	amino acid ABC transporter ATP-binding protein	-
V6U66_RS08845 (V6U66_08835)	-	1898843..1899589 (-)	747	WP_096832659.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 38988.67 Da
• Isoelectric Point: 9.2472

>NTDB_id=940599 V6U66_RS08815 WP_002884703.1 1894406..1895482(-) (sepM) [Streptococcus salivarius strain KSS7]
MANKNESKSLLGKIWRIKWWLLSIFTVLFLLFALFFPLNNYYVELPGGAFDTKEVLTVDKKADDSKGSYNFVAVAQTKAT
LALMLYAQLNDFAKLQTAEEATGNYSDEDFMRINQFYMETSQNQAIYQGLTLAGKEASLEYMGVYVLQVADDSSFKGVLN
IADTVTAVNGKTFDNSADLIKYVQGLKLGSKVKVTYTTDDKEKTATGKIIKIANGKNGIGIGLTDHTEVKSPENVKFKLD
GVGGPSAGLMFTLAIYDQVSGQDLKAGRKIAGTGTIEKDGSVGDIGGAYLKVKSAADSGADIFFVPNNPVTKEMKKADPD
AKTNYQEAKEAAKKLGTKMKIVPVKTAQEAIDYLKKTK

Nucleotide

• Length: 1077 bp

>NTDB_id=940599 V6U66_RS08815 WP_002884703.1 1894406..1895482(-) (sepM) [Streptococcus salivarius strain KSS7]
GTGGCAAACAAGAACGAATCTAAATCACTATTAGGGAAAATTTGGCGGATTAAGTGGTGGTTGTTAAGTATTTTTACGGT
ACTTTTCCTCCTATTTGCCCTCTTTTTCCCGCTAAATAATTATTATGTTGAGCTTCCGGGTGGTGCTTTTGATACTAAGG
AAGTCTTGACTGTAGACAAGAAAGCTGATGATTCAAAAGGATCCTACAATTTTGTGGCAGTGGCCCAAACCAAGGCGACT
TTAGCCTTGATGCTCTATGCTCAGCTTAATGATTTTGCAAAGCTTCAAACAGCTGAAGAGGCAACTGGGAATTACTCTGA
TGAAGATTTCATGCGTATCAACCAATTTTACATGGAGACTTCCCAAAACCAAGCGATTTATCAGGGCTTGACTCTGGCCG
GTAAGGAGGCTAGCTTGGAGTATATGGGTGTCTATGTGCTTCAGGTGGCTGATGATTCTAGCTTCAAGGGTGTCCTCAAT
ATTGCGGATACGGTGACAGCTGTCAATGGCAAGACCTTTGATAATTCTGCTGACTTGATTAAATACGTTCAAGGACTTAA
GCTGGGTTCAAAAGTCAAGGTCACTTATACGACAGATGACAAAGAAAAGACTGCCACTGGTAAGATTATCAAGATTGCCA
ATGGTAAAAATGGTATTGGTATCGGTTTGACAGATCATACCGAGGTTAAGAGTCCTGAAAATGTGAAGTTTAAACTTGAT
GGCGTTGGCGGACCAAGTGCGGGTCTTATGTTTACCCTAGCTATTTACGATCAGGTATCTGGTCAAGACCTCAAGGCTGG
CCGTAAGATTGCTGGAACAGGAACCATTGAAAAGGATGGTTCGGTCGGTGATATCGGTGGTGCCTACCTCAAGGTGAAAT
CAGCGGCTGATAGTGGTGCAGACATTTTCTTCGTGCCAAATAATCCAGTAACCAAGGAAATGAAAAAGGCTGATCCGGAT
GCCAAAACCAACTATCAAGAGGCCAAGGAAGCTGCCAAGAAACTGGGAACCAAGATGAAAATCGTCCCTGTTAAAACAGC
TCAAGAAGCCATTGATTATTTGAAAAAGACTAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (142-206)

3D structure

• AlphaFold DB: A0A1W5ZBL0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	65.396	95.251	0.623