Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   V6U66_RS07630 Genome accession   NZ_CP145864
Coordinates   1648487..1649713 (-) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain KSS7     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1643487..1654713
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U66_RS07600 (V6U66_07590) plsY 1643829..1644470 (+) 642 WP_014633423.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
  V6U66_RS07605 (V6U66_07595) - 1644588..1644965 (-) 378 WP_002885939.1 helix-hairpin-helix domain-containing protein -
  V6U66_RS07610 (V6U66_07600) - 1645040..1645294 (-) 255 WP_002886199.1 DUF1912 family protein -
  V6U66_RS07615 (V6U66_07605) mmuM 1645407..1646357 (-) 951 WP_014633424.1 homocysteine S-methyltransferase -
  V6U66_RS07620 (V6U66_07610) - 1646369..1647745 (-) 1377 WP_061652253.1 amino acid permease -
  V6U66_RS07625 (V6U66_07615) yihA 1647878..1648477 (-) 600 WP_048676032.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  V6U66_RS07630 (V6U66_07620) clpX 1648487..1649713 (-) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  V6U66_RS07635 (V6U66_07625) - 1649731..1649901 (-) 171 WP_002886174.1 hypothetical protein -
  V6U66_RS07640 (V6U66_07630) - 1649906..1650409 (-) 504 WP_002885904.1 dihydrofolate reductase -
  V6U66_RS07645 (V6U66_07635) - 1650518..1651378 (-) 861 WP_004182958.1 thymidylate synthase -
  V6U66_RS07650 (V6U66_07640) - 1651679..1652845 (+) 1167 WP_014633427.1 hydroxymethylglutaryl-CoA synthase -
  V6U66_RS07655 (V6U66_07645) - 1652847..1654118 (+) 1272 WP_004182960.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=940592 V6U66_RS07630 WP_002890340.1 1648487..1649713(-) (clpX) [Streptococcus salivarius strain KSS7]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=940592 V6U66_RS07630 WP_002890340.1 1648487..1649713(-) (clpX) [Streptococcus salivarius strain KSS7]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATCGC
TGGGAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCTGAAACTCCGAAGCCAAAAGAACTTTTGGATATTTTGAACAACTATGTCGTGGGGCAAGACCGTGCT
AAACGTGCTTTGGCGGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGACAATGATGTGGA
TTTGCAAAAATCAAATATTCTCATGATTGGACCAACCGGTTCAGGGAAGACTTTCTTGGCTCAGACCTTGGCTCGAAGCT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCTGGTTATGTGGGTGAGGACGTGGAAAATATCCTC
CTCAAACTGATCCAAGCGGCAGACTTCAATATTGAACGTGCGGAACGTGGAATCATCTATGTCGACGAGATTGATAAGAT
TGCTAAAAAAGGTGAAAACGTATCAATCACTCGTGACGTTTCTGGTGAAGGGGTTCAACAAGCCCTCTTGAAGATTATCG
AAGGAACAGTAGCTAGCGTTCCACCTCAAGGTGGTCGTAAACACCCTAACCAAGAGATGATTCAAATTGATACGAAGAAT
ATTCTTTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCTATTGATGATGACTCATCATACATGCAGGAAATTGTGGCTGAAGATATCCAAAAATTTGGTC
TTATCCCTGAGTTTATCGGACGTTTGCCAGTCCTTGCGGCCCTTGAACAGTTAACGGTGGACGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCTCTTGAAGCTATTGCAAGTAAGGCGATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTTA
TGATGGATGTCATGTTTGAAATTCCTAGCCAGGAAGATGTGACTAAGGTTCGTATTACCAAAGAAGCTGTTGACGGTACA
GCTGCTCCAGTTTTGGAAACAGCGTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566