Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   V6U64_RS08370 Genome accession   NZ_CP145862
Coordinates   1825487..1826806 (-) Length   439 a.a.
NCBI ID   WP_139724577.1    Uniprot ID   A0AAX2V0S9
Organism   Streptococcus salivarius strain KSS4     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1820487..1831806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U64_RS08360 (V6U64_08360) hpf 1824217..1824765 (-) 549 WP_002883786.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  V6U64_RS08365 (V6U64_08365) - 1824844..1825506 (-) 663 WP_041826648.1 ComF family protein -
  V6U64_RS08370 (V6U64_08370) comFA/cflA 1825487..1826806 (-) 1320 WP_139724577.1 DEAD/DEAH box helicase Machinery gene
  V6U64_RS08375 (V6U64_08375) - 1826861..1827487 (+) 627 WP_014633929.1 YigZ family protein -
  V6U64_RS08380 (V6U64_08380) cysK 1827589..1828515 (+) 927 WP_002883742.1 cysteine synthase A -
  V6U64_RS08385 (V6U64_08385) - 1828699..1829358 (-) 660 WP_064520716.1 CBS and ACT domain-containing protein -
  V6U64_RS08390 (V6U64_08390) - 1829493..1830203 (-) 711 WP_014633927.1 ABC transporter ATP-binding protein -
  V6U64_RS08395 (V6U64_08395) - 1830203..1830967 (-) 765 WP_002883723.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50612.64 Da        Isoelectric Point: 9.0241

>NTDB_id=940464 V6U64_RS08370 WP_139724577.1 1825487..1826806(-) (comFA/cflA) [Streptococcus salivarius strain KSS4]
MVPKEYYGRLFTKEQLPVDYHSEAFTLESMIKVDKQLRCKRCYSQIEEDWQLPGGQYYCRACIVFGRNQEGKELYYFPSK
TSEIEFPVLKWLGELTPYQAEVSEKLLETYQKQKDSLVHAVTGAGKTEMIYKIVAYVLESKGNVAIASPRVDVCRELFLR
MQRDFTCSISLLHAESEPYDGSPLVIATTHQLLKFYQNFDLVIVDEVDAFPFVGNVMLNHAVEQAKKETGRYIYLTATST
LSLEEQVRLGALEKHHLARRFHGNPLVLPKFCWQGRLQKSLMRGKLPRPLLYQIKKQRKSKFPLLIFFPNIAIGEKFTNI
LQKYLPDEKMAFVSSKSEERSATVEQFREKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPDR
PTGKLYFFHEGLSKSMLRCREEIKVMNKKGGFNNEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=940464 V6U64_RS08370 WP_139724577.1 1825487..1826806(-) (comFA/cflA) [Streptococcus salivarius strain KSS4]
ATGGTACCTAAAGAATATTATGGACGACTATTTACGAAAGAACAGTTGCCAGTGGACTATCACTCAGAGGCTTTTACATT
AGAAAGCATGATAAAGGTCGATAAACAACTTAGATGTAAAAGATGTTACAGTCAGATAGAGGAAGATTGGCAATTACCGG
GAGGTCAGTATTATTGCAGAGCATGTATTGTCTTTGGCAGAAACCAAGAAGGAAAAGAACTTTATTATTTTCCTTCAAAA
ACATCTGAAATTGAATTTCCTGTTTTGAAGTGGTTGGGGGAACTGACTCCCTATCAAGCTGAGGTCTCAGAGAAGCTTTT
AGAAACATATCAAAAACAGAAAGACAGCCTCGTACATGCTGTGACTGGTGCTGGGAAGACTGAGATGATTTATAAAATCG
TTGCCTATGTTCTTGAAAGTAAAGGTAATGTAGCTATCGCAAGTCCTCGGGTTGATGTTTGTCGAGAGTTATTTCTTCGT
ATGCAGAGGGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGAGAGTGAACCATATGATGGTAGTCCGCTTGTAATAGC
TACCACCCATCAACTACTAAAGTTTTACCAGAACTTTGACCTAGTTATCGTTGATGAGGTTGATGCATTCCCTTTTGTAG
GAAATGTCATGTTAAATCATGCTGTGGAGCAGGCAAAGAAGGAAACCGGTCGCTATATTTATTTAACAGCGACTTCTACA
TTATCTTTAGAGGAGCAAGTGCGACTTGGAGCTTTAGAAAAGCATCACCTTGCCAGACGTTTCCATGGAAATCCTTTAGT
ACTTCCTAAATTCTGCTGGCAGGGAAGATTACAAAAATCTCTAATGAGAGGCAAGCTTCCAAGGCCTCTTCTTTATCAGA
TTAAAAAGCAACGTAAATCAAAGTTTCCTCTATTAATCTTTTTCCCAAATATAGCGATAGGTGAAAAGTTTACCAATATT
CTACAAAAATATCTTCCAGATGAAAAAATGGCCTTTGTTTCTTCAAAAAGCGAGGAGCGCTCAGCTACCGTAGAGCAGTT
CCGGGAAAAAGAGTTATCCATCTTAGTGACAACAACTATCCTTGAACGTGGTGTAACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATACACTAGTTCGAGTCTTATTCAGATAGGAGGTCGAGTTGGAAGATCTCCAGATAGA
CCGACAGGGAAGCTTTATTTCTTTCATGAAGGACTATCCAAATCTATGCTTCGTTGTCGAGAAGAAATAAAGGTTATGAA
TAAAAAAGGAGGATTTAACAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(94-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae TIGR4

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae Rx1

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae D39

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae R6

56.381

98.178

0.554
  comFA/cflA Streptococcus mitis NCTC 12261

55.53

98.861

0.549
  comFA/cflA Streptococcus mitis SK321

54.988

98.178

0.54
  comFA Lactococcus lactis subsp. cremoris KW2

45.476

95.672

0.435
  comFA Latilactobacillus sakei subsp. sakei 23K

38.073

99.317

0.378