Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   V6U64_RS07260 Genome accession   NZ_CP145862
Coordinates   1588922..1590148 (-) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain KSS4     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1579121..1588029 1588922..1590148 flank 893


Gene organization within MGE regions


Location: 1579121..1590148
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U64_RS07210 (V6U64_07210) - 1579121..1579669 (-) 549 WP_410536379.1 hypothetical protein -
  V6U64_RS07215 (V6U64_07215) parE 1579825..1581774 (-) 1950 WP_013990942.1 DNA topoisomerase IV subunit B -
  V6U64_RS07220 (V6U64_07220) plsY 1581912..1582553 (+) 642 WP_410536381.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
  V6U64_RS07225 (V6U64_07225) - 1582671..1583048 (-) 378 WP_002885939.1 helix-hairpin-helix domain-containing protein -
  V6U64_RS07230 (V6U64_07230) - 1583123..1583377 (-) 255 WP_002886199.1 DUF1912 family protein -
  V6U64_RS07235 (V6U64_07235) mmuM 1583490..1584440 (-) 951 WP_410536383.1 homocysteine S-methyltransferase -
  V6U64_RS07240 (V6U64_07240) - 1584453..1585829 (-) 1377 WP_410536385.1 amino acid permease -
  V6U64_RS07245 (V6U64_07245) - 1585959..1586069 (-) 111 Protein_1413 YihA family ribosome biogenesis GTP-binding protein -
  V6U64_RS07250 (V6U64_07250) - 1586035..1588029 (-) 1995 WP_410536387.1 retron Ec67 family RNA-directed DNA polymerase/endonuclease -
  V6U64_RS07255 (V6U64_07255) yihA 1588313..1588912 (-) 600 WP_002885996.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  V6U64_RS07260 (V6U64_07260) clpX 1588922..1590148 (-) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=940456 V6U64_RS07260 WP_002890340.1 1588922..1590148(-) (clpX) [Streptococcus salivarius strain KSS4]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=940456 V6U64_RS07260 WP_002890340.1 1588922..1590148(-) (clpX) [Streptococcus salivarius strain KSS4]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATCGC
TGGGAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCTGAAACTCCGAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAGGACCGTGCC
AAACGTGCCTTGGCGGTAGCTGTTTACAATCACTATAAACGTATCAATTTCACAGAAAGTCGTGAAGACAATGATGTGGA
TTTGCAAAAATCAAATATTCTCATGATTGGACCAACTGGTTCAGGGAAGACTTTCTTGGCTCAGACCTTGGCTCGTAGCT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCAGGTTATGTGGGTGAGGACGTGGAAAATATCCTC
CTCAAACTGATTCAAGCGGCAGACTTCAATATTGAACGTGCGGAACGTGGGATCATCTATGTCGACGAGATTGATAAGAT
TGCTAAAAAAGGTGAAAACGTATCAATCACTCGTGACGTTTCTGGTGAAGGGGTTCAACAAGCCCTCTTGAAGATTATCG
AAGGAACAGTAGCTAGCGTTCCACCTCAAGGTGGCCGTAAACACCCTAACCAAGAGATGATTCAAATTGATACGAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCTATTGATGATGACTCATCATACATGCAGGAAATTGTGGCTGAAGATATTCAAAAATTCGGTC
TTATCCCTGAGTTTATCGGACGTTTGCCAGTCCTTGCTGCCCTGGAACAGTTAACGGTGGACGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTACCAAACCCTTTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAAGA
TGCTCTTGAAGCTATTGCAAGTAAGGCGATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTCATGTTTGAAATTCCTAGCCAGGAAGATGTGACTAAGGTTCGTATTACCAAAGAAGCTGTTGACGGTACA
GCTGCTCCAGTTTTGGAAACAGCGTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566