Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   V6U63_RS04545 Genome accession   NZ_CP145861
Coordinates   922464..923807 (+) Length   447 a.a.
NCBI ID   WP_410535408.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS3     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 917464..928807
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U63_RS04515 (V6U63_04510) - 917532..918299 (-) 768 WP_037611663.1 amino acid ABC transporter ATP-binding protein -
  V6U63_RS04520 (V6U63_04515) - 918491..919141 (-) 651 WP_002886253.1 amino acid ABC transporter permease -
  V6U63_RS04525 (V6U63_04520) - 919153..919851 (-) 699 WP_002886251.1 amino acid ABC transporter permease -
  V6U63_RS04530 (V6U63_04525) - 919869..920702 (-) 834 WP_410535406.1 transporter substrate-binding domain-containing protein -
  V6U63_RS04535 (V6U63_04530) - 920712..921479 (-) 768 WP_021145491.1 amino acid ABC transporter ATP-binding protein -
  V6U63_RS04540 (V6U63_04535) vicR 921764..922471 (+) 708 WP_002884978.1 response regulator YycF Regulator
  V6U63_RS04545 (V6U63_04540) vicK 922464..923807 (+) 1344 WP_410535408.1 cell wall metabolism sensor histidine kinase VicK Regulator
  V6U63_RS04550 (V6U63_04545) vicX 923810..924622 (+) 813 WP_013990680.1 MBL fold metallo-hydrolase Regulator
  V6U63_RS04555 (V6U63_04550) - 924681..925040 (+) 360 WP_037611660.1 YbaN family protein -
  V6U63_RS04560 (V6U63_04555) - 925092..926306 (-) 1215 WP_037611659.1 aminoacyltransferase -
  V6U63_RS04565 (V6U63_04560) yidA 926308..927117 (-) 810 WP_002890845.1 sugar-phosphatase -
  V6U63_RS04570 (V6U63_04565) - 927295..928161 (+) 867 WP_145516924.1 GNAT family N-acetyltransferase -
  V6U63_RS04575 (V6U63_04570) - 928244..928630 (+) 387 WP_002884910.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 447 a.a.        Molecular weight: 51058.32 Da        Isoelectric Point: 5.0731

>NTDB_id=940377 V6U63_RS04545 WP_410535408.1 922464..923807(+) (vicK) [Streptococcus salivarius strain KSS3]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDFETATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEME

Nucleotide


Download         Length: 1344 bp        

>NTDB_id=940377 V6U63_RS04545 WP_410535408.1 922464..923807(+) (vicK) [Streptococcus salivarius strain KSS3]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTGGCTTTCTACTTTAT
TTTTCTTGCATATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGGGTCAAGTCCTTAATGGCAGGTA
ACTATAACGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGACGTC
TTTCGTTTGACGCATGAAAATCTGGCCCAGGAAAAAAACCGCTTATCATCAGTCCTCTCTTACATGAGTGATGGGGTTAT
TGCGACTAATCGACGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTTTGAGACAGCGA
CACAGATGTCCATTTTAGATTTATTAGATGGTGAAAATCCCTATACTTATAGTGAATTGCTCTCTAAGACTCCTGAAATT
CATTTGTCACGTCGAGATGCCAACGATGAGTTTGTGACCTTACGTGTTAACTTTGCCCTTATTCGTAAAGAATCAGGTTT
TATCTCAGGTCTGGTTGCTGTTCTTCACGATGCCACTGAGCAGGAAAAAGAAGAGCGTGAACGTCGACTTTTCGTCTCGA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCCTATCTGGAGGCACTTGATGATGGAGCTCTCGATGAA
GAGATTGCACCTAACTTCATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
GTCTCGTATTGACAATAAGAGTACCCAACTTGACGTTGAGATGACCAATTTCACGGCCTTCATGACCTATATCTTGAATC
GTTTTGATCAGATTAAAAGTCAAGAAACCAATACAGGTAAAACTTACGAAATCATTCGAGATTACCCAGTAAACTCAATT
TGGGTAGAGATTGATACAGATAAGATGACCCAGGTCGTGGATAATATTCTTAATAATGCCATTAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGATTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAAGATTTGCCTTTGATTTTCGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCCCAGGGTGGAACGGGTCTA
GGCTTGTCCATTGCCAAAGAGATTATTAAACAACATAAGGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
ATTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGGAGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92.617

0.682
  micB Streptococcus pneumoniae Cp1015

67.667

96.868

0.655