Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   V6U63_RS01775 Genome accession   NZ_CP145861
Coordinates   339597..340916 (+) Length   439 a.a.
NCBI ID   WP_349955341.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS3     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 340897..351162 339597..340916 flank -19


Gene organization within MGE regions


Location: 339597..351162
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U63_RS01775 (V6U63_01780) comFA/cflA 339597..340916 (+) 1320 WP_349955341.1 DEAD/DEAH box helicase Machinery gene
  V6U63_RS01780 (V6U63_01785) - 340897..341559 (+) 663 WP_195187835.1 ComF family protein -
  V6U63_RS01785 (V6U63_01790) hpf 341638..342186 (+) 549 WP_002883786.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  V6U63_RS01840 (V6U63_01845) - 348106..349038 (+) 933 WP_014633932.1 manganese-dependent inorganic pyrophosphatase -
  V6U63_RS01845 (V6U63_01850) - 349093..349752 (+) 660 WP_004181883.1 DUF1803 domain-containing protein -
  V6U63_RS01850 (V6U63_01855) - 349782..350315 (-) 534 WP_002886644.1 DUF402 domain-containing protein -
  V6U63_RS01855 (V6U63_01860) recX 350386..351162 (-) 777 WP_195187607.1 recombination regulator RecX -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50580.61 Da        Isoelectric Point: 8.9447

>NTDB_id=940363 V6U63_RS01775 WP_349955341.1 339597..340916(+) (comFA/cflA) [Streptococcus salivarius strain KSS3]
MVPKEYYGRLFTKEQLPVDYHSEAFTLESMIKVDKQLRCKRCYSQIEEDWQLPGGQYYCRACIVFGRNQEGKELYYFPSK
TSEIEFPVLKWLGELTPYQAEVSEKLLETYQRQKDSLVHAVTGAGKTEMIYKIVAYVLESKGNVAIASPRVDVCRELFLR
MQRDFTCSISLLHAESEPYDGSPLVIATTHQLLKFYQNFDLVIVDEVDAFPFVGNVMLNHAVEQAKKETGRYIYLTATST
LSLEEQVRLGALEKHHLARRFHGNPLVLPKFCWQGRLQKSLMRGKLPRPLLYQIKKQRKSKFPLLIFFPNIAIGEKFTNI
LQKCLPDEKMAFVSSKSEERSATVEQFREKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPDR
PTGKLYFFHEGLSKSMLRCREEIKVMNKKGGFNNEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=940363 V6U63_RS01775 WP_349955341.1 339597..340916(+) (comFA/cflA) [Streptococcus salivarius strain KSS3]
ATGGTACCTAAAGAATATTATGGACGACTATTTACGAAAGAACAGTTGCCAGTGGACTATCACTCAGAGGCTTTTACATT
AGAAAGCATGATAAAGGTCGATAAACAACTTAGATGTAAAAGATGTTACAGTCAGATAGAGGAAGATTGGCAATTACCGG
GAGGTCAGTATTATTGCAGAGCATGTATTGTCTTTGGCAGAAACCAAGAAGGAAAAGAACTTTATTATTTTCCTTCAAAA
ACATCTGAAATTGAATTTCCTGTTTTGAAGTGGTTGGGGGAACTGACTCCCTATCAAGCTGAGGTCTCAGAGAAGCTTTT
AGAAACATATCAAAGACAGAAAGACAGCCTCGTACATGCTGTGACTGGTGCTGGGAAGACTGAGATGATTTATAAAATCG
TTGCCTATGTTCTTGAAAGTAAAGGTAATGTAGCTATCGCAAGTCCTCGGGTTGATGTTTGTCGAGAGTTATTTCTTCGT
ATGCAGAGGGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGAGAGTGAACCATATGATGGTAGTCCGCTTGTAATAGC
TACCACCCATCAACTACTAAAGTTTTACCAGAACTTTGACCTAGTTATCGTTGATGAGGTTGATGCATTCCCTTTTGTAG
GAAATGTCATGTTAAATCATGCTGTGGAGCAGGCAAAGAAGGAAACCGGTCGCTATATTTATTTAACAGCGACTTCTACA
TTATCTTTAGAGGAGCAAGTGCGACTTGGAGCTTTAGAAAAGCATCACCTTGCCAGACGTTTCCATGGAAATCCTTTAGT
ACTTCCTAAATTCTGCTGGCAGGGAAGATTACAAAAATCTCTAATGAGAGGCAAGCTTCCAAGGCCTCTTCTTTATCAGA
TTAAAAAGCAACGTAAATCAAAGTTTCCTCTATTAATCTTTTTCCCAAATATAGCGATAGGTGAAAAGTTTACCAATATT
CTACAAAAATGTCTTCCAGATGAAAAAATGGCCTTTGTTTCTTCAAAAAGCGAGGAGCGCTCAGCTACCGTAGAGCAGTT
CCGGGAAAAAGAGTTATCCATCTTAGTGACAACAACTATCCTTGAACGTGGTGTAACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATACACTAGTTCGAGTCTTATTCAGATAGGAGGTCGAGTTGGAAGATCCCCAGATAGA
CCGACAGGGAAGCTTTATTTCTTTCATGAAGGACTATCCAAATCTATGCTTCGTTGTCGAGAAGAAATAAAGGTTATGAA
TAAAAAAGGAGGATTTAACAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-170)

Helicase conserved C-terminal domain (Helicase_C)

(290-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

56.148

98.178

0.551
  comFA/cflA Streptococcus pneumoniae D39

56.148

98.178

0.551
  comFA/cflA Streptococcus pneumoniae R6

56.148

98.178

0.551
  comFA/cflA Streptococcus pneumoniae TIGR4

56.148

98.178

0.551
  comFA/cflA Streptococcus mitis NCTC 12261

55.3

98.861

0.547
  comFA/cflA Streptococcus mitis SK321

54.756

98.178

0.538
  comFA Lactococcus lactis subsp. cremoris KW2

45.476

95.672

0.435
  comFA Latilactobacillus sakei subsp. sakei 23K

38.073

99.317

0.378