Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   V6T26_RS07250 Genome accession   NZ_CP145858
Coordinates   1570600..1571826 (-) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain KSS11     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1565600..1576826
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6T26_RS07220 (V6T26_07220) plsY 1565957..1566598 (+) 642 WP_073689886.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
  V6T26_RS07225 (V6T26_07225) - 1566715..1567083 (-) 369 WP_201042695.1 helix-hairpin-helix domain-containing protein -
  V6T26_RS07230 (V6T26_07230) - 1567158..1567412 (-) 255 WP_002886199.1 DUF1912 family protein -
  V6T26_RS07235 (V6T26_07235) mmuM 1567525..1568475 (-) 951 WP_201059374.1 homocysteine S-methyltransferase -
  V6T26_RS07240 (V6T26_07240) - 1568487..1569863 (-) 1377 Protein_1411 amino acid permease -
  V6T26_RS07245 (V6T26_07245) yihA 1569991..1570590 (-) 600 WP_002885996.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  V6T26_RS07250 (V6T26_07250) clpX 1570600..1571826 (-) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  V6T26_RS07255 (V6T26_07255) - 1571844..1572014 (-) 171 WP_002886174.1 hypothetical protein -
  V6T26_RS07260 (V6T26_07260) - 1572019..1572522 (-) 504 WP_347092976.1 dihydrofolate reductase -
  V6T26_RS07265 (V6T26_07265) - 1572631..1573491 (-) 861 WP_201041597.1 thymidylate synthase -
  V6T26_RS07270 (V6T26_07270) - 1573964..1575130 (+) 1167 WP_201041598.1 hydroxymethylglutaryl-CoA synthase -
  V6T26_RS07275 (V6T26_07275) - 1575132..1576403 (+) 1272 WP_110980889.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=940257 V6T26_RS07250 WP_002890340.1 1570600..1571826(-) (clpX) [Streptococcus salivarius strain KSS11]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=940257 V6T26_RS07250 WP_002890340.1 1570600..1571826(-) (clpX) [Streptococcus salivarius strain KSS11]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATCGC
TGGGAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCTGAAACTCCGAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAGGACCGTGCC
AAACGTGCCTTGGCGGTAGCTGTTTACAATCACTATAAACGTATCAATTTCACAGAAAGTCGTGAAGACAATGATGTGGA
TTTGCAAAAATCAAATATTCTCATGATTGGACCAACTGGTTCAGGGAAGACTTTCTTGGCTCAGACCTTGGCTCGTAGCT
TGAATGTTCCATTTGCGATTGCGGATGCAACATCATTGACAGAGGCAGGTTATGTGGGTGAGGACGTGGAAAATATCCTC
CTCAAACTGATCCAAGCGGCAGACTTCAATATCGAACGTGCGGAACGTGGTATCATTTATGTTGACGAGATTGATAAGAT
TGCTAAAAAGGGTGAAAATGTATCAATCACTCGTGACGTTTCTGGTGAGGGGGTTCAACAAGCTCTCTTGAAGATTATCG
AAGGAACAGTAGCTAGCGTTCCCCCTCAAGGTGGTCGTAAACACCCTAACCAAGAGATGATTCAAATTGATACTAAGAAT
ATTCTCTTTATCGTTGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCAATTGATGATGACTCATCATACATGCAAGAAATTGTGGCTGAAGATATTCAAAAATTCGGTC
TTATCCCTGAGTTTATCGGACGTTTGCCAGTCCTTGCGGCCCTTGAACAGTTAACGGTTGACGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTACCAAACCCTCTTGTCTTATGATGGGGTTGAACTGGAGTTTGACCAGGA
TGCTCTTGAAGCTATTGCAAGTAAGGCAATTGAACGTAAGACCGGTGCGCGTGGCCTTCGCTCTATCATTGAGGAAGTCA
TGATGGATGTCATGTTTGAGATTCCGAGTCAGGAAGATGTTACTAAGGTTCGTATTACAAAAGAAGCCGTTGACGGCACA
GCTGCTCCAGTTTTAGAAACAGCATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566