Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   V6T01_RS04760 Genome accession   NZ_CP145856
Coordinates   961940..963280 (+) Length   446 a.a.
NCBI ID   WP_410541045.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS1     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 956940..968280
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6T01_RS04730 (V6T01_04715) - 957010..957777 (-) 768 WP_151405000.1 amino acid ABC transporter ATP-binding protein -
  V6T01_RS04735 (V6T01_04720) - 957966..958616 (-) 651 WP_002886253.1 amino acid ABC transporter permease -
  V6T01_RS04740 (V6T01_04725) - 958628..959326 (-) 699 WP_002886251.1 amino acid ABC transporter permease -
  V6T01_RS04745 (V6T01_04730) - 959344..960177 (-) 834 WP_410541046.1 transporter substrate-binding domain-containing protein -
  V6T01_RS04750 (V6T01_04735) - 960187..960954 (-) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  V6T01_RS04755 (V6T01_04740) vicR 961240..961947 (+) 708 WP_002884978.1 response regulator YycF Regulator
  V6T01_RS04760 (V6T01_04745) vicK 961940..963280 (+) 1341 WP_410541045.1 cell wall metabolism sensor histidine kinase VicK Regulator
  V6T01_RS04765 (V6T01_04750) vicX 963286..964098 (+) 813 WP_371595677.1 MBL fold metallo-hydrolase Regulator
  V6T01_RS04770 (V6T01_04755) - 964157..964516 (+) 360 WP_371595678.1 YbaN family protein -
  V6T01_RS04775 (V6T01_04760) - 964568..965782 (-) 1215 WP_371595679.1 aminoacyltransferase -
  V6T01_RS04780 (V6T01_04765) yidA 965784..966593 (-) 810 WP_145516925.1 sugar-phosphatase -
  V6T01_RS04785 (V6T01_04770) - 966772..967629 (+) 858 WP_410541043.1 GNAT family N-acetyltransferase -
  V6T01_RS04790 (V6T01_04775) - 967722..968108 (+) 387 WP_049545096.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50935.17 Da        Isoelectric Point: 5.1606

>NTDB_id=940180 V6T01_RS04760 WP_410541045.1 961940..963280(+) (vicK) [Streptococcus salivarius strain KSS1]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDSELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDYETATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=940180 V6T01_RS04760 WP_410541045.1 961940..963280(+) (vicK) [Streptococcus salivarius strain KSS1]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTTTTTGTGGCTTTCTACTTTAT
TTTTCTTGCTTATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGAGTCAAGTCCCTAATGGCAGGTA
ACTATAATGAGGAGTTACGCTTAAAGGGTGATTCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGATGTC
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTCTCTTACATGAGTGATGGAGTTAT
TGCGACAAATCGCCGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTATGAAACAGCGA
CACAGATGTCCATTTTAGATTTATTAGATGGCGAAAATCCCTATACTTATAGTGAATTGCTCTCTAAGACTCCTGAAATT
CATTTGTCACGTCGAGATGCCAACGACGAGTTTGTGACCTTACGTGTTAATTTTGCCCTTATTCGTAAAGAATCAGGTTT
TATCTCAGGTCTGGTTGCCGTTCTTCACGATGCCACTGAGCAAGAAAAAGAAGAGCGTGAACGTCGACTCTTCGTCTCAA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCCTATCTGGAGGCACTTGATGATGGTGCTCTCGACGAA
GAGATTGCTCCTAACTTTATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
ATCACGTATTGACAATAAGAGTACCCAACTTGACGTTGAGATGACCAATTTCACGGCCTTCATGACCTATATCTTGAATC
GTTTTGATCAGATTAAAAGTCAAGAAACCAATACAGGTAAAACTTACGAAATCATTCGCGATTATCCGGTAAACTCAATT
TGGGTGGAGATTGATACAGATAAGATGACCCAGGTCGTGGATAATATTCTTAATAATGCTATCAAGTATTCGCCTGATGG
CGGTAAGATTACAGTGTCTATGAAGACAACTGATTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAAGATTTGCCTTTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCCCAGGGTGGAACTGGTCTA
GGCTTGTCCATTGCAAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCTAAAAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

HAMP domain (HAMP)

(38-79)

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.913

92.825

0.686
  micB Streptococcus pneumoniae Cp1015

67.898

97.085

0.659