Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   V6T01_RS02980 Genome accession   NZ_CP145856
Coordinates   591022..592248 (+) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain KSS1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 586022..597248
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6T01_RS02955 (V6T01_02940) - 586445..587716 (-) 1272 WP_110980889.1 hydroxymethylglutaryl-CoA reductase, degradative -
  V6T01_RS02960 (V6T01_02945) - 587718..588884 (-) 1167 WP_201041598.1 hydroxymethylglutaryl-CoA synthase -
  V6T01_RS02965 (V6T01_02950) - 589357..590217 (+) 861 WP_201041597.1 thymidylate synthase -
  V6T01_RS02970 (V6T01_02955) - 590326..590829 (+) 504 WP_347092976.1 dihydrofolate reductase -
  V6T01_RS02975 (V6T01_02960) - 590834..591004 (+) 171 WP_002886174.1 hypothetical protein -
  V6T01_RS02980 (V6T01_02965) clpX 591022..592248 (+) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  V6T01_RS02985 (V6T01_02970) yihA 592258..592857 (+) 600 WP_002885996.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  V6T01_RS02990 (V6T01_02975) - 592985..594361 (+) 1377 Protein_542 amino acid permease -
  V6T01_RS02995 (V6T01_02980) mmuM 594373..595323 (+) 951 WP_201059374.1 homocysteine S-methyltransferase -
  V6T01_RS03000 (V6T01_02985) - 595436..595690 (+) 255 WP_002886199.1 DUF1912 family protein -
  V6T01_RS03005 (V6T01_02990) - 595765..596133 (+) 369 WP_201042695.1 helix-hairpin-helix domain-containing protein -
  V6T01_RS03010 (V6T01_02995) plsY 596250..596891 (-) 642 WP_073689886.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=940173 V6T01_RS02980 WP_002890340.1 591022..592248(+) (clpX) [Streptococcus salivarius strain KSS1]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=940173 V6T01_RS02980 WP_002890340.1 591022..592248(+) (clpX) [Streptococcus salivarius strain KSS1]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATCGC
TGGGAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCTGAAACTCCGAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAGGACCGTGCC
AAACGTGCCTTGGCGGTAGCTGTTTACAATCACTATAAACGTATCAATTTCACAGAAAGTCGTGAAGACAATGATGTGGA
TTTGCAAAAATCAAATATTCTCATGATTGGACCAACTGGTTCAGGGAAGACTTTCTTGGCTCAGACCTTGGCTCGTAGCT
TGAATGTTCCATTTGCGATTGCGGATGCAACATCATTGACAGAGGCAGGTTATGTGGGTGAGGACGTGGAAAATATCCTC
CTCAAACTGATCCAAGCGGCAGACTTCAATATCGAACGTGCGGAACGTGGTATCATTTATGTTGACGAGATTGATAAGAT
TGCTAAAAAGGGTGAAAATGTATCAATCACTCGTGACGTTTCTGGTGAGGGGGTTCAACAAGCTCTCTTGAAGATTATCG
AAGGAACAGTAGCTAGCGTTCCCCCTCAAGGTGGTCGTAAACACCCTAACCAAGAGATGATTCAAATTGATACTAAGAAT
ATTCTCTTTATCGTTGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCAATTGATGATGACTCATCATACATGCAAGAAATTGTGGCTGAAGATATTCAAAAATTCGGTC
TTATCCCTGAGTTTATCGGACGTTTGCCAGTCCTTGCGGCCCTTGAACAGTTAACGGTTGACGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTACCAAACCCTCTTGTCTTATGATGGGGTTGAACTGGAGTTTGACCAGGA
TGCTCTTGAAGCTATTGCAAGTAAGGCAATTGAACGTAAGACCGGTGCGCGTGGCCTTCGCTCTATCATTGAGGAAGTCA
TGATGGATGTCATGTTTGAGATTCCGAGTCAGGAAGATGTTACTAAGGTTCGTATTACAAAAGAAGCCGTTGACGGCACA
GCTGCTCCAGTTTTAGAAACAGCATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566