Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACE168_RS09900 Genome accession   NZ_CP169634
Coordinates   1981113..1981769 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli str. K-12 substr. MG1655 strain K-12     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1976113..1986769
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE168_RS09870 (ACE168_09870) yecA 1977364..1978029 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  ACE168_RS09890 (ACE168_09890) pgsA 1978679..1979227 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACE168_RS09895 (ACE168_09895) uvrC 1979284..1981116 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACE168_RS09900 (ACE168_09900) letA 1981113..1981769 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACE168_RS09905 (ACE168_09905) - 1981911..1981982 (+) 72 Protein_1940 transcriptional regulator -
  ACE168_RS09910 (ACE168_09910) yecU 1982065..1982241 (+) 177 WP_000590347.1 protein YecU -
  ACE168_RS09915 (ACE168_09915) yecF 1982228..1982452 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACE168_RS09920 (ACE168_09920) sdiA 1982520..1983242 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  ACE168_RS09925 (ACE168_09925) tcyN 1983472..1984224 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACE168_RS09930 (ACE168_09930) tcyL 1984221..1984889 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  ACE168_RS09935 (ACE168_09935) dcyD 1984904..1985890 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=939905 ACE168_RS09900 WP_000611335.1 1981113..1981769(-) (letA) [Escherichia coli str. K-12 substr. MG1655 strain K-12]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=939905 ACE168_RS09900 WP_000611335.1 1981113..1981769(-) (letA) [Escherichia coli str. K-12 substr. MG1655 strain K-12]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486