Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACE1E5_RS15365 Genome accession   NZ_CP169544
Coordinates   3080765..3081421 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli O157:H7 strain AC-3     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3075765..3086421
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE1E5_RS15335 (ACE1E5_15335) yecA 3077017..3077682 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  ACE1E5_RS15355 (ACE1E5_15355) pgsA 3078331..3078879 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACE1E5_RS15360 (ACE1E5_15360) uvrC 3078936..3080768 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACE1E5_RS15365 (ACE1E5_15365) letA 3080765..3081421 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACE1E5_RS15370 (ACE1E5_15370) - 3081563..3081679 (+) 117 WP_001302039.1 hypothetical protein -
  ACE1E5_RS15375 (ACE1E5_15375) yecU 3081717..3081893 (+) 177 WP_001302050.1 protein YecU -
  ACE1E5_RS15380 (ACE1E5_15380) yecF 3081880..3082104 (+) 225 WP_000106479.1 DUF2594 family protein YecF -
  ACE1E5_RS15385 (ACE1E5_15385) sdiA 3082172..3082894 (-) 723 WP_001154288.1 transcriptional regulator SdiA -
  ACE1E5_RS15390 (ACE1E5_15390) tcyN 3083124..3083876 (-) 753 WP_001273005.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACE1E5_RS15395 (ACE1E5_15395) tcyL 3083873..3084541 (-) 669 WP_001158226.1 cystine ABC transporter permease -
  ACE1E5_RS15400 (ACE1E5_15400) dcyD 3084556..3085542 (-) 987 WP_001128225.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=939265 ACE1E5_RS15365 WP_000611328.1 3080765..3081421(-) (letA) [Escherichia coli O157:H7 strain AC-3]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=939265 ACE1E5_RS15365 WP_000611328.1 3080765..3081421(-) (letA) [Escherichia coli O157:H7 strain AC-3]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482