Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   LBA42_RS10390 Genome accession   NZ_CP145437
Coordinates   2022328..2023560 (+) Length   410 a.a.
NCBI ID   WP_024478652.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain HAC 39-1996     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2017328..2028560
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LBA42_RS10360 (LBA42_10360) - 2017392..2018069 (+) 678 WP_000221614.1 DnaD domain-containing protein -
  LBA42_RS10365 (LBA42_10365) tpiA 2018167..2018925 (+) 759 WP_000087897.1 triose-phosphate isomerase -
  LBA42_RS10370 (LBA42_10370) lytC 2018963..2020468 (+) 1506 WP_078139284.1 choline binding-anchored murein hydrolase LytC -
  LBA42_RS10375 (LBA42_10375) - 2020967..2021485 (+) 519 WP_000229860.1 Dps family protein -
  LBA42_RS10380 (LBA42_10380) - 2021615..2022121 (+) 507 WP_000162467.1 dihydrofolate reductase -
  LBA42_RS10385 (LBA42_10385) - 2022121..2022291 (+) 171 WP_000442260.1 hypothetical protein -
  LBA42_RS10390 (LBA42_10390) clpX 2022328..2023560 (+) 1233 WP_024478652.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  LBA42_RS10395 (LBA42_10395) yihA 2023569..2024156 (+) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  LBA42_RS10400 (LBA42_10400) - 2024167..2024547 (+) 381 WP_001140412.1 RidA family protein -
  LBA42_RS10405 (LBA42_10405) rapZ 2024599..2025489 (+) 891 WP_000163035.1 RNase adapter RapZ -
  LBA42_RS10410 (LBA42_10410) - 2025486..2026463 (+) 978 WP_001231086.1 YvcK family protein -
  LBA42_RS10415 (LBA42_10415) whiA 2026460..2027371 (+) 912 WP_000011306.1 DNA-binding protein WhiA -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45726.24 Da        Isoelectric Point: 4.4240

>NTDB_id=938747 LBA42_RS10390 WP_024478652.1 2022328..2023560(+) (clpX) [Streptococcus pneumoniae strain HAC 39-1996]
MPTTRNNDMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=938747 LBA42_RS10390 WP_024478652.1 2022328..2023560(+) (clpX) [Streptococcus pneumoniae strain HAC 39-1996]
ATGCCTACAACTAGGAATAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAGCCAAGAAGAAGTACAAAAAATAAT
CGCTGGGAACAACGCCTTTATCTGTAATGAATGTGTAGAGTTAGCCCAGGAAATCATTCGGGAAGAGTTGGCGGAAGAAG
TCTTGGCAGACTTGTCTGAGGTACCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATCGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCAGTTTACAATCACTACAAACGCATCAATTTCCACGATACGCGTGAAGAGTCGGAAGA
TGTAGATTTGCAGAAGTCAAACATCTTGATGATTGGCCCAACCGGTTCAGGGAAAACTTTCCTTGCTCAGACCTTGGCTA
AGAGCTTAAATGTGCCTTTTGCGATTGCGGATGCGACAGCTCTTACCGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATACTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTAATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterProScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.341

100

0.863
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561