Detailed information NTG0938739

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: LBA42_RS08985
• Genome accession: NZ_CP145437
• Coordinates: 1752582..1753649 (+)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain HAC 39-1996
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1747582..1758649

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LBA42_RS08970 (LBA42_08970)	amiA3	1748105..1750084 (+)	1980	WP_000742236.1	peptide ABC transporter substrate-binding protein	Regulator
LBA42_RS08975 (LBA42_08975)	amiC	1750151..1751647 (+)	1497	WP_000759905.1	ABC transporter permease	Regulator
LBA42_RS08980 (LBA42_08980)	amiD	1751647..1752573 (+)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
LBA42_RS08985 (LBA42_08985)	amiE	1752582..1753649 (+)	1068	WP_000159554.1	oligopeptide/dipeptide ABC transporter ATP-binding protein	Regulator
LBA42_RS08990 (LBA42_08990)	amiF	1753660..1754586 (+)	927	WP_001291294.1	ATP-binding cassette domain-containing protein	Regulator
LBA42_RS08995 (LBA42_08995)	-	1755077..1756014 (+)	938	Protein_1727	ABC transporter substrate-binding protein	-
LBA42_RS09000 (LBA42_09000)	-	1756026..1756903 (+)	878	Protein_1728	ABC transporter permease	-
LBA42_RS09005 (LBA42_09005)	-	1756916..1757719 (+)	804	WP_000157672.1	ATP-binding cassette domain-containing protein	-
LBA42_RS09010 (LBA42_09010)	treR	1757752..1758462 (-)	711	WP_000760673.1	trehalose operon repressor	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=938739 LBA42_RS08985 WP_000159554.1 1752582..1753649(+) (amiE) [Streptococcus pneumoniae strain HAC 39-1996]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=938739 LBA42_RS08985 WP_000159554.1 1752582..1753649(+) (amiE) [Streptococcus pneumoniae strain HAC 39-1996]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541