Detailed information NTG0938727

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LBA42_RS08530
• Genome accession: NZ_CP145437
• Coordinates: 1672594..1673631 (+)
• Length: 345 a.a.
• NCBI ID: WP_001813016.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain HAC 39-1996
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1667594..1678631

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LBA42_RS08495 (LBA42_08495)	yidC	1667629..1668555 (-)	927	WP_000835955.1	membrane protein insertase YidC	-
LBA42_RS08500 (LBA42_08500)	-	1668633..1668911 (-)	279	WP_001174614.1	acylphosphatase	-
LBA42_RS08505 (LBA42_08505)	-	1668945..1669685 (+)	741	WP_000152679.1	RNA methyltransferase	-
LBA42_RS08510 (LBA42_08510)	-	1669741..1670424 (+)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
LBA42_RS08515 (LBA42_08515)	asnA	1670536..1671528 (+)	993	WP_000747993.1	aspartate--ammonia ligase	-
LBA42_RS08520 (LBA42_08520)	rsmD	1671593..1672132 (+)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LBA42_RS08525 (LBA42_08525)	coaD	1672122..1672610 (+)	489	WP_001280746.1	pantetheine-phosphate adenylyltransferase	-
LBA42_RS08530 (LBA42_08530)	sepM	1672594..1673631 (+)	1038	WP_001813016.1	SepM family pheromone-processing serine protease	Regulator
LBA42_RS08535 (LBA42_08535)	-	1673689..1673919 (+)	231	WP_000250390.1	DUF1146 family protein	-
LBA42_RS08540 (LBA42_08540)	murA	1673943..1675226 (+)	1284	WP_000358032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
LBA42_RS08545 (LBA42_08545)	-	1675219..1675407 (+)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
LBA42_RS08550 (LBA42_08550)	endA	1675446..1676270 (+)	825	WP_001036791.1	DNA-entry nuclease EndA	Machinery gene
LBA42_RS08555 (LBA42_08555)	-	1676561..1677892 (+)	1332	WP_000390042.1	hemolysin family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37609.64 Da
• Isoelectric Point: 4.9590

>NTDB_id=938727 LBA42_RS08530 WP_001813016.1 1672594..1673631(+) (sepM) [Streptococcus pneumoniae strain HAC 39-1996]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKEIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIDLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=938727 LBA42_RS08530 WP_001813016.1 1672594..1673631(+) (sepM) [Streptococcus pneumoniae strain HAC 39-1996]
ATGAAAAAAAAGATTAGATGGCCTTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGAAATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGACTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588