Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   LBA42_RS08550 Genome accession   NZ_CP145437
Coordinates   1675446..1676270 (+) Length   274 a.a.
NCBI ID   WP_001036791.1    Uniprot ID   A0A0B7L7Z9
Organism   Streptococcus pneumoniae strain HAC 39-1996     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1670446..1681270
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LBA42_RS08515 (LBA42_08515) asnA 1670536..1671528 (+) 993 WP_000747993.1 aspartate--ammonia ligase -
  LBA42_RS08520 (LBA42_08520) rsmD 1671593..1672132 (+) 540 WP_000706963.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  LBA42_RS08525 (LBA42_08525) coaD 1672122..1672610 (+) 489 WP_001280746.1 pantetheine-phosphate adenylyltransferase -
  LBA42_RS08530 (LBA42_08530) sepM 1672594..1673631 (+) 1038 WP_001813016.1 SepM family pheromone-processing serine protease Regulator
  LBA42_RS08535 (LBA42_08535) - 1673689..1673919 (+) 231 WP_000250390.1 DUF1146 family protein -
  LBA42_RS08540 (LBA42_08540) murA 1673943..1675226 (+) 1284 WP_000358032.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  LBA42_RS08545 (LBA42_08545) - 1675219..1675407 (+) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  LBA42_RS08550 (LBA42_08550) endA 1675446..1676270 (+) 825 WP_001036791.1 DNA-entry nuclease EndA Machinery gene
  LBA42_RS08555 (LBA42_08555) - 1676561..1677892 (+) 1332 WP_000390042.1 hemolysin family protein -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29939.65 Da        Isoelectric Point: 10.1700

>NTDB_id=938728 LBA42_RS08550 WP_001036791.1 1675446..1676270(+) (endA) [Streptococcus pneumoniae strain HAC 39-1996]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=938728 LBA42_RS08550 WP_001036791.1 1675446..1676270(+) (endA) [Streptococcus pneumoniae strain HAC 39-1996]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACCAAGCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7L7Z9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.54

100

0.985
  endA Streptococcus pneumoniae D39

98.54

100

0.985
  endA Streptococcus pneumoniae R6

98.54

100

0.985
  endA Streptococcus pneumoniae TIGR4

98.54

100

0.985