Detailed information NTG0938726

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: LBA42_RS08370
• Genome accession: NZ_CP145437
• Coordinates: 1644805..1645815 (+)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain HAC 39-1996
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1639805..1650815

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LBA42_RS08340 (LBA42_08340)	-	1640676..1640882 (+)	207	Protein_1619	hypothetical protein	-
LBA42_RS08345 (LBA42_08345)	-	1640879..1641073 (+)	195	WP_000715302.1	hypothetical protein	-
LBA42_RS08350 (LBA42_08350)	-	1641060..1641944 (+)	885	WP_000219359.1	ABC transporter ATP-binding protein	-
LBA42_RS08355 (LBA42_08355)	-	1641946..1642683 (+)	738	WP_000832916.1	ABC transporter permease	-
LBA42_RS08360 (LBA42_08360)	-	1642683..1643780 (+)	1098	WP_000893503.1	sensor histidine kinase	-
LBA42_RS08365 (LBA42_08365)	-	1643781..1644380 (+)	600	WP_000866703.1	response regulator transcription factor	-
LBA42_RS08370 (LBA42_08370)	ccpA	1644805..1645815 (+)	1011	WP_000990607.1	catabolite control protein A	Regulator
LBA42_RS08375 (LBA42_08375)	-	1645879..1646262 (+)	384	WP_001092022.1	hypothetical protein	-
LBA42_RS08380 (LBA42_08380)	-	1646291..1647253 (-)	963	WP_001124786.1	asparaginase	-
LBA42_RS08385 (LBA42_08385)	-	1647319..1648707 (+)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
LBA42_RS08390 (LBA42_08390)	-	1648742..1649194 (-)	453	WP_000079148.1	universal stress protein	-
LBA42_RS08395 (LBA42_08395)	-	1649356..1649650 (+)	295	Protein_1630	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=938726 LBA42_RS08370 WP_000990607.1 1644805..1645815(+) (ccpA) [Streptococcus pneumoniae strain HAC 39-1996]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=938726 LBA42_RS08370 WP_000990607.1 1644805..1645815(+) (ccpA) [Streptococcus pneumoniae strain HAC 39-1996]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568