Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   LBA42_RS05135 Genome accession   NZ_CP145437
Coordinates   1028169..1028858 (-) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain HAC 39-1996     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1023169..1033858
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LBA42_RS05110 (LBA42_05110) - 1023843..1024172 (-) 330 WP_000619581.1 transposase -
  LBA42_RS05115 (LBA42_05115) - 1024835..1025193 (+) 359 Protein_1015 lanthionine synthetase LanC family protein -
  LBA42_RS05120 (LBA42_05120) - 1025093..1025563 (+) 471 WP_001809487.1 lanthionine synthetase LanC family protein -
  LBA42_RS05125 (LBA42_05125) - 1025722..1026954 (+) 1233 WP_000765684.1 MFS transporter -
  LBA42_RS05130 (LBA42_05130) cbpJ 1027072..1028070 (-) 999 WP_000771053.1 choline-binding protein CbpJ -
  LBA42_RS05135 (LBA42_05135) covR 1028169..1028858 (-) 690 WP_000518008.1 response regulator transcription factor Regulator
  LBA42_RS05140 (LBA42_05140) gndA 1028870..1030294 (-) 1425 WP_000158793.1 NADP-dependent phosphogluconate dehydrogenase -
  LBA42_RS05145 (LBA42_05145) mapZ 1030370..1031764 (-) 1395 WP_000039255.1 mid-cell-anchored protein MapZ -
  LBA42_RS05150 (LBA42_05150) - 1031777..1032934 (-) 1158 WP_000711414.1 class I SAM-dependent RNA methyltransferase -
  LBA42_RS05160 (LBA42_05160) gpsB 1033420..1033761 (-) 342 WP_000200645.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=938694 LBA42_RS05135 WP_000518008.1 1028169..1028858(-) (covR) [Streptococcus pneumoniae strain HAC 39-1996]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=938694 LBA42_RS05135 WP_000518008.1 1028169..1028858(-) (covR) [Streptococcus pneumoniae strain HAC 39-1996]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCAATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467