Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   LBA42_RS04450 Genome accession   NZ_CP145437
Coordinates   883121..884764 (+) Length   547 a.a.
NCBI ID   WP_078133841.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain HAC 39-1996     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 878121..889764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LBA42_RS04400 (LBA42_04400) blpN 878484..878687 (-) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  LBA42_RS04405 (LBA42_04405) blpM 878703..878957 (-) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  LBA42_RS04410 (LBA42_04410) - 879107..879911 (-) 805 Protein_874 IS5 family transposase -
  LBA42_RS04415 (LBA42_04415) - 880109..880513 (-) 405 WP_000846944.1 hypothetical protein -
  LBA42_RS04420 (LBA42_04420) - 880510..880674 (-) 165 WP_000727118.1 hypothetical protein -
  LBA42_RS04425 (LBA42_04425) - 880971..881090 (-) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  LBA42_RS04430 (LBA42_04430) blpU 881093..881323 (-) 231 WP_000379964.1 bacteriocin-like peptide BlpU -
  LBA42_RS04435 (LBA42_04435) blpJ 881392..881661 (-) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  LBA42_RS04440 (LBA42_04440) blpI 882128..882325 (-) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  LBA42_RS04445 (LBA42_04445) comA/nlmT 882607..883194 (+) 588 WP_001810228.1 cysteine peptidase family C39 domain-containing protein Regulator
  LBA42_RS04450 (LBA42_04450) comA/nlmT 883121..884764 (+) 1644 WP_078133841.1 peptide cleavage/export ABC transporter Regulator
  LBA42_RS04455 (LBA42_04455) - 884775..886136 (+) 1362 WP_001069091.1 bacteriocin secretion accessory protein -
  LBA42_RS04460 (LBA42_04460) blpC 886193..886348 (+) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  LBA42_RS04465 (LBA42_04465) - 886390..887730 (-) 1341 WP_001017638.1 sensor histidine kinase -
  LBA42_RS04470 (LBA42_04470) comE/blpR 887744..888481 (-) 738 WP_001219120.1 LytTR family DNA-binding domain-containing protein Regulator
  LBA42_RS04475 (LBA42_04475) - 888486..888824 (-) 339 WP_000682135.1 LytTR family DNA-binding domain-containing protein -
  LBA42_RS04480 (LBA42_04480) - 889101..889430 (+) 330 WP_000132572.1 hypothetical protein -

Sequence

Protein


Download         Length: 547 a.a.        Molecular weight: 61617.57 Da        Isoelectric Point: 6.5088

>NTDB_id=938690 LBA42_RS04450 WP_078133841.1 883121..884764(+) (comA/nlmT) [Streptococcus pneumoniae strain HAC 39-1996]
MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIF
ELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKLVLNILILWFG
AQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLS
YKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIF
NGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSPVLILDEATSG
LDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1644 bp        

>NTDB_id=938690 LBA42_RS04450 WP_078133841.1 883121..884764(+) (comA/nlmT) [Streptococcus pneumoniae strain HAC 39-1996]
ATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTAGATGAATACAT
CCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCT
TCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGATGTGATTTTATCCTATATTCGCCATATTTTT
GAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGGTTCACAGATGCTAACTCTATTATAGA
TGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGGGGAGTCTTGCTGGCACAAA
ACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACCTTTCGAA
AAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTGAAACTAT
AAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCCTTTAAGC
TCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATGGTTTGGC
GCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTTTTTCTTACTTTACAACTCC
TATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTCTATCTAG
TCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTGATGGGCGATATTGAATTTGATGACCTTTCT
TATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGG
AGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGGCATATTTCCATCA
ATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCCCAACAAGCCTATATCTTT
AATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGATTAGTCAAGAAGATATTCTAAAAGCTTGTGAAGT
AGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAG
GACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCTCCTGTTTTAATACTAGATGAAGCTACTAGCGGT
CTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAACTGATAAAACCATTCTCTTTGTAGCCCATCG
TCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGCCACCAAGAGT
TAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(2-268)

ABC transporter (ABC_tran)

(330-479)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.894

99.817

0.728
  comA Streptococcus mitis NCTC 12261

67.459

100

0.675
  comA Streptococcus pneumoniae D39

67.093

100

0.671
  comA Streptococcus pneumoniae R6

67.093

100

0.671
  comA Streptococcus pneumoniae Rx1

67.093

100

0.671
  comA Streptococcus gordonii str. Challis substr. CH1

66.788

100

0.669
  comA Streptococcus mitis SK321

66.91

100

0.669
  comA Streptococcus pneumoniae TIGR4

66.728

100

0.667