Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   LBA42_RS04445 Genome accession   NZ_CP145437
Coordinates   882607..883194 (+) Length   195 a.a.
NCBI ID   WP_001810228.1    Uniprot ID   A0A380LSF4
Organism   Streptococcus pneumoniae strain HAC 39-1996     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 877607..888194
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LBA42_RS04390 (LBA42_04390) - 877868..877987 (-) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  LBA42_RS04395 (LBA42_04395) cipB 878091..878240 (-) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  LBA42_RS04400 (LBA42_04400) blpN 878484..878687 (-) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  LBA42_RS04405 (LBA42_04405) blpM 878703..878957 (-) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  LBA42_RS04410 (LBA42_04410) - 879107..879911 (-) 805 Protein_874 IS5 family transposase -
  LBA42_RS04415 (LBA42_04415) - 880109..880513 (-) 405 WP_000846944.1 hypothetical protein -
  LBA42_RS04420 (LBA42_04420) - 880510..880674 (-) 165 WP_000727118.1 hypothetical protein -
  LBA42_RS04425 (LBA42_04425) - 880971..881090 (-) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  LBA42_RS04430 (LBA42_04430) blpU 881093..881323 (-) 231 WP_000379964.1 bacteriocin-like peptide BlpU -
  LBA42_RS04435 (LBA42_04435) blpJ 881392..881661 (-) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  LBA42_RS04440 (LBA42_04440) blpI 882128..882325 (-) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  LBA42_RS04445 (LBA42_04445) comA/nlmT 882607..883194 (+) 588 WP_001810228.1 cysteine peptidase family C39 domain-containing protein Regulator
  LBA42_RS04450 (LBA42_04450) comA/nlmT 883121..884764 (+) 1644 WP_078133841.1 peptide cleavage/export ABC transporter Regulator
  LBA42_RS04455 (LBA42_04455) - 884775..886136 (+) 1362 WP_001069091.1 bacteriocin secretion accessory protein -
  LBA42_RS04460 (LBA42_04460) blpC 886193..886348 (+) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  LBA42_RS04465 (LBA42_04465) - 886390..887730 (-) 1341 WP_001017638.1 sensor histidine kinase -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22369.84 Da        Isoelectric Point: 9.7306

>NTDB_id=938689 LBA42_RS04445 WP_001810228.1 882607..883194(+) (comA/nlmT) [Streptococcus pneumoniae strain HAC 39-1996]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLR

Nucleotide


Download         Length: 588 bp        

>NTDB_id=938689 LBA42_RS04445 WP_001810228.1 882607..883194(+) (comA/nlmT) [Streptococcus pneumoniae strain HAC 39-1996]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTAGATGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380LSF4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

59.89

93.333

0.559
  comA Streptococcus mitis NCTC 12261

54.891

94.359

0.518
  comA Streptococcus mitis SK321

54.348

94.359

0.513
  comA Streptococcus pneumoniae TIGR4

53.804

94.359

0.508
  comA Streptococcus pneumoniae Rx1

53.804

94.359

0.508
  comA Streptococcus pneumoniae D39

53.804

94.359

0.508
  comA Streptococcus pneumoniae R6

53.804

94.359

0.508
  comA Streptococcus gordonii str. Challis substr. CH1

52.717

94.359

0.497