Detailed information    

insolico Bioinformatically predicted

Overview


Name   comK/comK1   Type   Regulator
Locus tag   V6D01_RS09095 Genome accession   NZ_CP145244
Coordinates   1858870..1859445 (-) Length   191 a.a.
NCBI ID   WP_023350568.1    Uniprot ID   -
Organism   Staphylococcus capitis subsp. urealyticus strain Sc1365670     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1813647..1858358 1858870..1859445 flank 512


Gene organization within MGE regions


Location: 1813647..1859445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6D01_RS08725 (V6D01_08705) - 1813647..1813844 (-) 198 WP_023350503.1 hypothetical protein -
  V6D01_RS08730 (V6D01_08710) - 1814824..1816287 (-) 1464 WP_367122772.1 SH3 domain-containing protein -
  V6D01_RS08735 (V6D01_08715) - 1816262..1816672 (-) 411 WP_023350506.1 phage holin -
  V6D01_RS08740 (V6D01_08720) - 1816717..1817250 (-) 534 WP_367122774.1 hypothetical protein -
  V6D01_RS08745 (V6D01_08725) - 1817250..1817765 (-) 516 WP_206414095.1 hypothetical protein -
  V6D01_RS08750 (V6D01_08730) - 1817806..1817952 (-) 147 WP_102695953.1 XkdX family protein -
  V6D01_RS08755 (V6D01_08735) - 1817945..1818274 (-) 330 WP_367122775.1 hypothetical protein -
  V6D01_RS08760 (V6D01_08740) - 1818286..1819281 (-) 996 WP_367122776.1 BppU family phage baseplate upper protein -
  V6D01_RS08765 (V6D01_08745) - 1819334..1820536 (-) 1203 WP_367122777.1 N-acetylglucosaminidase -
  V6D01_RS08770 (V6D01_08750) - 1821185..1821421 (-) 237 Protein_1670 CHAP domain-containing protein -
  V6D01_RS08775 (V6D01_08755) - 1821736..1821867 (-) 132 WP_255263171.1 hypothetical protein -
  V6D01_RS08780 (V6D01_08760) - 1821921..1822319 (-) 399 WP_367122779.1 hypothetical protein -
  V6D01_RS08785 (V6D01_08765) - 1822300..1822722 (-) 423 WP_002470002.1 hypothetical protein -
  V6D01_RS08790 (V6D01_08770) - 1822736..1823923 (-) 1188 WP_367122780.1 BppU family phage baseplate upper protein -
  V6D01_RS08795 (V6D01_08775) - 1823936..1825822 (-) 1887 WP_367122781.1 M14 family metallopeptidase -
  V6D01_RS08800 (V6D01_08780) - 1825825..1827285 (-) 1461 WP_367122782.1 phage tail protein -
  V6D01_RS08805 (V6D01_08785) - 1827297..1828253 (-) 957 WP_367122783.1 phage tail domain-containing protein -
  V6D01_RS08810 (V6D01_08790) - 1828265..1832173 (-) 3909 WP_367122784.1 phage tail protein -
  V6D01_RS08815 (V6D01_08795) - 1832188..1832532 (-) 345 WP_367122785.1 hypothetical protein -
  V6D01_RS08820 (V6D01_08800) - 1832574..1832933 (-) 360 WP_367122786.1 tail assembly chaperone -
  V6D01_RS08825 (V6D01_08805) - 1832994..1833548 (-) 555 WP_002436441.1 phage major tail protein, TP901-1 family -
  V6D01_RS08830 (V6D01_08810) - 1833595..1833984 (-) 390 WP_367122787.1 hypothetical protein -
  V6D01_RS08835 (V6D01_08815) - 1833995..1834354 (-) 360 WP_367122788.1 HK97-gp10 family putative phage morphogenesis protein -
  V6D01_RS08840 (V6D01_08820) - 1834354..1834656 (-) 303 WP_367122789.1 hypothetical protein -
  V6D01_RS08845 (V6D01_08825) - 1834653..1834982 (-) 330 WP_002436519.1 phage head-tail connector protein -
  V6D01_RS08850 (V6D01_08830) - 1834984..1835253 (-) 270 WP_367122790.1 hypothetical protein -
  V6D01_RS08855 (V6D01_08835) - 1835276..1836190 (-) 915 WP_367122791.1 phage major capsid protein -
  V6D01_RS08860 (V6D01_08840) - 1836208..1836813 (-) 606 WP_367122792.1 DUF4355 domain-containing protein -
  V6D01_RS08865 (V6D01_08845) - 1837067..1837210 (-) 144 WP_169922991.1 hypothetical protein -
  V6D01_RS08870 (V6D01_08850) - 1837203..1837748 (-) 546 WP_367122793.1 hypothetical protein -
  V6D01_RS08875 (V6D01_08855) - 1837768..1838718 (-) 951 Protein_1691 minor capsid protein -
  V6D01_RS08880 (V6D01_08860) - 1838725..1840221 (-) 1497 WP_367122794.1 phage portal protein -
  V6D01_RS08885 (V6D01_08865) - 1840235..1841527 (-) 1293 WP_367122795.1 PBSX family phage terminase large subunit -
  V6D01_RS08890 (V6D01_08870) - 1841520..1841864 (-) 345 WP_268218651.1 phBC6A51 family helix-turn-helix protein -
  V6D01_RS08895 (V6D01_08875) - 1842140..1842556 (-) 417 WP_367122796.1 transcriptional regulator -
  V6D01_RS08900 (V6D01_08880) - 1842627..1842794 (-) 168 WP_367122797.1 regulator -
  V6D01_RS08905 (V6D01_08885) dut 1842843..1843265 (-) 423 WP_367122798.1 dUTP diphosphatase -
  V6D01_RS08910 (V6D01_08890) - 1843266..1843457 (-) 192 WP_367122799.1 hypothetical protein -
  V6D01_RS08915 (V6D01_08895) - 1843444..1843593 (-) 150 WP_367122800.1 hypothetical protein -
  V6D01_RS08920 (V6D01_08900) - 1843642..1843845 (-) 204 WP_367122801.1 hypothetical protein -
  V6D01_RS08925 (V6D01_08905) - 1843829..1844260 (-) 432 WP_367122802.1 hypothetical protein -
  V6D01_RS08930 (V6D01_08910) - 1844247..1844432 (-) 186 WP_367123000.1 hypothetical protein -
  V6D01_RS08935 (V6D01_08915) - 1844583..1844897 (-) 315 Protein_1703 nucleoside 2-deoxyribosyltransferase -
  V6D01_RS08940 (V6D01_08920) - 1844894..1845097 (-) 204 WP_367122803.1 hypothetical protein -
  V6D01_RS08945 (V6D01_08925) - 1845098..1845463 (-) 366 WP_367122804.1 SA1788 family PVL leukocidin-associated protein -
  V6D01_RS08950 (V6D01_08930) - 1845464..1845658 (-) 195 WP_367122805.1 hypothetical protein -
  V6D01_RS08955 (V6D01_08935) - 1845651..1846058 (-) 408 WP_367122806.1 DUF1064 domain-containing protein -
  V6D01_RS08960 (V6D01_08940) - 1846067..1846312 (-) 246 WP_367122807.1 hypothetical protein -
  V6D01_RS08965 (V6D01_08945) - 1846315..1846470 (-) 156 WP_049399495.1 hypothetical protein -
  V6D01_RS08970 (V6D01_08950) - 1846464..1847234 (-) 771 WP_367122808.1 ATP-binding protein -
  V6D01_RS08975 (V6D01_08955) - 1847245..1848015 (-) 771 WP_367123001.1 conserved phage C-terminal domain-containing protein -
  V6D01_RS08980 (V6D01_08960) - 1848002..1848682 (-) 681 WP_367122809.1 putative HNHc nuclease -
  V6D01_RS08985 (V6D01_08965) ssbA 1848698..1849126 (-) 429 WP_367122810.1 single-stranded DNA-binding protein Machinery gene
  V6D01_RS08990 (V6D01_08970) - 1849119..1849772 (-) 654 WP_367122811.1 ERF family protein -
  V6D01_RS08995 (V6D01_08975) - 1849765..1849986 (-) 222 WP_002469938.1 DUF2483 family protein -
  V6D01_RS09000 (V6D01_08980) - 1849952..1850234 (-) 283 Protein_1716 chordopoxvirus fusion protein -
  V6D01_RS09005 (V6D01_08985) - 1850256..1850474 (-) 219 WP_023350553.1 hypothetical protein -
  V6D01_RS09010 (V6D01_08990) - 1850486..1850698 (-) 213 WP_367122812.1 DUF771 domain-containing protein -
  V6D01_RS09015 (V6D01_08995) - 1850702..1850869 (-) 168 WP_023350555.1 hypothetical protein -
  V6D01_RS09020 (V6D01_09000) - 1850971..1851165 (-) 195 WP_023350556.1 hypothetical protein -
  V6D01_RS09025 (V6D01_09005) - 1851248..1851424 (+) 177 WP_023350557.1 hypothetical protein -
  V6D01_RS09030 (V6D01_09010) - 1851450..1851548 (-) 99 Protein_1722 hypothetical protein -
  V6D01_RS09035 (V6D01_09015) - 1851638..1851814 (-) 177 WP_023350559.1 hypothetical protein -
  V6D01_RS09040 (V6D01_09020) - 1851897..1852667 (-) 771 WP_023350560.1 DUF6551 family protein -
  V6D01_RS09045 (V6D01_09025) - 1852664..1853620 (-) 957 WP_049307539.1 ParB N-terminal domain-containing protein -
  V6D01_RS09050 (V6D01_09030) - 1853636..1853875 (-) 240 WP_367122814.1 helix-turn-helix domain-containing protein -
  V6D01_RS09055 (V6D01_09035) - 1854069..1854398 (+) 330 WP_002469947.1 helix-turn-helix transcriptional regulator -
  V6D01_RS09060 (V6D01_09040) - 1854410..1854874 (+) 465 WP_367122815.1 ImmA/IrrE family metallo-endopeptidase -
  V6D01_RS09065 (V6D01_09045) - 1854884..1855561 (+) 678 WP_367122816.1 hypothetical protein -
  V6D01_RS09070 (V6D01_09050) - 1855705..1855917 (+) 213 WP_367081037.1 hypothetical protein -
  V6D01_RS09075 (V6D01_09055) - 1856138..1857121 (+) 984 WP_367122817.1 DUF3644 domain-containing protein -
  V6D01_RS09080 (V6D01_09060) - 1857297..1858358 (+) 1062 WP_367122818.1 tyrosine-type recombinase/integrase -
  V6D01_RS09095 (V6D01_09075) comK/comK1 1858870..1859445 (-) 576 WP_023350568.1 competence protein ComK Regulator

Sequence


Protein


Download         Length: 191 a.a.        Molecular weight: 22722.82 Da        Isoelectric Point: 9.5768

>NTDB_id=938149 V6D01_RS09095 WP_023350568.1 1858870..1859445(-) (comK/comK1) [Staphylococcus capitis subsp. urealyticus strain Sc1365670]
MTNFSESIYVIRKGDMLIRPRYDEYQQTSGAEIIRFDKSRKESPFKVQRIIERSCKFYGNSYLSKKSETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQDENIWINMHYIDNIKELKNRKSKVIFANGESFILNVSYHSLWHQYTNAIIYYYMVDKHARM
KSNNPEQPIDYNQSSLNIFEALSRYSLLDDK

Nucleotide


Download         Length: 576 bp        

>NTDB_id=938149 V6D01_RS09095 WP_023350568.1 1858870..1859445(-) (comK/comK1) [Staphylococcus capitis subsp. urealyticus strain Sc1365670]
ATGACTAATTTTAGTGAATCAATCTATGTTATTAGAAAAGGTGACATGTTAATTCGACCAAGGTATGATGAATATCAGCA
AACTTCAGGTGCAGAAATTATAAGATTTGATAAATCACGAAAGGAAAGTCCATTTAAAGTTCAAAGAATTATCGAGAGGT
CCTGCAAATTCTATGGTAATAGCTACCTAAGCAAAAAATCTGAAACTAATAGAATTACAGGTATCTCTAGTAAACCACCT
ATTTTACTTACCCCTTTATTTCCAACTTATTTTTTCCCAACACATTCTGATCGACAAGACGAAAACATCTGGATAAACAT
GCATTATATCGACAACATCAAAGAACTTAAAAATCGTAAAAGTAAAGTGATATTTGCTAATGGTGAATCATTTATATTAA
ACGTTTCATATCATAGCTTATGGCATCAATATACAAATGCGATTATTTATTATTATATGGTAGATAAACATGCACGTATG
AAATCAAATAATCCAGAACAACCCATTGATTATAATCAATCATCGTTAAATATATTTGAAGCTCTCTCAAGGTATTCTCT
TTTAGATGATAAGTAG

Domains


Predicted by InterproScan.

(8-157)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

76.064

98.429

0.749

  comK/comK1 Staphylococcus aureus N315

76.064

98.429

0.749