Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACET1C_RS10395 Genome accession   NZ_CP168987
Coordinates   2101141..2101797 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain UTAK-10     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2096141..2106797
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACET1C_RS10360 (ACET1C_10360) dcyD 2097021..2098007 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  ACET1C_RS10365 (ACET1C_10365) tcyL 2098022..2098690 (+) 669 WP_001158206.1 cystine ABC transporter permease -
  ACET1C_RS10370 (ACET1C_10370) tcyN 2098687..2099439 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACET1C_RS10375 (ACET1C_10375) sdiA 2099669..2100391 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  ACET1C_RS10380 (ACET1C_10380) yecF 2100458..2100682 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACET1C_RS10385 (ACET1C_10385) yecU 2100669..2100845 (-) 177 WP_000590347.1 protein YecU -
  ACET1C_RS10390 (ACET1C_10390) - 2100928..2100999 (-) 72 Protein_2032 transcriptional regulator -
  ACET1C_RS10395 (ACET1C_10395) letA 2101141..2101797 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACET1C_RS10400 (ACET1C_10400) uvrC 2101794..2103626 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  ACET1C_RS10405 (ACET1C_10405) pgsA 2103683..2104231 (+) 549 WP_001160189.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACET1C_RS10425 (ACET1C_10425) yecA 2104881..2105547 (+) 667 Protein_2036 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=937517 ACET1C_RS10395 WP_000611335.1 2101141..2101797(+) (letA) [Escherichia coli strain UTAK-10]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=937517 ACET1C_RS10395 WP_000611335.1 2101141..2101797(+) (letA) [Escherichia coli strain UTAK-10]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486