Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   LLID5_RS08175 Genome accession   NZ_AP025701
Coordinates   1715864..1717339 (-) Length   491 a.a.
NCBI ID   WP_251918414.1    Uniprot ID   -
Organism   Lactococcus lactis strain ID-5     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1710864..1722339
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLID5_RS08155 (LLID5_16120) murG 1711001..1712074 (-) 1074 WP_251918410.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  LLID5_RS08160 (LLID5_16130) murD 1712284..1713636 (-) 1353 WP_153242219.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  LLID5_RS08165 (LLID5_16140) - 1713967..1714308 (-) 342 WP_010906046.1 P-II family nitrogen regulator -
  LLID5_RS08170 (LLID5_16150) - 1714440..1715681 (-) 1242 WP_251918412.1 ammonium transporter -
  LLID5_RS08175 (LLID5_16160) covS 1715864..1717339 (-) 1476 WP_251918414.1 HAMP domain-containing histidine kinase Regulator
  LLID5_RS08180 (LLID5_16170) covR 1717348..1718040 (-) 693 WP_003130756.1 response regulator transcription factor Regulator
  LLID5_RS08185 (LLID5_16180) - 1718196..1718726 (-) 531 WP_058212571.1 DUF177 domain-containing protein -
  LLID5_RS08190 (LLID5_16190) - 1718857..1719102 (-) 246 WP_003130760.1 type B 50S ribosomal protein L31 -
  LLID5_RS08195 (LLID5_16200) - 1719258..1719722 (-) 465 WP_251918416.1 hypothetical protein -
  LLID5_RS08200 (LLID5_16210) - 1719804..1720166 (-) 363 WP_251918418.1 TIGR02328 family protein -
  LLID5_RS12070 - 1720515..1720646 (-) 132 WP_286010145.1 hypothetical protein -
  LLID5_RS08205 (LLID5_16220) - 1720650..1721105 (-) 456 WP_251918420.1 CHAP domain-containing protein -
  LLID5_RS08210 (LLID5_16230) - 1721167..1722003 (-) 837 WP_023164354.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 491 a.a.        Molecular weight: 56118.98 Da        Isoelectric Point: 4.8253

>NTDB_id=93741 LLID5_RS08175 WP_251918414.1 1715864..1717339(-) (covS) [Lactococcus lactis strain ID-5]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSIIKEEQQLLTRSMDSVEEVLEKADAPL
NSSNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHTFGFQNQANNEMKEIRGENPGYLVQRKII
SKSTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIVAQLIGYFMANYFMKPLEKLYQGMQEMANDPTNDFEPIEI
QSGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVCNRALKNFQLLHDDFEIVLDNRLIYPTHARISENHFEQGLRILLDNAAKYSPD
DRKEIGITVSEDEQFVITSVSDKGIGISEEDINHLFERFFRADKARNREIGGTGLGLSILARLAENYQGEIEVNSELGLG
STFTLKFPKIK

Nucleotide


Download         Length: 1476 bp        

>NTDB_id=93741 LLID5_RS08175 WP_251918414.1 1715864..1717339(-) (covS) [Lactococcus lactis strain ID-5]
ATGAAAAAATTATTTACTTTCAATAAGAAAAAAGAGACGGTAGAGGAAAGTTCGGCTAAGCGGTCTATCATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTTTGTTTGCTACTTTGACTTATCAATTGACAATCAGTTCTA
TTATTAAAGAAGAACAACAATTATTAACTCGCTCTATGGATAGTGTTGAGGAAGTCTTAGAAAAAGCAGATGCTCCTTTG
AATTCATCGAATTTGAACACATATATTGAAGCGACATCAAAGATTCAAAATGGTGAGTCTGAAGGAATGAGTTTGGGTAG
TATCATTGGGACACGGAAAGCATTTTATATTTATGACTTAAATCATAAATTATTGTATTCAACGAATCGACATACTTTTG
GTTTTCAGAATCAGGCTAATAATGAAATGAAAGAGATTCGGGGAGAAAATCCAGGTTATTTAGTTCAGAGAAAAATTATT
TCTAAGTCAACAGGACAAGTTGTGGGATACTTACAGGCTTTTTATGATACGACGACTTATCATCGAATTTCTAATCTTCT
TTTGATTGTCTTGTTAATTTTAGAAATTGTTGCCTTGATTGTCGCTCAGTTGATTGGTTATTTCATGGCGAATTACTTTA
TGAAACCATTGGAAAAACTTTATCAGGGCATGCAAGAAATGGCAAATGATCCAACAAATGATTTTGAACCGATTGAAATT
CAAAGTGGAGATGAAATCGAAGAGTTGGCTCATGTTTACAATGATATGATGTTGAAGATGAAGGCATATCTTGAACAGCA
AAATCGCTTTGTTTCTGATGTTTCTCATGAATTAAGAACACCTTTAGCTGTCTTGGATGGACATATTAACTTGTTGAATC
GATGGGGGAAAAATGATCCAGAAGTATTAGATGAATCTTTGCAGGCAAGTTTAGATGAAGTTGATCGAATGAAGAAAATG
CTTGAGGAGATGTTGGCTCTTGCTCGCCTTGAAAATGTTGACTTATCAAGTGAAGAACTGGATTGTGATGTTGGAAAAGT
TTGTAATCGGGCCCTTAAGAATTTTCAGCTTTTGCATGATGATTTTGAAATAGTGCTTGATAACCGGCTTATTTATCCCA
CTCATGCGCGAATTTCGGAAAATCATTTTGAACAAGGTTTACGAATTCTGTTAGATAATGCTGCTAAATACTCTCCTGAT
GATCGTAAAGAAATCGGGATTACTGTTTCTGAGGATGAACAGTTTGTCATTACGAGTGTATCTGACAAAGGAATTGGAAT
TTCAGAAGAAGATATTAATCATCTTTTTGAGCGTTTCTTTAGAGCGGACAAGGCTCGCAATCGAGAAATTGGTGGAACTG
GTTTAGGTTTATCAATTTTAGCTCGATTGGCAGAAAATTATCAAGGGGAAATTGAGGTAAATTCAGAACTGGGTCTTGGT
TCAACTTTTACACTAAAATTCCCGAAAATAAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-489)

ArlS sensor domain (ArlS_N)

(53-185)

HAMP domain (HAMP)

(208-258)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

99.593

100

0.996

Multiple sequence alignment