Detailed information NTG0937052

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: V5G01_RS08580
• Genome accession: NZ_CP145083
• Coordinates: 1639991..1640851 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain WHO_D_2024
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1634991..1645851

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V5G01_RS08565 (V5G01_08595)	dapD	1635501..1636322 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
V5G01_RS08570 (V5G01_08600)	pgi	1636532..1638175 (-)	1644	WP_003689806.1	glucose-6-phosphate isomerase	-
V5G01_RS08575 (V5G01_08605)	pilG	1638685..1639917 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
V5G01_RS08580 (V5G01_08610)	pilD	1639991..1640851 (+)	861	WP_003689814.1	A24 family peptidase	Machinery gene
V5G01_RS08585 (V5G01_08615)	coaE	1640848..1641480 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
V5G01_RS08590 (V5G01_08620)	-	1641473..1641682 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
V5G01_RS08595 (V5G01_08625)	pilF	1641768..1643444 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
V5G01_RS08605 (V5G01_08635)	-	1643782..1644228 (-)	447	WP_003689818.1	DUF441 domain-containing protein	-
V5G01_RS08610 (V5G01_08640)	-	1644232..1645206 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
V5G01_RS08615 (V5G01_08645)	rplU	1645430..1645738 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=937052 V5G01_RS08580 WP_003689814.1 1639991..1640851(+) (pilD) [Neisseria gonorrhoeae strain WHO_D_2024]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=937052 V5G01_RS08580 WP_003689814.1 1639991..1640851(+) (pilD) [Neisseria gonorrhoeae strain WHO_D_2024]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441