Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   V5G03_RS01755 Genome accession   NZ_CP145077
Coordinates   350062..352281 (+) Length   739 a.a.
NCBI ID   WP_154247499.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO_G_2024     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 345062..357281
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G03_RS01750 (V5G03_01755) - 345078..349676 (-) 4599 WP_106346851.1 S6 family peptidase -
  V5G03_RS01755 (V5G03_01760) comA 350062..352281 (+) 2220 WP_154247499.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  V5G03_RS01760 (V5G03_01765) comL 352351..353154 (-) 804 WP_003687645.1 outer membrane protein assembly factor BamD Machinery gene
  V5G03_RS01765 (V5G03_01770) rluD 353153..354277 (+) 1125 WP_003692709.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  V5G03_RS01770 (V5G03_01775) - 354430..355377 (-) 948 Protein_342 bile acid:sodium symporter family protein -
  V5G03_RS01775 (V5G03_01780) pgeF 355831..356610 (+) 780 WP_003687651.1 peptidoglycan editing factor PgeF -
  V5G03_RS01780 (V5G03_01785) lptE 356662..357141 (+) 480 WP_003687653.1 LPS assembly lipoprotein LptE -

Sequence

Protein


Download         Length: 739 a.a.        Molecular weight: 79862.64 Da        Isoelectric Point: 10.3077

>NTDB_id=936932 V5G03_RS01755 WP_154247499.1 350062..352281(+) (comA) [Neisseria gonorrhoeae strain WHO_G_2024]
MFRRWFLPCWVVGVAVSFALSVVPHWPFWLAAFAVLAVLARRFAFAGLMLCVLAGAAYGVFRTEAALSSQWRAEAVSGVP
LTVEVADMPRSDGRRVQFAAKAVDSGGRTFDLLLSDYKRREWAVGSRWRITARVHPVVGELNLRGLNREAWALSNGVGGV
GTVGADRVLLHGGSGWGIAVWRSRISRNWRQADADGGLSDGIGLMRALSVGEQSALRPELWQAFRPLGLTHLVSISGLHV
TMVAVLFAWLAKRLLACSPRLPARPRAWVLAAGCAGALFYALLAGFSVPTQRSVLMLAAFAWAWRRGRLSAWATWWQALA
AVLLFDPLAVLGVGTWLSFGLVAALIWACAGRLYEGKRQTAVRGQWAASVLSLVLLGYLFASLPLVSPLVNAVSIPWFSW
VLTPLALLGSVVPFAPLQQAGAFLAEYTLRFLVWLADVSPEFAVAAAPLPLLVLAVCAALLLLLPRGLGLRPWAVLLLAG
FVSYRPEAVPENEAAVTVWDAGQGLSVLVRTANRHLLFDTGTVAAAQTGIVPSLNAAGVRRLDKLVLSHHDSDHDGGFQA
VGKIPNGGIYAGQPEFYEGARHCAEQRWQWDGVDFEFLRPSERKNIDDNGKSCVLRVVAGGAALLVTGDLDTKGEESLVG
KYGGNLYSQVLVLGHHGSNTSSSGVFLNAVSPEYAVASSGYANAYKHPTEAVQNRVRAHGIKLLRTDLSGALQFGLGRGG
VKAQRLRVYKFYWQKKPFE

Nucleotide


Download         Length: 2220 bp        

>NTDB_id=936932 V5G03_RS01755 WP_154247499.1 350062..352281(+) (comA) [Neisseria gonorrhoeae strain WHO_G_2024]
GTGTTCCGTCGTTGGTTTTTGCCGTGTTGGGTTGTCGGCGTGGCAGTTTCGTTCGCACTGTCGGTTGTACCGCATTGGCC
GTTTTGGTTGGCGGCTTTTGCGGTTTTGGCTGTGCTTGCAAGGCGTTTTGCGTTTGCCGGTCTGATGCTGTGCGTGTTGG
CGGGCGCGGCTTACGGCGTATTCAGAACGGAAGCGGCACTGTCTTCGCAATGGCGGGCGGAGGCGGTTTCAGGCGTGCCT
TTGACGGTGGAAGTGGCGGATATGCCGAGGTCGGACGGGCGGCGCGTGCAGTTTGCGGCAAAGGCTGTGGACAGCGGCGG
TCGGACGTTTGATTTGCTGCTGTCGGACTACAAACGGCGCGAATGGGCGGTCGGGAGCAGATGGCGGATAACGGCACGCG
TGCACCCCGTCGTCGGGGAGTTGAACCTGCGCGGTTTGAACCGTGAGGCGTGGGCATTATCCAACGGGGTAGGCGGCGTG
GGGACGGTCGGTGCGGACAGGGTTTTGCTGCATGGCGGAAGCGGTTGGGGGATTGCGGTTTGGCGCAGCCGCATCAGCCG
CAATTGGCGGCAGGCGGATGCGGACGGCGGGCTTTCAGACGGCATCGGGCTGATGCGCGCGTTGAGCGTGGGCGAACAGT
CGGCATTGCGCCCCGAATTGTGGCAGGCGTTCCGGCCGTTGGGGCTGACGCATTTGGTCAGTATCTCGGGTTTGCACGTT
ACGATGGTGGCGGTGCTGTTTGCGTGGCTGGCGAAGCGGCTGCTTGCCTGTTCCCCGCGCCTTCCCGCCCGGCCGCGCGC
GTGGGTTTTGGCGGCGGGGTGTGCGGGCGCGCTGTTTTACGCGCTGCTTGCCGGTTTTTCCGTGCCGACGCAGCGCAGTG
TTTTGATGTTGGCGGCGTTCGCGTGGGCGTGGCGCAGGGGAAGACTGTCGGCGTGGGCGACGTGGTGGCAGGCGTTGGCG
GCGGTGCTGCTGTTCGACCCTTTGGCGGTTTTGGGTGTCGGTACTTGGCTGTCTTTCGGTTTGGTGGCGGCCCTGATATG
GGCGTGTGCAGGGCGTTTGTACGAGGGGAAACGGCAAACCGCCGTGCGCGGGCAGTGGGCGGCTTCGGTGTTGTCTCTGG
TTTTGCTCGGTTATCTGTTTGCCTCGCTGCCTTTGGTCAGCCCTTTGGTCAATGCGGTGTCGATACCGTGGTTTTCTTGG
GTGTTGACCCCGCTGGCGTTGCTGGGTTCGGTCGTGCCGTTTGCGCCGCTTCAGCAGGCGGGGGCATTTTTGGCGGAATA
CACTTTGCGGTTTTTGGTGTGGCTTGCCGATGTGTCGCCTGAGTTTGCCGTTGCCGCCGCACCTTTGCCGCTGCTGGTGT
TGGCGGTGTGTGCCGCTTTGCTGTTGCTGCTGCCGCGCGGCTTGGGTTTGCGTCCGTGGGCGGTGTTGCTGTTGGCAGGG
TTTGTATCCTACCGTCCTGAAGCAGTACCTGAAAACGAAGCTGCGGTTACGGTTTGGGATGCGGGGCAGGGCTTGTCGGT
GCTTGTGCGGACGGCAAACCGCCATCTGCTTTTCGATACGGGAACGGTAGCGGCGGCACAAACGGGTATCGTGCCGAGTT
TGAATGCGGCGGGTGTCCGCCGTTTGGACAAGCTGGTTCTGTCGCATCACGACAGCGACCACGACGGCGGCTTTCAGGCA
GTCGGCAAGATACCGAACGGCGGGATTTATGCCGGACAGCCGGAATTTTATGAGGGGGCGCGGCATTGTGCGGAACAGCG
TTGGCAATGGGACGGCGTGGATTTCGAGTTTTTGAGGCCGTCTGAACGCAAAAATATCGATGATAATGGGAAAAGTTGTG
TTTTGCGTGTTGTGGCGGGCGGTGCGGCACTGCTGGTAACGGGCGATTTGGATACGAAGGGCGAGGAAAGCCTGGTCGGC
AAGTATGGAGGCAACCTGTACAGCCAGGTGTTGGTGTTGGGGCATCACGGCAGCAATACGTCCTCGTCGGGCGTGTTCCT
CAATGCCGTTTCGCCCGAATATGCCGTTGCTTCAAGCGGTTATGCCAACGCCTACAAGCATCCGACCGAAGCGGTGCAGA
ACCGTGTCCGCGCACACGGCATCAAGTTGTTGCGGACGGATTTGTCGGGCGCGCTGCAATTCGGCTTGGGACGCGGAGGC
GTAAAGGCTCAACGTTTGAGAGTGTATAAATTCTATTGGCAGAAAAAACCGTTTGAGTGA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(500-677)

Competence protein (Competence)

(208-465)

Domain of unknown function (DUF4131) (DUF4131)

(7-167)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

99.729

100

0.997