Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   V5F98_RS11480 Genome accession   NZ_CP145052
Coordinates   2164848..2166101 (+) Length   417 a.a.
NCBI ID   WP_003687004.1    Uniprot ID   A0AB74EGQ8
Organism   Neisseria gonorrhoeae strain WHO_F_2024     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2159848..2171101
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5F98_RS11460 (V5F98_11475) - 2160595..2161596 (+) 1002 WP_003686999.1 thiamine ABC transporter substrate-binding protein -
  V5F98_RS11465 (V5F98_11480) - 2161690..2162538 (+) 849 WP_003687000.1 mechanosensitive ion channel family protein -
  V5F98_RS11470 (V5F98_11485) - 2162565..2163050 (+) 486 WP_003687001.1 CinA family protein -
  V5F98_RS11475 (V5F98_11490) msrAB 2163134..2164702 (-) 1569 WP_003696503.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  V5F98_RS11480 (V5F98_11495) pilA 2164848..2166101 (+) 1254 WP_003687004.1 signal recognition particle-docking protein FtsY Machinery gene
  V5F98_RS11485 (V5F98_11500) - 2166368..2167126 (-) 759 Protein_2225 opacity family porin -
  V5F98_RS11490 (V5F98_11505) pilE 2167729..2167947 (-) 219 WP_106278853.1 pilin Machinery gene
  V5F98_RS11495 (V5F98_11510) - 2167951..2168387 (-) 437 Protein_2227 pilin -
  V5F98_RS11500 (V5F98_11515) - 2168756..2168899 (-) 144 WP_047924256.1 hypothetical protein -
  V5F98_RS11505 (V5F98_11520) - 2169004..2169084 (-) 81 Protein_2229 pilin -
  V5F98_RS11510 (V5F98_11525) - 2169202..2169609 (-) 408 Protein_2230 pilin -
  V5F98_RS11515 (V5F98_11530) lpxC 2169738..2170661 (-) 924 WP_003687007.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -

Sequence

Protein


Download         Length: 417 a.a.        Molecular weight: 44389.74 Da        Isoelectric Point: 4.8123

>NTDB_id=936531 V5F98_RS11480 WP_003687004.1 2164848..2166101(+) (pilA) [Neisseria gonorrhoeae strain WHO_F_2024]
MFSFFRRKKKQETPALEEAQVQETAAKVESEVAQIVGNIKEDVESLAESVKGRAESAVETVSGAVEQVKETVAEMPSEAG
EAAERVESAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLAKSRDKMAKSLAGVFGGGQIGEDLYEELETVLIT
GDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGKLAKY
FQAQGKSVLLAAGDTFRAAAREQLQAWGGRNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHLMEEI
KKVKRVLQKAIPGAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGI
DDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1254 bp        

>NTDB_id=936531 V5F98_RS11480 WP_003687004.1 2164848..2166101(+) (pilA) [Neisseria gonorrhoeae strain WHO_F_2024]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCCCAAGTTCAGGAAACCGCAGCAAA
AGTAGAATCTGAAGTTGCTCAAATAGTTGGAAATATTAAAGAAGATGTCGAATCTTTAGCAGAAAGCGTCAAAGGGCGGG
CCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCCGTCTGAAGCAGGG
GAAGCGGCGGAACGCGTTGAATCCGCAAAAGAAGCTGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCAAGTTCAAGAAGC
CGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCTGCGCGTTTGAAACAAGGCTTGGCCAAATCACGCGACAAAATGG
CGAAATCGCTGGCCGGCGTGTTCGGCGGCGGACAAATCGGCGAGGATTTGTACGAAGAGCTGGAAACCGTGCTGATTACC
GGCGATATGGGCATGGAGGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGGGCTGAAAGACGG
CAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCGTTGGAAAAACCGCTGGTCTTGCCCGAAA
CTAAAGAGCCTTTCGTGATTATGCTTGCCGGTATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAACTCGCCAAATAT
TTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGATACCTTCCGCGCCGCCGCGCGCGAGCAGCTTCAGGCTTG
GGGCGGGCGCAACAATGTAACCGTGATTTCACAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATGCCGTCCAAGCCG
CCAAAGCGCGCGGGATCGACATCGTGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTGATGGAAGAAATC
AAAAAAGTGAAGCGCGTGCTGCAAAAAGCCATTCCCGGCGCGCCGCACGAAATTATCGTCGTACTCGATGCCAATATCGG
GCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACGGGGCTTATCGTTACCAAACTCGACGGCA
CGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGCCCCGTCCCCGTCCGCTACATCGGCGTGGGCGAAGGCATA
GACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(217-416)

SRP54-type protein, helical bundle domain (SRP54_N)

(132-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

99.76

100

0.998