Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ACEPOU_RS04350 Genome accession   NZ_CP168498
Coordinates   809320..810582 (+) Length   420 a.a.
NCBI ID   WP_000472293.1    Uniprot ID   Q6GG31
Organism   Staphylococcus aureus strain J22     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 804320..815582
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACEPOU_RS04315 (ACEPOU_04315) infC 804848..805375 (+) 528 WP_001791162.1 translation initiation factor IF-3 -
  ACEPOU_RS04320 (ACEPOU_04320) rpmI 805404..805604 (+) 201 WP_001125540.1 50S ribosomal protein L35 -
  ACEPOU_RS04325 (ACEPOU_04325) rplT 805651..806007 (+) 357 WP_001138360.1 50S ribosomal protein L20 -
  ACEPOU_RS04330 (ACEPOU_04330) - 806149..806757 (+) 609 WP_000032657.1 NUDIX domain-containing protein -
  ACEPOU_RS04335 (ACEPOU_04335) - 806776..807705 (+) 930 WP_001280010.1 hypothetical protein -
  ACEPOU_RS04340 (ACEPOU_04340) - 807710..807820 (+) 111 WP_001790560.1 hypothetical protein -
  ACEPOU_RS04345 (ACEPOU_04345) tig 807868..809169 (+) 1302 WP_000127572.1 trigger factor -
  ACEPOU_RS04350 (ACEPOU_04350) clpX 809320..810582 (+) 1263 WP_000472293.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ACEPOU_RS04355 (ACEPOU_04355) yihA 810736..811326 (+) 591 WP_000867695.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ACEPOU_RS04360 (ACEPOU_04360) hemA 811543..812889 (+) 1347 WP_000545453.1 glutamyl-tRNA reductase -
  ACEPOU_RS04365 (ACEPOU_04365) ccsA 812911..813726 (+) 816 WP_001157329.1 cytochrome c biogenesis protein -
  ACEPOU_RS04370 (ACEPOU_04370) hemC 813768..814694 (+) 927 WP_001230226.1 hydroxymethylbilane synthase -
  ACEPOU_RS04375 (ACEPOU_04375) - 814716..815384 (+) 669 WP_000805956.1 uroporphyrinogen-III synthase -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2645

>NTDB_id=936164 ACEPOU_RS04350 WP_000472293.1 809320..810582(+) (clpX) [Staphylococcus aureus strain J22]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=936164 ACEPOU_RS04350 WP_000472293.1 809320..810582(+) (clpX) [Staphylococcus aureus strain J22]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAATA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTGGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
GTTACAAAAAAGTAACATTGCCTTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACCTTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGCTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGCACAACTGCGAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGTAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6GG31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531