Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   M2038_RS00200 Genome accession   NZ_AP025693
Coordinates   47449..49065 (-) Length   538 a.a.
NCBI ID   WP_103263408.1    Uniprot ID   -
Organism   Staphylococcus aureus strain JICS127     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 39127..56099 47449..49065 within 0


Gene organization within MGE regions


Location: 39127..56099
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2038_RS00160 (JICS127ACC_0031) mecA 39127..41136 (-) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  M2038_RS00165 (JICS127ACC_0032) - 41233..42219 (+) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  M2038_RS00170 (JICS127ACC_0033) - 42191..42451 (+) 261 WP_001549961.1 type I restriction enzyme endonuclease domain-containing protein -
  M2038_RS00175 (JICS127ACC_0034) - 42716..43915 (+) 1200 WP_076035539.1 IS110-like element ISSep2 family transposase -
  M2038_RS00180 (JICS127ACC_0035) - 44011..45606 (-) 1596 Protein_33 IS1182 family transposase -
  M2038_RS00185 (JICS127ACC_0036) - 45658..46164 (-) 507 WP_001092189.1 DUF1643 domain-containing protein -
  M2038_RS00190 (JICS127ACC_0037) - 46179..46490 (-) 312 WP_000700851.1 DUF960 family protein -
  M2038_RS00195 (JICS127ACC_0039) - 46577..46927 (-) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  M2038_RS00200 (JICS127ACC_0040) ccrB 47449..49065 (-) 1617 WP_103263408.1 recombinase family protein Machinery gene
  M2038_RS00205 (JICS127ACC_0041) ccrA 49087..50436 (-) 1350 WP_000815640.1 recombinase family protein Machinery gene
  M2038_RS00210 (JICS127ACC_0042) - 50670..52457 (-) 1788 WP_000122620.1 DUF927 domain-containing protein -
  M2038_RS00215 (JICS127ACC_0043) - 52457..52747 (-) 291 WP_001036438.1 hypothetical protein -
  M2038_RS00220 (JICS127ACC_0044) - 52887..53936 (+) 1050 WP_000613248.1 hypothetical protein -
  M2038_RS00225 (JICS127ACC_0045) - 54609..56099 (+) 1491 WP_000554504.1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 538 a.a.        Molecular weight: 62151.32 Da        Isoelectric Point: 9.8656

>NTDB_id=93616 M2038_RS00200 WP_103263408.1 47449..49065(-) (ccrB) [Staphylococcus aureus strain JICS127]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRMLKDAKEGNIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAHQGNLPLG
YDKIPDSKHELMINQHEANIVKYIFECYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAKYKDW
SEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKDGTKK
RIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYDEVQI
KINNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKTLFDAKEISKLLQHIFHDIKHIEKSRLKALYL
SVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI

Nucleotide


Download         Length: 1617 bp        

>NTDB_id=93616 M2038_RS00200 WP_103263408.1 47449..49065(-) (ccrB) [Staphylococcus aureus strain JICS127]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAACAGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATCGACTGTGTTATG
GTATACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTGTCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAGATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAACGTATTTATGGGTCAAACGAGACGTGCCCATCAAGGCAATTTACCACTAGGT
TATGACAAAATACCAGATAGTAAACACGAGCTAATGATTAACCAACATGAAGCTAATATTGTAAAATATATATTCGAGTG
CTATGCCAAAGGACATGGCTATCGTAAAATTGCCAATGCATTGAATCACAAAGGATATGTCACTAAAAAGGGGAAACCTT
TCAGTATTAGTTCAATCACATACATCTTAGCTAACCCTTTCTATATCGGCAAAATTCAATTTGCGAAATACAAAGATTGG
AGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTATTAATCAAGATTT
ATGGGATAAAGTACAAATGCGTAAGAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGAATCTGCTTACAG
GCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACTCTTAAAGACGGGACTAAGAAA
CGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGTAAGAGCTGATGT
GATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAGTAACACACGTCA
ATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGATGAAGTACAAATC
AAAATAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTATTCAAAAATATGA
AAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGACTTTATTTGATGCCA
AAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAAGCATTGTATCTA
TCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAAACTTAATAACGA
AATCATTAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTATTTTTGCCCCAAACAC
TATATCTTACTATTTAG

Domains

Predicted by InterproScan.

Ogr/Delta-like zinc finger (Ogr_Delta)

(297-352)

Resolvase, N terminal domain (Resolvase)

(11-156)

Recombinase (Recombinase)

(176-276)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

97.97

100

0.987

Multiple sequence alignment