Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   V5G17_RS09425 Genome accession   NZ_CP145024
Coordinates   1799210..1800463 (-) Length   417 a.a.
NCBI ID   WP_047919725.1    Uniprot ID   A0AAX2TQK3
Organism   Neisseria gonorrhoeae strain WHO_U_2024     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1794210..1805463
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G17_RS09395 (V5G17_09415) - 1794291..1794647 (+) 357 Protein_1828 pilin -
  V5G17_RS09400 (V5G17_09420) - 1795128..1795492 (+) 365 Protein_1829 pilin -
  V5G17_RS09405 (V5G17_09430) lpxC 1796196..1797119 (+) 924 WP_003687007.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -
  V5G17_RS09410 (V5G17_09435) pilE 1797225..1797632 (+) 408 WP_171001314.1 pilin Machinery gene
  V5G17_RS09415 (V5G17_09440) - 1798261..1798941 (+) 681 WP_137655528.1 opacity family porin -
  V5G17_RS09420 (V5G17_09445) - 1798955..1799173 (+) 219 WP_171001307.1 hypothetical protein -
  V5G17_RS09425 (V5G17_09450) pilA 1799210..1800463 (-) 1254 WP_047919725.1 signal recognition particle-docking protein FtsY Machinery gene
  V5G17_RS09430 (V5G17_09455) msrAB 1800609..1802177 (+) 1569 WP_003694393.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  V5G17_RS09435 (V5G17_09460) - 1802261..1802743 (-) 483 WP_003694396.1 CinA family protein -
  V5G17_RS09440 (V5G17_09465) - 1802770..1803618 (-) 849 WP_003687000.1 mechanosensitive ion channel family protein -
  V5G17_RS09445 (V5G17_09470) - 1803712..1804713 (-) 1002 WP_003691948.1 thiamine ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 417 a.a.        Molecular weight: 44359.71 Da        Isoelectric Point: 4.8123

>NTDB_id=936041 V5G17_RS09425 WP_047919725.1 1799210..1800463(-) (pilA) [Neisseria gonorrhoeae strain WHO_U_2024]
MFSFFRRKKKQETPALEEAQVQETAAKVESEVAQIVGNIKEDVESLAESVKGRAESAVETVSGAVEQVKETVAEMPSEAG
EAAERVESAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLAKSRDKMAKSLAGVFGGGQIGEDLYEELETVLIT
GDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGKLAKY
FQAQGKSVLLAAGDTFRAAAREQLQAWGGRNNVTVISQTAGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHLMEEI
KKVKRVLQKAIPGAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGI
DDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1254 bp        

>NTDB_id=936041 V5G17_RS09425 WP_047919725.1 1799210..1800463(-) (pilA) [Neisseria gonorrhoeae strain WHO_U_2024]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCCCAAGTTCAGGAAACCGCAGCAAA
AGTAGAATCTGAAGTTGCTCAAATAGTTGGAAATATTAAAGAAGATGTCGAATCTTTAGCAGAAAGCGTCAAAGGGCGGG
CCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCCGTCTGAAGCAGGG
GAAGCGGCGGAACGCGTTGAATCCGCAAAAGAAGCTGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCAAGTTCAAGAAGC
CGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCTGCGCGTTTGAAACAAGGCTTGGCCAAATCACGCGACAAAATGG
CGAAATCGCTGGCCGGCGTGTTCGGCGGCGGACAAATCGGCGAGGATTTGTACGAAGAGCTGGAAACCGTGCTGATTACC
GGCGATATGGGCATGGAGGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGGGCTGAAAGACGG
CAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCGTTGGAAAAACCGCTGGTCTTGCCCGAAA
CTAAAGAGCCTTTCGTGATTATGCTTGCCGGTATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAACTCGCCAAATAT
TTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGATACTTTCCGCGCCGCCGCGCGCGAGCAGCTTCAGGCTTG
GGGCGGGCGCAACAATGTGACCGTGATTTCACAAACTGCGGGCGATTCCGCCGCCGTGTGCTTCGATGCCGTCCAAGCCG
CGAAAGCGCGCGGGATCGACATCGTGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTGATGGAAGAAATC
AAAAAAGTGAAGCGCGTGCTGCAAAAAGCCATTCCCGGCGCGCCGCACGAAATCATCGTCGTACTCGATGCCAATATCGG
GCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACGGGGCTTATCGTTACCAAACTCGACGGCA
CGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGCCCCGTCCCCGTCCGCTACATCGGCGTGGGCGAAGGCATA
GACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(217-416)

SRP54-type protein, helical bundle domain (SRP54_N)

(132-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

99.52

100

0.995