Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilL   Type   Machinery gene
Locus tag   V5G05_RS02700 Genome accession   NZ_CP145019
Coordinates   520265..520738 (+) Length   157 a.a.
NCBI ID   WP_025455782.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO_X_2024     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 521284..558642 520265..520738 flank 546


Gene organization within MGE regions


Location: 520265..558642
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G05_RS02700 (V5G05_02705) pilL 520265..520738 (+) 474 WP_025455782.1 PilX family type IV pilin Machinery gene
  V5G05_RS02705 (V5G05_02710) - 521350..521795 (-) 446 Protein_522 AzlC family ABC transporter permease -
  V5G05_RS02710 (V5G05_02715) dut 521961..522413 (+) 453 WP_003690909.1 dUTP diphosphatase -
  V5G05_RS02715 (V5G05_02720) dapC 522491..523678 (+) 1188 WP_003690911.1 succinyldiaminopimelate transaminase -
  V5G05_RS02720 (V5G05_02725) yaaA 523834..524613 (+) 780 WP_003690913.1 peroxide stress protein YaaA -
  V5G05_RS02735 (V5G05_02740) - 525144..526340 (+) 1197 WP_003704323.1 integrase arm-type DNA-binding domain-containing protein -
  V5G05_RS02740 (V5G05_02745) - 526696..526965 (-) 270 WP_003687928.1 hypothetical protein -
  V5G05_RS02745 (V5G05_02750) - 527160..527843 (-) 684 WP_003687929.1 DUF2786 domain-containing protein -
  V5G05_RS02750 (V5G05_02755) - 528157..528390 (-) 234 Protein_529 hypothetical protein -
  V5G05_RS02755 (V5G05_02760) - 528501..528716 (-) 216 WP_003691538.1 hypothetical protein -
  V5G05_RS02760 (V5G05_02765) - 528768..529259 (-) 492 WP_003691537.1 siphovirus Gp157 family protein -
  V5G05_RS02765 (V5G05_02770) - 529256..529438 (-) 183 WP_003691535.1 hypothetical protein -
  V5G05_RS02770 (V5G05_02775) - 529578..530264 (-) 687 WP_003691532.1 phage replication initiation protein, NGO0469 family -
  V5G05_RS02775 (V5G05_02780) - 530333..530494 (-) 162 WP_003691530.1 hypothetical protein -
  V5G05_RS02780 (V5G05_02785) - 530491..530769 (-) 279 WP_003691529.1 NGO1622 family putative holin -
  V5G05_RS02785 (V5G05_02790) - 530922..531254 (-) 333 WP_003691528.1 hypothetical protein -
  V5G05_RS02790 (V5G05_02795) - 531395..531682 (-) 288 WP_115067298.1 hypothetical protein -
  V5G05_RS02795 (V5G05_02800) - 531679..532155 (-) 477 WP_002255718.1 hypothetical protein -
  V5G05_RS02800 (V5G05_02805) - 532188..532388 (-) 201 WP_003692842.1 hypothetical protein -
  V5G05_RS02805 (V5G05_02810) - 532586..532999 (-) 414 WP_003687963.1 hypothetical protein -
  V5G05_RS02810 (V5G05_02815) - 532996..533457 (-) 462 WP_003687965.1 helix-turn-helix domain-containing protein -
  V5G05_RS02815 (V5G05_02820) - 533474..533911 (-) 438 WP_003687967.1 hypothetical protein -
  V5G05_RS02820 (V5G05_02825) - 534026..534742 (-) 717 WP_003687969.1 LexA family transcriptional regulator -
  V5G05_RS02825 (V5G05_02830) - 534811..535047 (+) 237 WP_003687971.1 Cro/CI family transcriptional regulator -
  V5G05_RS02830 (V5G05_02835) - 535127..535282 (+) 156 WP_047923772.1 hypothetical protein -
  V5G05_RS02835 (V5G05_02840) - 535259..535447 (-) 189 WP_047926457.1 hypothetical protein -
  V5G05_RS02840 (V5G05_02845) - 535621..535848 (+) 228 WP_003691442.1 helix-turn-helix domain-containing protein -
  V5G05_RS02845 (V5G05_02850) - 535845..536855 (+) 1011 WP_014580341.1 helix-turn-helix domain-containing protein -
  V5G05_RS02850 (V5G05_02855) - 536867..537646 (+) 780 WP_025455804.1 ATP-binding protein -
  V5G05_RS02855 (V5G05_02860) - 537639..537887 (+) 249 WP_106158912.1 hypothetical protein -
  V5G05_RS02860 (V5G05_02865) - 537963..538457 (+) 495 WP_003691434.1 DUF3310 domain-containing protein -
  V5G05_RS02865 (V5G05_02870) - 538634..538783 (+) 150 WP_003689110.1 hypothetical protein -
  V5G05_RS02870 (V5G05_02875) - 538812..539093 (+) 282 WP_003689109.1 hypothetical protein -
  V5G05_RS02875 (V5G05_02880) - 539084..539521 (+) 438 WP_017147288.1 RusA family crossover junction endodeoxyribonuclease -
  V5G05_RS02880 (V5G05_02885) - 539514..539819 (+) 306 WP_003687981.1 nuclease domain-containing protein -
  V5G05_RS02885 (V5G05_02890) - 539816..540199 (+) 384 WP_003690918.1 recombination protein NinB -
  V5G05_RS02890 (V5G05_02895) - 540190..540708 (+) 519 WP_003687984.1 HNH endonuclease -
  V5G05_RS02895 (V5G05_02900) - 540773..541195 (+) 423 WP_003690919.1 hypothetical protein -
  V5G05_RS02900 (V5G05_02905) - 541195..541734 (+) 540 WP_003690920.1 hypothetical protein -
  V5G05_RS02905 (V5G05_02910) - 541715..542989 (+) 1275 WP_014580143.1 PBSX family phage terminase large subunit -
  V5G05_RS02910 (V5G05_02915) - 542974..545241 (+) 2268 WP_225577699.1 hypothetical protein -
  V5G05_RS02915 (V5G05_02920) - 545478..546674 (+) 1197 WP_003690925.1 hypothetical protein -
  V5G05_RS02920 (V5G05_02925) - 546671..547885 (+) 1215 WP_047954539.1 hypothetical protein -
  V5G05_RS02925 (V5G05_02930) - 550779..553883 (+) 3105 Protein_564 PLxRFG domain-containing protein -
  V5G05_RS02930 (V5G05_02935) - 553865..554602 (+) 738 WP_003690932.1 hypothetical protein -
  V5G05_RS02935 (V5G05_02940) - 554623..555918 (+) 1296 WP_003690933.1 DUF4043 family protein -
  V5G05_RS02940 (V5G05_02945) - 555973..556446 (+) 474 WP_003690936.1 hypothetical protein -
  V5G05_RS02945 (V5G05_02950) - 556452..556937 (+) 486 WP_003687997.1 hypothetical protein -
  V5G05_RS02950 (V5G05_02955) - 556934..557608 (+) 675 WP_003687998.1 hypothetical protein -
  V5G05_RS02955 (V5G05_02960) - 557611..557760 (+) 150 WP_003706419.1 hypothetical protein -
  V5G05_RS02960 (V5G05_02965) - 557797..558642 (-) 846 WP_003690940.1 BRO family protein -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 17506.38 Da        Isoelectric Point: 9.8238

>NTDB_id=935926 V5G05_RS02700 WP_025455782.1 520265..520738(+) (pilL) [Neisseria gonorrhoeae strain WHO_X_2024]
MEQKGFTLIEMMIVVTILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNVLKQFILKNPQDNNQTIKSKLEIFVSGYKM
NPKIAKKYSVSVKFVDAEKPRVYRLVGVPNVGTGYTLSVWMNSVGDGYKCRDAASAKAYKEQLSGDGGCEALSNRKK

Nucleotide


Download         Length: 474 bp        

>NTDB_id=935926 V5G05_RS02700 WP_025455782.1 520265..520738(+) (pilL) [Neisseria gonorrhoeae strain WHO_X_2024]
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTTGTCACGATACTCGGCATCATCAGCGTCATTGCCATACC
TTCTTATCAGAGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATGTTCTCAAAC
AGTTTATTTTGAAAAATCCCCAGGACAATAATCAGACCATCAAGAGCAAACTGGAAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTAAAGTTTGTCGATGCGGAAAAACCAAGGGTATACAGGTTGGTCGG
TGTTCCGAACGTGGGGACGGGTTATACCTTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCG
CTTCGGCAAAGGCCTATAAAGAGCAGTTGTCCGGAGACGGTGGTTGTGAAGCCTTATCCAACCGTAAGAAATAG

Domains

Predicted by InterproScan.

Minor type IV pilin, PilX (Pilin_PilX)

(31-157)

Prokaryotic N-terminal methylation motif (N_methyl)

(3-25)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilL Neisseria gonorrhoeae MS11

89.172

100

0.892
  pilX Neisseria meningitidis 8013

85.987

100

0.86