Detailed information NTG0935907

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: V5G14_RS10505
• Genome accession: NZ_CP145017
• Coordinates: 2000255..2001442 (+)
• Length: 395 a.a.
• NCBI ID: WP_003690292.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain WHO_Y_2024
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1995255..2006442

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V5G14_RS10490 (V5G14_10520)	-	1996175..1996774 (+)	600	WP_003690290.1	DUF4390 domain-containing protein	-
V5G14_RS10495 (V5G14_10525)	-	1996774..1998894 (+)	2121	WP_003690126.1	HAMP domain-containing histidine kinase	-
V5G14_RS10500 (V5G14_10530)	-	1998887..2000164 (+)	1278	WP_003690124.1	sigma-54 dependent transcriptional regulator	-
V5G14_RS10505 (V5G14_10535)	dprA	2000255..2001442 (+)	1188	WP_003690292.1	DNA-processing protein DprA	Machinery gene
V5G14_RS10510 (V5G14_10540)	-	2001468..2001929 (+)	462	WP_003690120.1	DUF494 domain-containing protein	-
V5G14_RS10515 (V5G14_10545)	topA	2002007..2004313 (+)	2307	WP_003694350.1	type I DNA topoisomerase	-
V5G14_RS10520 (V5G14_10550)	-	2004534..2004662 (+)	129	Protein_2041	phosphomethylpyrimidine synthase ThiC	-
V5G14_RS10525 (V5G14_10555)	-	2004652..2005196 (+)	545	Protein_2042	IS1595 family transposase	-
V5G14_RS10530 (V5G14_10560)	-	2005297..2006106 (+)	810	WP_082286302.1	opacity family porin	-
V5G14_RS10535 (V5G14_10565)	-	2006080..2006280 (-)	201	WP_123768351.1	hypothetical protein	-

Sequence

Protein

• Length: 395 a.a.
• Molecular weight: 41880.98 Da
• Isoelectric Point: 6.3096

>NTDB_id=935907 V5G14_RS10505 WP_003690292.1 2000255..2001442(+) (dprA) [Neisseria gonorrhoeae strain WHO_Y_2024]
MTEDERFAWLQLAFTPYIGAESFLLLMRSFGSAQNALSAPAEQVAPAVRHKHALEAWRNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGRALGGKGIPTVSGMASGIDT
AAHQGALEAEGGTIAVWGTGIDRIYPPANKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLTECLDDILNECPGLLQNTGASSYSINKDTPDTGRRAVQT
AYAPPPAAKMPSEGAAGGTAVGGILDKMGFDPIHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1188 bp

>NTDB_id=935907 V5G14_RS10505 WP_003690292.1 2000255..2001442(+) (dprA) [Neisseria gonorrhoeae strain WHO_Y_2024]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGTTTCCTGCTGCTGAT
GCGCAGTTTCGGCAGCGCGCAAAATGCCTTGTCCGCACCGGCGGAACAGGTTGCCCCGGCGGTGCGGCATAAGCACGCGC
TTGAGGCTTGGCGCAATGCGGAAAAACGCGCTTTGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGCCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAGGGCGTTGGGTGGGAAAGGCATTCCTACCGTGTCGGGTATGGCTTCGGGCATCGACACC
GCCGCCCATCAGGGCGCACTGGAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACGGGCATAGACCGCATTTATCCGCC
GGCCAACAAAAACCTTGCCTATGAAATCGCCGAAAAAGGGCTGATTGTCAGCGAGTTCCCCATCGGCACGCGGCCGTATG
CCGGCAACTTTCCGCGCCGCAACCGCCTGATTGCCGCGCTGTCGCAGGTTACGCTGGTGGTCGAGGCCGCCTTGGAATCC
GGTTCGCTGATTACCGCCGGCCTGGCGGCAGAAATGGGGCGCGAAGTGATGGCGGTACCCGGTTCGATAGACAACCCCCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGAGCGAAACTGACGGAATGTTTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCGTCATATTCTATAAATAAGGATACGCCCGACACGGGCCGCCGCGCCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGGGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCCATCCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCCATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterProScan.

• DNA recombination-mediator protein A (DNA_processg_A) (79-282)

• DprA winged helix domain (DprA_WH) (341-388)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae MS11	99.747	100	0.997
dprA	Neisseria gonorrhoeae strain FA1090	99.494	100	0.995
dprA	Neisseria meningitidis strain C311	90.176	100	0.906
dprA	Neisseria meningitidis MC58	90.176	100	0.906
dprA	Vibrio cholerae strain A1552	37.28	100	0.375