Detailed information
Bioinformatically predicted
Overview
| Name | pilL | Type | Machinery gene |
| Locus tag | V5G07_RS02705 | Genome accession | NZ_CP145015 |
| Coordinates | 520113..520586 (+) | Length | 157 a.a. |
| NCBI ID | WP_025455782.1 | Uniprot ID | - |
| Organism | Neisseria gonorrhoeae strain WHO_Z_2024 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 515567..558694 | 520113..520586 | within | 0 |
Gene organization within MGE regions
Location: 515567..558694
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| V5G07_RS02680 (V5G07_02685) | dnaB | 515567..516973 (+) | 1407 | WP_003690896.1 | replicative DNA helicase | - |
| V5G07_RS02685 (V5G07_02690) | pilH | 517281..517946 (+) | 666 | WP_003690897.1 | Tfp pilus assembly protein FimT/FimU | Machinery gene |
| V5G07_RS02690 (V5G07_02695) | pilI | 517978..518586 (+) | 609 | WP_106178882.1 | type IV pilus modification protein PilV | Machinery gene |
| V5G07_RS02695 (V5G07_02700) | pilJ | 518583..519524 (+) | 942 | WP_003690899.1 | PilW family protein | Machinery gene |
| V5G07_RS02700 (V5G07_02705) | pilK | 519503..520111 (+) | 609 | WP_003690900.1 | PilX N-terminal domain-containing pilus assembly protein | Machinery gene |
| V5G07_RS02705 (V5G07_02710) | pilL | 520113..520586 (+) | 474 | WP_025455782.1 | PilX family type IV pilin | Machinery gene |
| V5G07_RS02710 (V5G07_02715) | - | 521198..521643 (-) | 446 | Protein_523 | AzlC family ABC transporter permease | - |
| V5G07_RS02715 (V5G07_02720) | dut | 521809..522261 (+) | 453 | WP_003690909.1 | dUTP diphosphatase | - |
| V5G07_RS02720 (V5G07_02725) | dapC | 522339..523526 (+) | 1188 | WP_003690911.1 | succinyldiaminopimelate transaminase | - |
| V5G07_RS02725 (V5G07_02730) | yaaA | 523682..524461 (+) | 780 | WP_003690913.1 | peroxide stress protein YaaA | - |
| V5G07_RS02740 (V5G07_02745) | - | 524992..526188 (+) | 1197 | WP_003704323.1 | integrase arm-type DNA-binding domain-containing protein | - |
| V5G07_RS02745 (V5G07_02750) | - | 526544..526813 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| V5G07_RS02750 (V5G07_02755) | - | 527008..527691 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| V5G07_RS02755 (V5G07_02760) | - | 528005..528238 (-) | 234 | Protein_530 | hypothetical protein | - |
| V5G07_RS02760 (V5G07_02765) | - | 528349..528564 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| V5G07_RS02765 (V5G07_02770) | - | 528616..529107 (-) | 492 | WP_003691537.1 | siphovirus Gp157 family protein | - |
| V5G07_RS02770 (V5G07_02775) | - | 529104..529286 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| V5G07_RS02775 (V5G07_02780) | - | 529426..530112 (-) | 687 | WP_003691532.1 | phage replication initiation protein, NGO0469 family | - |
| V5G07_RS02780 (V5G07_02785) | - | 530181..530342 (-) | 162 | WP_003691530.1 | hypothetical protein | - |
| V5G07_RS02785 (V5G07_02790) | - | 530339..530617 (-) | 279 | WP_003691529.1 | NGO1622 family putative holin | - |
| V5G07_RS02790 (V5G07_02795) | - | 530770..531102 (-) | 333 | WP_003691528.1 | hypothetical protein | - |
| V5G07_RS02795 (V5G07_02800) | - | 531243..531530 (-) | 288 | WP_144858271.1 | hypothetical protein | - |
| V5G07_RS02800 (V5G07_02805) | - | 531527..532003 (-) | 477 | WP_002255718.1 | hypothetical protein | - |
| V5G07_RS02805 (V5G07_02810) | - | 532036..532236 (-) | 201 | WP_003692842.1 | hypothetical protein | - |
| V5G07_RS02810 (V5G07_02815) | - | 532434..532847 (-) | 414 | WP_003687963.1 | hypothetical protein | - |
| V5G07_RS02815 (V5G07_02820) | - | 532844..533305 (-) | 462 | WP_003687965.1 | helix-turn-helix domain-containing protein | - |
| V5G07_RS02820 (V5G07_02825) | - | 533322..533759 (-) | 438 | WP_003687967.1 | hypothetical protein | - |
| V5G07_RS02825 (V5G07_02830) | - | 533874..534590 (-) | 717 | WP_003687969.1 | LexA family transcriptional regulator | - |
| V5G07_RS02830 (V5G07_02835) | - | 534659..534895 (+) | 237 | WP_003687971.1 | Cro/CI family transcriptional regulator | - |
| V5G07_RS02835 (V5G07_02840) | - | 534975..535130 (+) | 156 | WP_047923772.1 | hypothetical protein | - |
| V5G07_RS02840 (V5G07_02845) | - | 535107..535295 (-) | 189 | WP_047926457.1 | hypothetical protein | - |
| V5G07_RS02845 (V5G07_02850) | - | 535469..535696 (+) | 228 | WP_003691442.1 | helix-turn-helix domain-containing protein | - |
| V5G07_RS02850 (V5G07_02855) | - | 535693..536703 (+) | 1011 | WP_014580341.1 | helix-turn-helix domain-containing protein | - |
| V5G07_RS02855 (V5G07_02860) | - | 536715..537494 (+) | 780 | WP_025455804.1 | ATP-binding protein | - |
| V5G07_RS02860 (V5G07_02865) | - | 537507..537770 (+) | 264 | WP_172616934.1 | hypothetical protein | - |
| V5G07_RS02865 (V5G07_02870) | - | 537809..538303 (+) | 495 | WP_003691434.1 | DUF3310 domain-containing protein | - |
| V5G07_RS02870 (V5G07_02875) | - | 538686..538835 (+) | 150 | WP_106178740.1 | hypothetical protein | - |
| V5G07_RS02875 (V5G07_02880) | - | 538864..539145 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| V5G07_RS02880 (V5G07_02885) | - | 539136..539573 (+) | 438 | WP_017147288.1 | RusA family crossover junction endodeoxyribonuclease | - |
| V5G07_RS02885 (V5G07_02890) | - | 539566..539871 (+) | 306 | WP_003687981.1 | nuclease domain-containing protein | - |
| V5G07_RS02890 (V5G07_02895) | - | 539868..540251 (+) | 384 | WP_003690918.1 | recombination protein NinB | - |
| V5G07_RS02895 (V5G07_02900) | - | 540242..540760 (+) | 519 | WP_003687984.1 | HNH endonuclease | - |
| V5G07_RS02900 (V5G07_02905) | - | 540825..541247 (+) | 423 | WP_003690919.1 | hypothetical protein | - |
| V5G07_RS02905 (V5G07_02910) | - | 541247..541786 (+) | 540 | WP_003690920.1 | hypothetical protein | - |
| V5G07_RS02910 (V5G07_02915) | - | 541767..543041 (+) | 1275 | WP_014580143.1 | PBSX family phage terminase large subunit | - |
| V5G07_RS02915 (V5G07_02920) | - | 543026..545293 (+) | 2268 | WP_225577699.1 | hypothetical protein | - |
| V5G07_RS02920 (V5G07_02925) | - | 545530..546726 (+) | 1197 | WP_003690925.1 | hypothetical protein | - |
| V5G07_RS02925 (V5G07_02930) | - | 546723..547937 (+) | 1215 | WP_047954539.1 | hypothetical protein | - |
| V5G07_RS02930 (V5G07_02935) | - | 550831..553935 (+) | 3105 | Protein_565 | PLxRFG domain-containing protein | - |
| V5G07_RS02935 (V5G07_02940) | - | 553917..554654 (+) | 738 | WP_003690932.1 | hypothetical protein | - |
| V5G07_RS02940 (V5G07_02945) | - | 554675..555970 (+) | 1296 | WP_003690933.1 | DUF4043 family protein | - |
| V5G07_RS02945 (V5G07_02950) | - | 556025..556498 (+) | 474 | WP_003690936.1 | hypothetical protein | - |
| V5G07_RS02950 (V5G07_02955) | - | 556504..556989 (+) | 486 | WP_003687997.1 | hypothetical protein | - |
| V5G07_RS02955 (V5G07_02960) | - | 556986..557660 (+) | 675 | WP_003687998.1 | hypothetical protein | - |
| V5G07_RS02960 (V5G07_02965) | - | 557663..557812 (+) | 150 | WP_003706419.1 | hypothetical protein | - |
| V5G07_RS02965 (V5G07_02970) | - | 557849..558694 (-) | 846 | WP_003690940.1 | BRO family protein | - |
Sequence
Protein
Download Length: 157 a.a. Molecular weight: 17506.38 Da Isoelectric Point: 9.8238
>NTDB_id=935832 V5G07_RS02705 WP_025455782.1 520113..520586(+) (pilL) [Neisseria gonorrhoeae strain WHO_Z_2024]
MEQKGFTLIEMMIVVTILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNVLKQFILKNPQDNNQTIKSKLEIFVSGYKM
NPKIAKKYSVSVKFVDAEKPRVYRLVGVPNVGTGYTLSVWMNSVGDGYKCRDAASAKAYKEQLSGDGGCEALSNRKK
MEQKGFTLIEMMIVVTILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNVLKQFILKNPQDNNQTIKSKLEIFVSGYKM
NPKIAKKYSVSVKFVDAEKPRVYRLVGVPNVGTGYTLSVWMNSVGDGYKCRDAASAKAYKEQLSGDGGCEALSNRKK
Nucleotide
Download Length: 474 bp
>NTDB_id=935832 V5G07_RS02705 WP_025455782.1 520113..520586(+) (pilL) [Neisseria gonorrhoeae strain WHO_Z_2024]
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTTGTCACGATACTCGGCATCATCAGCGTCATTGCCATACC
TTCTTATCAGAGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATGTTCTCAAAC
AGTTTATTTTGAAAAATCCCCAGGACAATAATCAGACCATCAAGAGCAAACTGGAAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTAAAGTTTGTCGATGCGGAAAAACCAAGGGTATACAGGTTGGTCGG
TGTTCCGAACGTGGGGACGGGTTATACCTTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCG
CTTCGGCAAAGGCCTATAAAGAGCAGTTGTCCGGAGACGGTGGTTGTGAAGCCTTATCCAACCGTAAGAAATAG
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTTGTCACGATACTCGGCATCATCAGCGTCATTGCCATACC
TTCTTATCAGAGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATGTTCTCAAAC
AGTTTATTTTGAAAAATCCCCAGGACAATAATCAGACCATCAAGAGCAAACTGGAAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTAAAGTTTGTCGATGCGGAAAAACCAAGGGTATACAGGTTGGTCGG
TGTTCCGAACGTGGGGACGGGTTATACCTTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCG
CTTCGGCAAAGGCCTATAAAGAGCAGTTGTCCGGAGACGGTGGTTGTGAAGCCTTATCCAACCGTAAGAAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilL | Neisseria gonorrhoeae MS11 |
89.172 |
100 |
0.892 |
| pilX | Neisseria meningitidis 8013 |
85.987 |
100 |
0.86 |