Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACD268_RS08990 Genome accession   NZ_CP168299
Coordinates   1769818..1770450 (-) Length   210 a.a.
NCBI ID   WP_000698432.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain FC1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1764818..1775450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACD268_RS08965 (ACD268_08965) tig 1765851..1767134 (-) 1284 WP_000116465.1 trigger factor -
  ACD268_RS08970 (ACD268_08970) - 1767295..1767633 (-) 339 WP_001812733.1 tyrosine-type recombinase/integrase -
  ACD268_RS08975 (ACD268_08975) cbpG 1767989..1768579 (-) 591 Protein_1778 choline-binding protein CbpG -
  ACD268_RS08980 (ACD268_08980) - 1768660..1768899 (-) 240 WP_000754501.1 hypothetical protein -
  ACD268_RS08985 (ACD268_08985) - 1769049..1769755 (-) 707 Protein_1780 DNA alkylation repair protein -
  ACD268_RS08990 (ACD268_08990) vraR 1769818..1770450 (-) 633 WP_000698432.1 response regulator transcription factor Regulator
  ACD268_RS08995 (ACD268_08995) - 1770464..1771459 (-) 996 WP_000743659.1 sensor histidine kinase -
  ACD268_RS09000 (ACD268_09000) liaF 1771456..1772154 (-) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  ACD268_RS09005 (ACD268_09005) fni 1772231..1773241 (-) 1011 WP_000210617.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  ACD268_RS09010 (ACD268_09010) - 1773225..1774232 (-) 1008 WP_373381819.1 phosphomevalonate kinase -
  ACD268_RS09015 (ACD268_09015) mvaD 1774219..1775172 (-) 954 WP_000373458.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23562.04 Da        Isoelectric Point: 4.6491

>NTDB_id=935455 ACD268_RS08990 WP_000698432.1 1769818..1770450(-) (vraR) [Streptococcus pneumoniae strain FC1]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=935455 ACD268_RS08990 WP_000698432.1 1769818..1770450(-) (vraR) [Streptococcus pneumoniae strain FC1]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTAGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCATGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41