Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACD268_RS08000 Genome accession   NZ_CP168299
Coordinates   1564440..1566284 (-) Length   614 a.a.
NCBI ID   WP_001061153.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain FC1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1559440..1571284
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACD268_RS07975 (ACD268_07975) - 1559813..1560391 (-) 579 WP_000078149.1 uracil-DNA glycosylase family protein -
  ACD268_RS07980 (ACD268_07980) pepV 1560445..1561845 (-) 1401 WP_000560281.1 dipeptidase PepV -
  ACD268_RS07985 (ACD268_07985) - 1561858..1562463 (-) 606 WP_000670162.1 nitroreductase family protein -
  ACD268_RS07990 (ACD268_07990) - 1562634..1563434 (+) 801 WP_061816405.1 amino acid ABC transporter substrate-binding protein -
  ACD268_RS07995 (ACD268_07995) - 1563616..1564450 (-) 835 Protein_1582 metallophosphoesterase -
  ACD268_RS08000 (ACD268_08000) uvrC 1564440..1566284 (-) 1845 WP_001061153.1 excinuclease ABC subunit UvrC Machinery gene
  ACD268_RS08005 (ACD268_08005) - 1566324..1567025 (-) 702 WP_001267410.1 M57 family metalloprotease -
  ACD268_RS08010 (ACD268_08010) murN 1567104..1568336 (-) 1233 WP_001229512.1 peptidoglycan bridge formation alanyltransferase MurN -
  ACD268_RS08015 (ACD268_08015) murM 1568341..1569561 (-) 1221 WP_001809965.1 peptidoglycan bridge formation alanyltransferase MurM -
  ACD268_RS08020 (ACD268_08020) - 1569673..1570452 (-) 780 WP_044814630.1 alpha/beta hydrolase family protein -

Sequence

Protein


Download         Length: 614 a.a.        Molecular weight: 70421.95 Da        Isoelectric Point: 9.2208

>NTDB_id=935443 ACD268_RS08000 WP_001061153.1 1564440..1566284(-) (uvrC) [Streptococcus pneumoniae strain FC1]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKAL
VDTKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVDLSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSL
TKIKEASVDEIVEVGVPRAVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP

Nucleotide


Download         Length: 1845 bp        

>NTDB_id=935443 ACD268_RS08000 WP_001061153.1 1564440..1566284(-) (uvrC) [Streptococcus pneumoniae strain FC1]
ATGAACAACTTGATTAAATCAAAACTAGAGCTCTTGCCGACCAGCCCTGGTTGCTACATTCATAAGGATAAAAATGGCAC
CATTATCTATGTAGGAAAGGCTAAAAATCTGCGTAATCGAGTACGGTCCTATTTTCGTGGAAGTCATGATACCAAGACAG
AGGCTCTGGTGTCTGAAATTGTGGATTTTGAATTTATTGTTACGGAGTCTAATATTGAGGCACTTCTCCTAGAAATCAAC
CTGATCAAGGAAAACAAGCCCAAGTACAATATCATGCTCAAGGATGACAAGTCCTATCCTTTCATCAAAATCACCAATGA
GCGCTATCCACGCTTGATTATCACTCGTCAGGTCAAAAAGGACGGAGGTCTTTATTTTGGACCCTATCCCGATGTGGGGG
CAGCCAATGAAATCAAGCGGTTGCTGGATCGGATATTCCCTTTTCGTAAGTGTACCAACCCGCCCTCTAAGGTCTGTTTT
TATTACCATATCGGTCAATGCATGGCCCACACCATCTGTAAGAAGGATGAGACTTATTTCAAGTCTATGGCCCAGGAGGT
TTCTGATTTTCTGAAAGGGCAGGATAACAAAATCATTGATGAGCTAAAGGGCAAAATGGCAGCGGCAGCCCAGACTATGG
AGTTTGAACGTGCGGCGGAATACCGTGACCTGATTCAGGCTATTGGAACGCTTCGAACCAAGCAACGGGTCATGGCTAAG
GATCTCCAAAATCGCGATGTCTTTGGCTACTATGTGGATAAGGGCTGGATGTGTGTGCAGGTTTTCTTTGTCCGTCAGGG
TAAGCTCATCGAGCGCGATGTCAATCTCTTCCCCTACTTCAATGATCCAGATGAGGATTTTTTGACCTATGTAGGACAAT
TCTATCAAGAAAAATCTCACCTAGTTCCCAATGAGGTACTGATTCCGCAGGATATTGACGAAGAAGCTGTCAAGGCTTTG
GTGGATACCAAGATTCTCAAACCCCAACGTGGAGAGAAAAAACAGCTGGTCAATCTAGCCATAAAAAATGCACGTGTTAG
TCTGGAGCAGAAATTTAACCTGCTAGAGAAATCTGTCGAGAAGACCCAAGGAGCTATTGAAAATCTAGGACGTTTGCTCC
AAATCCCGACCCCAGTACGTATCGAGTCCTTCGATAACTCTAATATCATGGGAACTAGCCCTGTTTCGGCTATGGTGGTC
TTTGTCAACGGTAAACCGAGTAAGAAGGATTACCGCAAGTACAAGATAAAAACGGTTGTTGGACCAGACGACTATGCCAG
CATGAGAGAGGTCATTCGCAGACGCTATGGTCGAGTACAGCGTGAGGCTTTGACTCCTCCAGATTTGATTGTGATTGATG
GGGGGCAAGGTCAAGTCAATATCGCTAAGCAGGTTATCCAAGAGGAACTGGGCTTGGATATTCCAATTGCTGGGCTGCAA
AAGAATGATAAGCACCAAACCCATGAACTGCTCTTTGGAGATCCGCTTGAGGTGGTGGACTTGTCTCGCAATTCTCAGGA
ATTTTTCCTCCTCCAACGCATCCAAGATGAGGTGCACCGCTTTGCCATTACCTTCCACCGCCAACTGCGCTCCAAAAATT
CTTTCTCATCTCAATTGGATGGGATTGATGGTCTGGGACCTAAACGCAAGCAAAATCTCATGAGGCACTTCAAGTCTCTG
ACCAAAATCAAGGAAGCCAGTGTGGATGAGATTGTCGAAGTTGGAGTACCAAGAGCAGTAGCAGAGGCTGTGCAAAGAAA
GTTGAACCCGCAGGGAGAAGCCTTGCCTCAAGTAGCAGAAGAAAGAGTAGATTACCAAACGGAAGGAAACCACAATGAAC
CATAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(197-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

98.534

100

0.985
  uvrC Streptococcus pneumoniae R6

98.371

100

0.984
  uvrC Streptococcus pneumoniae D39

98.371

100

0.984