Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACD269_RS01950 Genome accession   NZ_CP168260
Coordinates   371839..372471 (+) Length   210 a.a.
NCBI ID   WP_000698432.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain FC2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 366839..377471
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACD269_RS01925 (ACD269_01925) mvaD 367116..368069 (+) 954 WP_000373457.1 diphosphomevalonate decarboxylase -
  ACD269_RS01930 (ACD269_01930) - 368056..369063 (+) 1008 WP_061366143.1 phosphomevalonate kinase -
  ACD269_RS01935 (ACD269_01935) fni 369047..370057 (+) 1011 WP_000210617.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  ACD269_RS01940 (ACD269_01940) liaF 370135..370833 (+) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  ACD269_RS01945 (ACD269_01945) - 370830..371825 (+) 996 WP_000743680.1 sensor histidine kinase -
  ACD269_RS01950 (ACD269_01950) vraR 371839..372471 (+) 633 WP_000698432.1 response regulator transcription factor Regulator
  ACD269_RS01955 (ACD269_01955) - 372472..372714 (+) 243 Protein_382 DNA alkylation repair protein -
  ACD269_RS01960 (ACD269_01960) - 372639..373241 (+) 603 Protein_383 DNA alkylation repair protein -
  ACD269_RS01965 (ACD269_01965) - 373391..373630 (+) 240 WP_000754501.1 hypothetical protein -
  ACD269_RS01970 (ACD269_01970) cbpG 373711..374301 (+) 591 Protein_385 choline-binding protein CbpG -
  ACD269_RS01975 (ACD269_01975) - 374657..374995 (+) 339 WP_001812733.1 tyrosine-type recombinase/integrase -
  ACD269_RS01980 (ACD269_01980) tig 375156..376439 (+) 1284 WP_000116465.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23562.04 Da        Isoelectric Point: 4.6491

>NTDB_id=935193 ACD269_RS01950 WP_000698432.1 371839..372471(+) (vraR) [Streptococcus pneumoniae strain FC2]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=935193 ACD269_RS01950 WP_000698432.1 371839..372471(+) (vraR) [Streptococcus pneumoniae strain FC2]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGATAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTTAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTCGGGCATGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41