Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ACCK16_RS08150 Genome accession   NZ_CP168089
Coordinates   1693929..1695191 (-) Length   420 a.a.
NCBI ID   WP_000472293.1    Uniprot ID   Q6GG31
Organism   Staphylococcus aureus strain CUBIST-23     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1688929..1700191
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACCK16_RS08125 (ACCK16_08125) - 1689127..1689795 (-) 669 WP_000805953.1 uroporphyrinogen-III synthase -
  ACCK16_RS08130 (ACCK16_08130) hemC 1689817..1690743 (-) 927 WP_001230218.1 hydroxymethylbilane synthase -
  ACCK16_RS08135 (ACCK16_08135) ccsA 1690785..1691600 (-) 816 WP_001157329.1 cytochrome c biogenesis protein -
  ACCK16_RS08140 (ACCK16_08140) hemA 1691622..1692968 (-) 1347 WP_000545465.1 glutamyl-tRNA reductase -
  ACCK16_RS08145 (ACCK16_08145) yihA 1693185..1693775 (-) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ACCK16_RS08150 (ACCK16_08150) clpX 1693929..1695191 (-) 1263 WP_000472293.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ACCK16_RS08155 (ACCK16_08155) tig 1695342..1696643 (-) 1302 WP_000127567.1 trigger factor -
  ACCK16_RS08160 (ACCK16_08160) - 1696691..1696801 (-) 111 WP_001790560.1 hypothetical protein -
  ACCK16_RS08165 (ACCK16_08165) - 1696806..1697735 (-) 930 WP_372487103.1 hypothetical protein -
  ACCK16_RS08170 (ACCK16_08170) - 1697754..1698362 (-) 609 WP_000032657.1 NUDIX domain-containing protein -
  ACCK16_RS08175 (ACCK16_08175) rplT 1698504..1698860 (-) 357 WP_001138360.1 50S ribosomal protein L20 -
  ACCK16_RS08180 (ACCK16_08180) rpmI 1698907..1699107 (-) 201 WP_001125540.1 50S ribosomal protein L35 -
  ACCK16_RS08185 (ACCK16_08185) infC 1699136..1699663 (-) 528 WP_001807711.1 translation initiation factor IF-3 -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2645

>NTDB_id=934366 ACCK16_RS08150 WP_000472293.1 1693929..1695191(-) (clpX) [Staphylococcus aureus strain CUBIST-23]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=934366 ACCK16_RS08150 WP_000472293.1 1693929..1695191(-) (clpX) [Staphylococcus aureus strain CUBIST-23]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTGGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCCTTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACAACTGCAAGTGTTCCACCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGCCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGATGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACTCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGTAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6GG31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531