Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ACCK22_RS09650 Genome accession   NZ_CP168085
Coordinates   1908852..1910114 (-) Length   420 a.a.
NCBI ID   WP_000472302.1    Uniprot ID   P63789
Organism   Staphylococcus aureus strain CUBIST-27     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1903852..1915114
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACCK22_RS09625 (ACCK22_09625) - 1904050..1904718 (-) 669 WP_000805951.1 uroporphyrinogen-III synthase -
  ACCK22_RS09630 (ACCK22_09630) hemC 1904740..1905666 (-) 927 WP_001230232.1 hydroxymethylbilane synthase -
  ACCK22_RS09635 (ACCK22_09635) ccsA 1905708..1906523 (-) 816 WP_001157329.1 cytochrome c biogenesis protein -
  ACCK22_RS09640 (ACCK22_09640) hemA 1906545..1907891 (-) 1347 WP_000545451.1 glutamyl-tRNA reductase -
  ACCK22_RS09645 (ACCK22_09645) yihA 1908108..1908698 (-) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ACCK22_RS09650 (ACCK22_09650) clpX 1908852..1910114 (-) 1263 WP_000472302.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ACCK22_RS09655 (ACCK22_09655) - 1910298..1911617 (+) 1320 WP_001557163.1 ISL3-like element IS1181 family transposase -
  ACCK22_RS09660 (ACCK22_09660) tig 1911785..1913086 (-) 1302 WP_000127579.1 trigger factor -
  ACCK22_RS09665 (ACCK22_09665) - 1913134..1913244 (-) 111 WP_001790560.1 hypothetical protein -
  ACCK22_RS09670 (ACCK22_09670) - 1913249..1914178 (-) 930 WP_001280022.1 hypothetical protein -
  ACCK22_RS09675 (ACCK22_09675) - 1914197..1914805 (-) 609 WP_000032657.1 NUDIX domain-containing protein -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46297.48 Da        Isoelectric Point: 4.2645

>NTDB_id=934191 ACCK22_RS09650 WP_000472302.1 1908852..1910114(-) (clpX) [Staphylococcus aureus strain CUBIST-27]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=934191 ACCK22_RS09650 WP_000472302.1 1908852..1910114(-) (clpX) [Staphylococcus aureus strain CUBIST-27]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATGACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTAGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCATTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGCAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63789

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531