Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AB9M03_RS05640 Genome accession   NZ_CP168035
Coordinates   1117714..1118370 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain EC23HZZ201     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1112714..1123370
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB9M03_RS05610 (AB9M03_05610) yecA 1113965..1114630 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  AB9M03_RS05630 (AB9M03_05630) pgsA 1115280..1115828 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AB9M03_RS05635 (AB9M03_05635) uvrC 1115885..1117717 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  AB9M03_RS05640 (AB9M03_05640) letA 1117714..1118370 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AB9M03_RS05645 (AB9M03_05645) - 1118512..1118628 (+) 117 WP_001302039.1 hypothetical protein -
  AB9M03_RS05650 (AB9M03_05650) yecU 1118666..1118842 (+) 177 WP_001307856.1 protein YecU -
  AB9M03_RS05655 (AB9M03_05655) yecF 1118829..1119053 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  AB9M03_RS05660 (AB9M03_05660) sdiA 1119121..1119843 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  AB9M03_RS05665 (AB9M03_05665) tcyN 1120073..1120825 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AB9M03_RS05670 (AB9M03_05670) tcyL 1120822..1121490 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  AB9M03_RS05675 (AB9M03_05675) dcyD 1121505..1122491 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=934059 AB9M03_RS05640 WP_000611335.1 1117714..1118370(-) (letA) [Escherichia coli strain EC23HZZ201]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=934059 AB9M03_RS05640 WP_000611335.1 1117714..1118370(-) (letA) [Escherichia coli strain EC23HZZ201]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486