Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Machinery gene
Locus tag   V3I11_RS08375 Genome accession   NZ_CP144280
Coordinates   1659953..1660459 (-) Length   168 a.a.
NCBI ID   WP_011272049.1    Uniprot ID   Q4QNA7
Organism   Haemophilus influenzae strain P3_EMO     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1654953..1665459
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V3I11_RS08345 (V3I11_08345) nudC 1655446..1656240 (-) 795 WP_005686893.1 NAD(+) diphosphatase -
  V3I11_RS08350 (V3I11_08350) nfuA 1656307..1656903 (-) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  V3I11_RS08355 (V3I11_08355) - 1656979..1657665 (-) 687 WP_011272045.1 ComF family protein -
  V3I11_RS08360 (V3I11_08360) comE 1657678..1659015 (-) 1338 WP_011272046.1 type IV pilus secretin PilQ Machinery gene
  V3I11_RS08365 (V3I11_08365) comD 1659025..1659438 (-) 414 WP_011272047.1 pilus assembly protein PilP Machinery gene
  V3I11_RS08370 (V3I11_08370) comC 1659435..1659956 (-) 522 WP_011272048.1 competence protein ComC Machinery gene
  V3I11_RS08375 (V3I11_08375) comB 1659953..1660459 (-) 507 WP_011272049.1 competence protein ComB Machinery gene
  V3I11_RS08380 (V3I11_08380) comA 1660460..1661257 (-) 798 WP_011272050.1 pilus assembly protein PilM Machinery gene
  V3I11_RS08385 (V3I11_08385) - 1661356..1663950 (+) 2595 WP_042593320.1 penicillin-binding protein 1A -
  V3I11_RS08390 (V3I11_08390) - 1664023..1664868 (+) 846 WP_011272052.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  V3I11_RS08395 (V3I11_08395) - 1665037..1665366 (+) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -

Sequence

Protein


Download         Length: 168 a.a.        Molecular weight: 19697.54 Da        Isoelectric Point: 7.4684

>NTDB_id=933316 V3I11_RS08375 WP_011272049.1 1659953..1660459(-) (comB) [Haemophilus influenzae strain P3_EMO]
MSMNLLPWRTYQHQKRLRRLAFYIALFILLAINLMLAFSNLIEQQKQNLQAQQTSFEQLNQQLHKTTMQIDQLRSAVKVG
EVLTSIPNEQVKKSLQQLSELPFQQGELNKFKQDANNLSLEGNAQDQTEFELIHQFLKKHFPNVKLSQVQPEQDTLFFHF
DVEQGAEK

Nucleotide


Download         Length: 507 bp        

>NTDB_id=933316 V3I11_RS08375 WP_011272049.1 1659953..1660459(-) (comB) [Haemophilus influenzae strain P3_EMO]
ATGTCGATGAATTTATTGCCTTGGCGTACTTATCAACATCAAAAGCGTTTACGTCGTTTAGCTTTTTATATCGCTTTATT
TATCTTGCTTGCTATTAATTTAATGTTGGCTTTTAGCAATTTGATTGAACAACAGAAACAAAATTTGCAAGCGCAGCAAA
CATCTTTTGAACAACTTAATCAGCAACTTCACAAAACTACCATGCAAATTGATCAGTTACGCAGTGCGGTGAAAGTTGGT
GAAGTTTTGACATCTATTCCCAACGAGCAAGTAAAAAAGAGTTTACAACAGCTAAGTGAATTACCTTTTCAACAAGGAGA
ACTGAATAAATTTAAACAAGATGCCAATAACTTAAGTTTGGAAGGTAACGCGCAAGATCAAACAGAATTTGAACTGATTC
ATCAATTTTTAAAGAAACATTTTCCCAATGTGAAATTAAGTCAGGTTCAACCTGAACAAGATACATTGTTTTTTCACTTT
GATGTGGAACAAGGGGCGGAAAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QNA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Haemophilus influenzae 86-028NP

100

100

1
  comB Haemophilus influenzae Rd KW20

98.81

100

0.988