Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC   Type   Machinery gene
Locus tag   V3I11_RS08370 Genome accession   NZ_CP144280
Coordinates   1659435..1659956 (-) Length   173 a.a.
NCBI ID   WP_011272048.1    Uniprot ID   Q4QNA8
Organism   Haemophilus influenzae strain P3_EMO     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1654435..1664956
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V3I11_RS08340 (V3I11_08340) - 1654820..1655410 (-) 591 WP_005686892.1 YjaG family protein -
  V3I11_RS08345 (V3I11_08345) nudC 1655446..1656240 (-) 795 WP_005686893.1 NAD(+) diphosphatase -
  V3I11_RS08350 (V3I11_08350) nfuA 1656307..1656903 (-) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  V3I11_RS08355 (V3I11_08355) - 1656979..1657665 (-) 687 WP_011272045.1 ComF family protein -
  V3I11_RS08360 (V3I11_08360) comE 1657678..1659015 (-) 1338 WP_011272046.1 type IV pilus secretin PilQ Machinery gene
  V3I11_RS08365 (V3I11_08365) comD 1659025..1659438 (-) 414 WP_011272047.1 pilus assembly protein PilP Machinery gene
  V3I11_RS08370 (V3I11_08370) comC 1659435..1659956 (-) 522 WP_011272048.1 competence protein ComC Machinery gene
  V3I11_RS08375 (V3I11_08375) comB 1659953..1660459 (-) 507 WP_011272049.1 competence protein ComB Machinery gene
  V3I11_RS08380 (V3I11_08380) comA 1660460..1661257 (-) 798 WP_011272050.1 pilus assembly protein PilM Machinery gene
  V3I11_RS08385 (V3I11_08385) - 1661356..1663950 (+) 2595 WP_042593320.1 penicillin-binding protein 1A -
  V3I11_RS08390 (V3I11_08390) - 1664023..1664868 (+) 846 WP_011272052.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -

Sequence

Protein


Download         Length: 173 a.a.        Molecular weight: 19994.18 Da        Isoelectric Point: 10.0952

>NTDB_id=933315 V3I11_RS08370 WP_011272048.1 1659435..1659956(-) (comC) [Haemophilus influenzae strain P3_EMO]
MKAFFNDPFTPFGKWLSQPFYVHGLTFLLLLSAVIFRPVLDYIEGSSRFHEIENELAVKRSELLHQQKILTSLQQQSESR
KLSPELAAQIIPLNKQIQRLAARNGLSQHLRWEMGQKPILHLQLTGHFEKTKTFLTALLANSSQLSVSRLQFIKPEDNPL
QTEIIFQLDKETK

Nucleotide


Download         Length: 522 bp        

>NTDB_id=933315 V3I11_RS08370 WP_011272048.1 1659435..1659956(-) (comC) [Haemophilus influenzae strain P3_EMO]
ATGAAAGCTTTTTTTAACGATCCTTTTACTCCTTTTGGAAAATGGCTAAGTCAGCCTTTTTATGTGCACGGTTTAACCTT
TTTATTGCTATTAAGTGCGGTGATTTTTCGCCCCGTTTTAGATTATATCGAGGGGAGTTCACGTTTCCATGAAATTGAAA
ATGAGTTAGCGGTGAAACGTTCAGAATTGTTGCATCAACAGAAAATTTTAACTTCTTTACAGCAGCAGTCGGAAAGTCGA
AAACTTTCTCCAGAACTGGCTGCACAAATTATTCCTTTGAATAAACAAATTCAACGTTTAGCTGCGCGTAACGGTTTATC
TCAGCATTTACGTTGGGAAATGGGGCAAAAGCCTATTTTGCATTTACAGCTTACAGGTCATTTTGAGAAAACGAAGACAT
TTTTAACCGCACTTTTGGCTAATTCGTCACAGCTTTCAGTGAGTCGCTTGCAGTTTATCAAACCCGAAGACAACCCATTG
CAAACCGAGATCATTTTTCAGCTAGATAAGGAAACAAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QNA8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Haemophilus influenzae 86-028NP

100

100

1
  comC Haemophilus influenzae Rd KW20

98.266

100

0.983