Detailed information NTG0933062

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: ACDW35_RS10290
• Genome accession: NZ_CP167983
• Coordinates: 2206871..2209096 (+)
• Length: 741 a.a.
• NCBI ID: WP_003138588.1
• Uniprot ID: A0A0H2ZCX3
• Organism: Pseudomonas aeruginosa strain 0102d1_7
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2201871..2214096

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACDW35_RS10265 (ACDW35_10265)	-	2202177..2202776 (-)	600	WP_016254241.1	PilZ domain-containing protein	-
ACDW35_RS10270 (ACDW35_10270)	-	2202879..2204129 (+)	1251	WP_003091170.1	lipoprotein-releasing ABC transporter permease subunit	-
ACDW35_RS10275 (ACDW35_10275)	lolD	2204122..2204805 (+)	684	WP_003109474.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
ACDW35_RS10280 (ACDW35_10280)	-	2204875..2206119 (+)	1245	WP_003105198.1	lipoprotein-releasing ABC transporter permease subunit	-
ACDW35_RS10285 (ACDW35_10285)	-	2206207..2206740 (-)	534	WP_003091165.1	DUF2062 domain-containing protein	-
ACDW35_RS10290 (ACDW35_10290)	comA	2206871..2209096 (+)	2226	WP_003138588.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACDW35_RS10295 (ACDW35_10295)	exbB	2209169..2209804 (+)	636	WP_003091163.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
ACDW35_RS10300 (ACDW35_10300)	-	2209801..2210241 (+)	441	WP_003091161.1	biopolymer transporter ExbD	-
ACDW35_RS10305 (ACDW35_10305)	lpxK	2210241..2211239 (+)	999	WP_003091159.1	tetraacyldisaccharide 4'-kinase	-
ACDW35_RS10310 (ACDW35_10310)	-	2211277..2211462 (+)	186	WP_003091157.1	Trm112 family protein	-
ACDW35_RS10315 (ACDW35_10315)	kdsB	2211462..2212226 (+)	765	WP_003130694.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
ACDW35_RS10320 (ACDW35_10320)	-	2212226..2212690 (+)	465	WP_003138590.1	low molecular weight protein-tyrosine-phosphatase	-
ACDW35_RS10325 (ACDW35_10325)	murB	2212687..2213706 (+)	1020	WP_003119807.1	UDP-N-acetylmuramate dehydrogenase	-

Sequence

Protein

• Length: 741 a.a.
• Molecular weight: 79970.55 Da
• Isoelectric Point: 10.4652

>NTDB_id=933062 ACDW35_RS10290 WP_003138588.1 2206871..2209096(+) (comA) [Pseudomonas aeruginosa strain 0102d1_7]
MRLGLPALAAGLLALRFLAELPSVGWLLGMAAAGLLLLFGRLYWLGLFLLGFAWACGSAQVALDGRLAAELDGRTLWLEG
RVVDLPASGEGVTRFRLEEVSAARGVLLPERLRLSWRGAPPLMGGERWRLAVTLKRPRGLVNAAGFDYEAWLLAQRVGAV
GKVKAGQRLQPASGLDAWRDAWRQRLLAVDAQGRGAALAALVLGDGSGLSAAEWRMFQDTGTVHLMVISGSHISLLAGML
YGLVAALHRLGCWPRRLPWLPCACALGLLGAWSYGLMAGFEVPVRRACLMVSLALVWRLRFRHLGLLTPLLATLVLVLLV
EPLASLQAGFWLSFLAVALLLWLFAGRLGRWRWWAAWGRAQWGMALGLAMPLLALGLPLSLSGAPANLLAVPWIELLVVP
PALAGSLLLWVPGLGEGLLRAAGVSLDLLFRALGLLAGLAEAWQPPAAAAWSVALGMLGALCWLAPAGLPLRALGAALLL
PALLPSSPPVEWGRAEVRVLDVGQGLAVLVRTREHALLYDSGARQGAFDMGERVVVPVLRSLDLRRLDGLLLSHADNDHA
GGAPTVASRFPPGWLVSGEPARLPSPLFADSCDERSWSWDGVVFEQWAWAQAGDSNDRSCVLRVEADGEVLLLTGDISRA
AEHAWLARQADPRVDWLLAPHHGSRSSSGVAFVLRTRPRHVLVSRGWRNAFGHPHGEVMERYARVAAQVHDTARDGALTF
FLGSRGGARRERDSAHFWREK

Nucleotide

• Length: 2226 bp

>NTDB_id=933062 ACDW35_RS10290 WP_003138588.1 2206871..2209096(+) (comA) [Pseudomonas aeruginosa strain 0102d1_7]
ATGCGCCTGGGATTGCCAGCCCTCGCCGCGGGGCTGCTGGCCCTGCGCTTCCTGGCGGAATTGCCGTCGGTCGGCTGGCT
GCTGGGCATGGCCGCCGCCGGACTGTTGCTGCTGTTCGGCCGGCTGTACTGGCTGGGGTTGTTCCTGCTCGGGTTCGCCT
GGGCCTGCGGCTCGGCGCAAGTCGCCCTGGACGGACGCCTGGCCGCCGAGCTGGATGGTCGCACCCTTTGGCTGGAGGGG
CGTGTGGTCGATCTGCCGGCGAGCGGCGAGGGCGTCACGCGCTTCCGGCTGGAGGAGGTCAGCGCTGCGCGGGGCGTGCT
TCTTCCCGAGCGTCTGCGCCTGAGCTGGCGCGGCGCGCCGCCGCTGATGGGCGGCGAACGCTGGCGCCTGGCGGTGACCC
TGAAACGCCCCCGCGGCCTGGTGAACGCGGCGGGTTTCGACTACGAGGCCTGGTTGTTGGCGCAGCGGGTCGGTGCTGTG
GGCAAGGTGAAGGCGGGCCAACGCCTGCAGCCGGCCAGCGGCCTGGATGCCTGGCGCGATGCCTGGCGCCAGCGCCTGCT
GGCGGTCGACGCACAGGGGCGCGGCGCCGCCCTGGCGGCGCTGGTGCTGGGGGATGGCTCGGGATTGAGCGCGGCCGAGT
GGCGAATGTTCCAGGACACCGGCACCGTGCATCTGATGGTCATCTCCGGTTCGCATATCTCGTTGCTGGCGGGGATGCTC
TATGGCCTGGTGGCGGCCTTGCATCGCCTGGGCTGCTGGCCGCGGCGCCTGCCCTGGCTGCCCTGTGCCTGCGCCCTGGG
TTTGCTTGGTGCCTGGAGCTACGGGTTGATGGCGGGTTTCGAGGTCCCGGTGCGGCGTGCTTGCCTGATGGTCAGCCTGG
CGCTGGTCTGGCGCCTGCGTTTCCGCCACCTGGGCTTGCTGACCCCGCTGCTGGCAACGCTGGTGCTGGTCTTGCTGGTC
GAGCCGCTGGCCAGCCTGCAGGCGGGGTTCTGGCTGTCGTTCCTGGCGGTTGCCCTGCTGCTCTGGCTGTTCGCCGGGCG
CCTTGGGCGCTGGCGCTGGTGGGCGGCCTGGGGGCGGGCGCAGTGGGGGATGGCGCTGGGGCTGGCGATGCCGCTGCTGG
CGCTGGGCCTGCCGTTGAGCCTGAGCGGAGCGCCGGCCAACCTGCTGGCGGTGCCTTGGATCGAACTGCTGGTAGTGCCC
CCGGCCCTGGCGGGGAGCCTGCTGCTATGGGTGCCCGGGCTGGGCGAGGGGCTGCTTCGCGCCGCTGGCGTTTCGCTGGA
CCTGCTGTTTCGTGCGCTTGGCCTGCTGGCGGGCCTGGCCGAGGCCTGGCAGCCACCCGCCGCAGCGGCCTGGAGCGTAG
CGCTGGGCATGCTCGGCGCGCTCTGCTGGCTGGCGCCGGCTGGCTTGCCGTTGCGTGCCCTCGGTGCCGCGTTGCTACTG
CCGGCGTTGTTGCCGTCATCGCCGCCTGTCGAATGGGGGCGGGCGGAAGTGCGGGTGCTGGACGTCGGCCAGGGGCTGGC
CGTGCTGGTGCGTACCCGGGAGCATGCCTTGCTCTATGACAGCGGTGCGCGGCAGGGGGCGTTCGACATGGGCGAGCGGG
TGGTGGTGCCGGTGCTGCGCAGCCTGGACCTGCGGCGCCTGGACGGCCTGTTGCTGAGCCATGCCGACAACGACCATGCA
GGCGGTGCTCCTACGGTCGCTTCCCGATTCCCGCCGGGTTGGCTGGTCAGCGGCGAACCCGCGCGCCTGCCTTCGCCGTT
GTTCGCGGACAGCTGCGACGAGCGGAGCTGGTCCTGGGATGGCGTGGTTTTCGAACAGTGGGCATGGGCGCAGGCCGGCG
ACAGCAACGACCGCTCCTGTGTGCTGAGGGTCGAGGCCGATGGCGAAGTCCTGCTGCTGACCGGGGACATCTCGCGTGCG
GCCGAGCATGCCTGGCTGGCGCGACAGGCCGATCCCCGGGTCGACTGGTTGCTGGCGCCGCATCATGGCAGCCGCAGTTC
CTCCGGAGTCGCCTTCGTGTTGCGTACGCGACCTCGCCATGTGCTGGTCTCGCGAGGTTGGCGCAACGCCTTCGGCCATC
CCCATGGCGAAGTGATGGAGCGTTACGCGAGGGTCGCCGCGCAGGTCCACGACACGGCACGCGACGGTGCCCTGACGTTT
TTCCTCGGAAGCCGTGGCGGCGCACGCCGGGAGCGTGATTCGGCGCACTTCTGGCGGGAAAAATGA

Domains

Predicted by InterProScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (501-666)

• Domain of unknown function (DUF4131) (DUF4131) (21-168)

• Competence protein (Competence) (201-464)

3D structure

• AlphaFold DB: A0A0H2ZCX3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	58.946	97.301	0.574
comA	Ralstonia pseudosolanacearum GMI1000	35.611	100	0.366