Detailed information NTG0931428

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: ACB327_RS08220
• Genome accession: NZ_CP167020
• Coordinates: 1676754..1679309 (-)
• Length: 851 a.a.
• NCBI ID: WP_076639531.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 6
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1671754..1684309

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB327_RS08200 (ACB327_08200)	-	1672244..1672804 (-)	561	WP_002992183.1	DNA-3-methyladenine glycosylase I	-
ACB327_RS08205 (ACB327_08205)	ruvA	1672814..1673410 (-)	597	WP_002992186.1	Holliday junction branch migration protein RuvA	Machinery gene
ACB327_RS08210 (ACB327_08210)	-	1673412..1674632 (-)	1221	WP_076639530.1	MFS transporter	-
ACB327_RS08215 (ACB327_08215)	hexB	1674643..1676625 (-)	1983	WP_002992189.1	DNA mismatch repair endonuclease MutL	Machinery gene
ACB327_RS08220 (ACB327_08220)	hexA	1676754..1679309 (-)	2556	WP_076639531.1	DNA mismatch repair protein MutS	Machinery gene
ACB327_RS08225 (ACB327_08225)	-	1679296..1679662 (-)	367	Protein_1558	YlbF family regulator	-
ACB327_RS08230 (ACB327_08230)	argR	1679659..1680096 (-)	438	WP_002993102.1	arginine repressor	-
ACB327_RS08235 (ACB327_08235)	argS	1680387..1682078 (+)	1692	WP_002991367.1	arginine--tRNA ligase	-
ACB327_RS08240 (ACB327_08240)	-	1682166..1682474 (+)	309	WP_002991370.1	bacteriocin immunity protein	-
ACB327_RS08245 (ACB327_08245)	-	1682501..1683373 (-)	873	WP_002982164.1	YitT family protein	-
ACB327_RS08250 (ACB327_08250)	-	1683416..1684294 (-)	879	WP_002991372.1	YitT family protein	-

Sequence

Protein

• Length: 851 a.a.
• Molecular weight: 95532.10 Da
• Isoelectric Point: 4.9853

>NTDB_id=931428 ACB327_RS08220 WP_076639531.1 1676754..1679309(-) (hexA) [Streptococcus pyogenes strain Isolate 6]
MAKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLI
ELGYKVAVAEQMEDPKQAVGVVKREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELTAAGKLLQYVHKTQMRELSHLQA
LVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLYWLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFI
ERTDLSNSLKGVYDIERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFNSPCVDKLVNDIDSLPELEYLIRTAIDP
DAPATISEGSIIRTGFDERLDHYRKVMREGTGWIADIEAKERQASGINNLKIDYNKKDGYYFHVTTSNLSLVPEHFFRKA
TLKNSERYGTAELAKIEGQMLEAREESSSLEYDIFMCIRAQVETYINRLQKLAKTLATVDVLQSLAVIAETNHYIRPQFN
DNHVITIQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADHVDLPLFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDELGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHEL
TDLSTKLTSLVNVHVATLEKDGDVTFLHKIAEGPADKSYGIHVAKIAGLPKSLLKRADEVLTRLETQSRSTEIISVPSQV
ESSSAVRQEQLSLFGDEEKAHEIRQALEVIDVMNMTPLQAMTTLYELKKLL

Nucleotide

• Length: 2556 bp

>NTDB_id=931428 ACB327_RS08220 WP_076639531.1 1676754..1679309(-) (hexA) [Streptococcus pyogenes strain Isolate 6]
ATGGCAAAAACTAACATTTCTCCTGGAATGCAACAGTATCTGGACATCAAAAAAGATTATCCAGATGCTTTTTTGCTTTT
TAGGATGGGTGACTTTTATGAATTATTTTACGAGGACGCTGTCAAAGCAGCACAACTCTTAGAAATTGGTTTGACCAGTC
GCAACAAGAATGCGGAAAATCCAATTCCCATGGCAGGCGTGCCACATCATTCTGCCCAACAATACATTGATGTGTTAATT
GAGTTGGGTTACAAGGTTGCTGTCGCAGAACAAATGGAAGACCCAAAGCAAGCTGTTGGGGTGGTGAAGCGTGAGGTCGT
TCAAGTCATAACTCCTGGAACGGTTGTGGATTCAGCTAAGCCAGATAGCGCCAATAACTTTTTGGTAGCTGTTGACTTTG
ATGGTTGCCGTTATGGATTGGCTTATATGGATGTATCCACAGGTGAATTTTGCGTGACAGATTTGGCGGACTTTACGAGT
GTTCGTAGCGAAATCCAAAACCTCAAGGCAAAAGAAGTCTTACTAGGTTTTGATTTATCTGAAGAAGAACAGACGATTTT
GGTCAAGCAGATGAATTTGCTGCTTTCTTATGAAGAAACGGTCTATGAAGATAAATCTTTAATTGACGGCCAATTGACAA
CGGTAGAACTCACAGCGGCAGGAAAACTCTTGCAATACGTTCACAAAACACAAATGCGAGAACTCAGCCACTTGCAAGCC
TTGGTTCACTATGAGATCAAGGATTATTTGCAGATGTCGTATGCCACTAAGTCAAGTTTAGATTTGGTAGAAAATGCTAG
GACTAATAAAAAACATGGAAGTCTGTATTGGCTTTTAGATGAAACCAAGACAGCTATGGGGATGAGGCTTTTGCGCTCAT
GGATTGATCGACCTTTGGTTTCTAAAGAAGCTATTTTAGAGCGTCAAGAAATTATTCAAGTTTTTCTGAATGCTTTTATT
GAGCGAACCGATTTAAGCAATAGTTTAAAAGGTGTTTACGACATCGAACGCTTATCTAGTCGCGTGTCTTTTGGCAAGGC
AAATCCGAAAGATTTACTTCAATTGGGGCATACCTTAGCCCAAGTGCCTTATATCAAAGCTATCTTAGAGTCTTTTAACA
GTCCTTGTGTTGACAAACTTGTCAATGATATTGACAGTTTGCCTGAGTTGGAATACTTGATTAGAACAGCCATTGATCCA
GATGCACCAGCAACTATTAGTGAAGGCAGTATTATTCGTACTGGTTTTGATGAGCGCTTGGACCATTATCGTAAAGTGAT
GCGAGAAGGAACAGGCTGGATTGCGGATATTGAGGCTAAAGAGCGTCAAGCAAGCGGCATTAATAATCTAAAAATTGATT
ACAATAAAAAAGATGGATATTATTTCCACGTTACGACTTCAAATCTTAGCTTAGTGCCTGAGCATTTTTTCAGAAAGGCA
ACTTTAAAAAATTCTGAACGTTATGGAACAGCAGAATTGGCTAAGATTGAAGGTCAGATGTTAGAGGCTAGGGAAGAGTC
ATCTAGTTTAGAATACGATATTTTTATGTGTATTCGAGCTCAAGTTGAAACCTATATTAATCGTTTACAGAAACTGGCTA
AAACTTTGGCAACGGTGGATGTTTTGCAAAGTTTAGCAGTCATTGCTGAAACCAATCATTATATCCGGCCGCAGTTCAAT
GATAATCATGTGATTACAATTCAAGAAGGTCGTCACGCGGTTGTTGAAAAGGTTATGGGAGTGCAGGAATACATTCCCAA
TAGTATCTCTTTTGACCAACAGACCAGTATTCAGCTGATTACAGGTCCAAATATGAGTGGTAAGTCGACTTATATGAGAC
AGCTGGCCTTAACGGTTATCATGGCCCAGATGGGTTCATTTGTGGCTGCTGACCATGTTGATTTACCTTTATTTGATGCG
ATTTTTACGCGTATTGGGGCTGCTGATGATTTGATTTCTGGGCAATCAACCTTTATGGTGGAGATGATGGAAGCAAACCA
AGCAATCAAACGCGCAAGTGACAACTCTCTTATTCTATTTGATGAACTGGGACGAGGTACGGCAACTTATGATGGTATGG
CTTTAGCCCAGGCAATTATTGAATATATCCATGATAGAGTTGGTGCTAAGACCATATTTGCAACGCATTATCATGAATTG
ACAGACTTGTCAACTAAGTTGACAAGTCTAGTCAATGTTCATGTAGCAACGCTTGAAAAAGATGGCGATGTTACCTTCCT
TCATAAGATTGCTGAGGGACCGGCGGATAAATCTTACGGTATTCATGTGGCAAAAATAGCAGGACTGCCAAAATCCCTAT
TAAAGAGAGCAGACGAAGTTCTGACCCGTTTAGAAACACAGTCACGATCTACTGAGATAATATCAGTCCCTTCACAAGTT
GAGTCAAGCAGCGCTGTTAGACAGGAGCAATTATCCCTTTTTGGTGATGAAGAGAAAGCTCATGAGATTAGGCAAGCACT
GGAAGTTATTGATGTCATGAACATGACCCCGCTTCAAGCAATGACAACCCTTTACGAATTGAAAAAGTTGTTATAG

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (256-546)

• MutS family domain IV (MutS_IV) (415-506)

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	71.445	100	0.714
mutS	Pseudomonas stutzeri strain ATCC 17587	37.193	100	0.374