Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/comEC   Type   Machinery gene
Locus tag   MWM16_RS10085 Genome accession   NZ_AP025617
Coordinates   1842209..1844242 (+) Length   677 a.a.
NCBI ID   WP_244341018.1    Uniprot ID   -
Organism   Thermus thermophilus strain SNM7-6     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1837209..1849242
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MWM16_RS10050 (TthSNM76_19680) - 1837986..1838450 (+) 465 WP_011229049.1 hypothetical protein -
  MWM16_RS10055 (TthSNM76_19690) pfkA 1838427..1839395 (-) 969 WP_011173968.1 6-phosphofructokinase -
  MWM16_RS10060 (TthSNM76_19700) rsmI 1839392..1840186 (-) 795 WP_244341015.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  MWM16_RS10065 (TthSNM76_19710) - 1840188..1840682 (-) 495 WP_244344593.1 TFIIB-type zinc ribbon-containing protein -
  MWM16_RS10070 (TthSNM76_19720) - 1840745..1841272 (-) 528 WP_011173971.1 inorganic diphosphatase -
  MWM16_RS10075 (TthSNM76_19730) - 1841305..1841931 (+) 627 WP_011173972.1 YcxB family protein -
  MWM16_RS10080 (TthSNM76_19740) comEA 1841904..1842212 (+) 309 WP_024119555.1 helix-hairpin-helix domain-containing protein Machinery gene
  MWM16_RS10085 (TthSNM76_19750) comA/comEC 1842209..1844242 (+) 2034 WP_244341018.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  MWM16_RS10090 (TthSNM76_19760) - 1844230..1845039 (-) 810 WP_024119553.1 ParB/RepB/Spo0J family partition protein -
  MWM16_RS10095 (TthSNM76_19770) soj 1845023..1845772 (-) 750 WP_011173976.1 chromosome-partitioning ATPase Soj -
  MWM16_RS10100 (TthSNM76_19780) rsmG 1845766..1846515 (-) 750 WP_203971383.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -

Sequence

Protein


Download         Length: 677 a.a.        Molecular weight: 71868.95 Da        Isoelectric Point: 10.1641

>NTDB_id=93074 MWM16_RS10085 WP_244341018.1 1842209..1844242(+) (comA/comEC) [Thermus thermophilus strain SNM7-6]
MRPSWTWGVGLGAGALVAAWGLFAPWAFLGLGLLPFLRLPFALGFGLVLARALLFPLPEPPWGAAVEGVFAVRGGFTRAE
GHLLWVSHYPPLPDGRYRLRGRIAPPQGRTNPGGFDQRAWLLSRGAKGVLRAESAEPLGPLPDWREGFRERLGAGLSLEA
REVVEGLVLGDKGGLETAYPLFQRAGLAHLLALSGLHVGVLVGFAVLGLYPLGRWRYLLALALLPFYLLLAGPSPSLVRA
SLMAGLSLLGLFLGLGGAGVVQALGLALFLQLLLRPEALLGLGFQLSYLAVLGLALVLPALRLPPGPRGYLLGGVAASLA
VQAFLLPLLLHRFGFAPLLAPLANLLALPLVALLVPLGFLKLFLGALPAPLVEPLARGLLLLAGLAAQGPLLRWGEIAPP
GFALYYLGLLPLLFALHRRLPWRRALLLASLPALVGLLAARPKPLDLWMLDVGQGDALLARMGGGEVLVDGGRAEKGEAV
VRALRALGVEALELLVATHPDADHYGGLFRVIEEVPVGLALLAPGFPEDHPLAQALRARGVPVVRAGAGTRLKVGQGEVR
VLWPEALSGDDNQDGLALLLDFGRGRALLLADLPREVEARLPVGEVEALKVSHHGSQSGTSEVLLERTRPRVALIGVGPN
PFGHPHPEVLERLERHGAEVRRTDQDGAVRVLFGYAW

Nucleotide


Download         Length: 2034 bp        

>NTDB_id=93074 MWM16_RS10085 WP_244341018.1 1842209..1844242(+) (comA/comEC) [Thermus thermophilus strain SNM7-6]
ATGAGGCCTTCTTGGACCTGGGGAGTGGGGCTTGGGGCGGGGGCTTTGGTGGCCGCCTGGGGGCTTTTCGCGCCTTGGGC
CTTCCTTGGGCTCGGCCTCCTTCCCTTCCTCCGCCTTCCCTTCGCCCTGGGCTTCGGCCTCGTCCTGGCCCGGGCCCTCC
TCTTCCCCTTGCCCGAGCCCCCGTGGGGCGCCGCCGTGGAGGGGGTCTTCGCCGTGAGGGGCGGGTTCACACGGGCGGAG
GGCCACCTCCTCTGGGTGAGCCACTATCCCCCTCTACCGGACGGCCGCTACCGCCTCCGGGGGCGCATCGCCCCGCCCCA
AGGCCGGACCAACCCCGGGGGGTTTGACCAACGGGCCTGGCTCCTGAGCCGGGGGGCCAAGGGGGTGCTCCGGGCCGAAA
GCGCCGAGCCATTGGGGCCCCTGCCCGACTGGAGGGAGGGGTTCCGGGAACGCCTAGGGGCGGGCCTGAGCCTCGAGGCC
CGGGAGGTGGTGGAGGGCCTGGTCCTCGGGGACAAGGGGGGCTTAGAGACGGCCTACCCCCTCTTCCAGCGGGCGGGCCT
CGCCCACCTCCTGGCGCTTTCCGGCCTTCACGTGGGGGTGCTCGTGGGCTTCGCCGTCCTCGGCCTCTACCCCCTGGGGC
GGTGGCGCTACCTCCTGGCCCTCGCCCTCCTCCCCTTCTACCTCCTCCTCGCCGGGCCGAGCCCCTCCCTGGTGCGGGCG
AGCCTCATGGCGGGCCTGTCCCTCCTCGGCCTCTTCCTGGGCCTTGGGGGGGCCGGGGTGGTCCAGGCCCTGGGGCTCGC
CCTCTTCCTCCAGCTCCTCCTCCGCCCCGAGGCCCTCCTCGGCCTCGGGTTCCAGCTCTCCTACCTCGCGGTGCTGGGCC
TGGCCCTGGTCCTCCCGGCCCTGAGGCTTCCCCCGGGCCCCAGGGGCTATCTCCTCGGGGGCGTGGCCGCAAGCCTGGCC
GTCCAGGCCTTCCTCCTCCCCCTCCTCCTCCACCGCTTCGGCTTCGCCCCCCTCCTCGCCCCCCTCGCCAACCTCCTCGC
CCTCCCCCTGGTGGCCCTCCTCGTTCCCCTCGGCTTCCTCAAGCTCTTCCTCGGCGCCCTCCCCGCCCCCCTGGTGGAGC
CCCTCGCCCGGGGGCTCCTCCTCCTGGCGGGGCTTGCGGCCCAAGGGCCCCTCCTCCGCTGGGGGGAGATCGCCCCCCCA
GGCTTTGCCCTCTACTACCTGGGCCTTCTCCCCCTCCTTTTCGCCCTCCACCGCAGGCTTCCCTGGCGGCGCGCCCTCCT
CCTCGCCTCCCTGCCCGCCCTGGTGGGCCTCCTCGCCGCCCGGCCCAAGCCGCTGGACCTCTGGATGCTGGACGTGGGCC
AGGGGGACGCCCTCCTCGCCCGCATGGGGGGCGGGGAGGTCCTGGTGGACGGGGGACGGGCGGAGAAGGGGGAGGCGGTG
GTCCGGGCCCTCCGCGCCCTCGGGGTGGAGGCCCTGGAGCTTTTGGTGGCCACCCACCCCGACGCGGACCACTACGGGGG
GCTTTTCCGGGTGATAGAGGAGGTTCCCGTGGGCCTTGCCCTCCTCGCCCCCGGCTTCCCCGAGGACCACCCCCTGGCCC
AGGCCCTAAGGGCGCGGGGCGTCCCCGTGGTGCGGGCCGGGGCGGGAACCCGCCTTAAGGTGGGCCAGGGCGAGGTCCGG
GTGCTCTGGCCCGAGGCCCTCTCCGGGGACGACAACCAAGACGGCCTCGCCCTCCTCCTGGACTTCGGCCGGGGACGGGC
CCTCCTCCTCGCCGACCTGCCCCGGGAGGTGGAGGCCAGGCTTCCCGTGGGGGAGGTGGAGGCGCTCAAGGTGAGCCACC
ACGGCTCCCAAAGCGGCACCTCTGAGGTCCTCCTGGAAAGGACGAGGCCCCGGGTGGCCCTCATCGGGGTGGGGCCCAAC
CCCTTCGGCCACCCCCACCCCGAGGTCCTGGAGCGCCTTGAGCGCCACGGCGCGGAGGTACGCCGCACCGACCAGGACGG
GGCGGTGCGCGTCCTCTTCGGCTACGCCTGGTAG

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(93-136)

Metallo-beta-lactamase superfamily (Lactamase_B)

(451-635)

Competence protein (Competence)

(167-418)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/comEC Thermus thermophilus HB27

99.409

100

0.994
  comEC Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

41.013

90.399

0.371

Multiple sequence alignment