Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/comEC   Type   Machinery gene
Locus tag   MWM13_RS10690 Genome accession   NZ_AP025609
Coordinates   1965720..1967753 (+) Length   677 a.a.
NCBI ID   WP_244347698.1    Uniprot ID   -
Organism   Thermus thermophilus strain SNM3-3     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1960720..1972753
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MWM13_RS10655 (TthSNM33_21030) - 1961497..1961961 (+) 465 WP_011229049.1 hypothetical protein -
  MWM13_RS10660 (TthSNM33_21040) pfkA 1961938..1962906 (-) 969 WP_011173968.1 6-phosphofructokinase -
  MWM13_RS10665 (TthSNM33_21050) rsmI 1962903..1963697 (-) 795 WP_244347696.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  MWM13_RS10670 (TthSNM33_21060) - 1963699..1964193 (-) 495 WP_244347697.1 TFIIB-type zinc ribbon-containing protein -
  MWM13_RS10675 (TthSNM33_21070) - 1964256..1964783 (-) 528 WP_011173971.1 inorganic diphosphatase -
  MWM13_RS10680 (TthSNM33_21080) - 1964816..1965442 (+) 627 WP_011173972.1 YcxB family protein -
  MWM13_RS10685 (TthSNM33_21090) comEA 1965415..1965723 (+) 309 WP_024119555.1 helix-hairpin-helix domain-containing protein Machinery gene
  MWM13_RS10690 (TthSNM33_21100) comA/comEC 1965720..1967753 (+) 2034 WP_244347698.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  MWM13_RS10695 (TthSNM33_21110) - 1967741..1968550 (-) 810 WP_024119553.1 ParB/RepB/Spo0J family partition protein -
  MWM13_RS10700 (TthSNM33_21120) soj 1968534..1969283 (-) 750 WP_011173976.1 chromosome-partitioning ATPase Soj -
  MWM13_RS10705 (TthSNM33_21130) rsmG 1969277..1970026 (-) 750 WP_203971383.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -

Sequence

Protein


Download         Length: 677 a.a.        Molecular weight: 71880.96 Da        Isoelectric Point: 10.0614

>NTDB_id=93026 MWM13_RS10690 WP_244347698.1 1965720..1967753(+) (comA/comEC) [Thermus thermophilus strain SNM3-3]
MRPSWTWGVGLGAGALVAAWGLFAPWAFLGLGLLPFLRLPFALGFGLVLARALLFPLPEPPWGAAVEGVFAVRGGFTRAE
GHLLWVSHYPPLPDGRYRLRGRIAPPQGRTNPGGFDQRAWLLSRGAKGVLRAESAEPLGPLPDWREGFRERLGAGLSLEA
REVVEGLVLGDKGGLETAYPLFQRAGLAHLLALSGLHVGVLVGFAVLGLYPLGRWRYLLALALLPFYLLLAGPSPSLVRA
SLMAGLSLLGLFLGLGGAGVVQALGLALFLQLLLRPEALLGLGFQLSYLAVLGLALVLPALRLPPGPRGYLLGGVAASLA
VQAFLLPLLLHRFGFAPLLAPLANLLALPLVALLVPLGFLKLFLGALPAPLVEPLARGLLLLAGLAAQGPLLRWGEIAPP
GFALYYLGLLPLLFALHRRLPWRRALLLATLPALASLLAAWPKPLDLWMLDVGQGDALLARMGGGEVLVDGGRAEKGEAV
VRALRALGVEALELLVATHPDADHYGGLLRVIEEVPVGLALLAPGFPEDHPLAQALRARGVPVVRAGAGTRLKVGQGEVR
VLWPEALSGDDNQDGLALLLDFGRGRALLLADLPREVEARLPVGEVEALKVSHHGSQSGTSEVLLERTRPRVALIGVGPN
PFGHPHPEVLERLERHGAEVRRTDQDGAVRVLFGYAW

Nucleotide


Download         Length: 2034 bp        

>NTDB_id=93026 MWM13_RS10690 WP_244347698.1 1965720..1967753(+) (comA/comEC) [Thermus thermophilus strain SNM3-3]
ATGAGGCCTTCTTGGACCTGGGGAGTGGGGCTTGGGGCGGGGGCTTTGGTGGCCGCCTGGGGGCTTTTCGCGCCTTGGGC
CTTCCTTGGGCTCGGCCTCCTTCCCTTCCTCCGCCTTCCCTTCGCCCTGGGCTTCGGCCTCGTCCTGGCCCGGGCCCTCC
TCTTCCCCTTGCCCGAGCCCCCGTGGGGCGCCGCCGTGGAGGGGGTCTTCGCCGTGAGGGGCGGGTTCACACGGGCGGAG
GGCCACCTCCTCTGGGTGAGCCACTATCCCCCTCTACCGGACGGCCGCTACCGCCTCCGGGGGCGCATCGCCCCGCCCCA
AGGCCGGACCAACCCCGGGGGGTTTGACCAACGGGCCTGGCTCCTGAGCCGGGGGGCCAAGGGGGTGCTCCGGGCCGAAA
GCGCCGAGCCCTTGGGGCCCCTGCCCGACTGGAGGGAGGGGTTCCGGGAACGCCTAGGGGCGGGCCTGAGCCTCGAGGCC
CGGGAGGTGGTGGAGGGCCTGGTCCTCGGGGACAAGGGGGGCTTAGAGACGGCCTACCCCCTCTTCCAGCGGGCGGGCCT
CGCCCACCTCCTGGCGCTTTCCGGCCTTCACGTGGGGGTGCTTGTGGGCTTCGCCGTCCTCGGCCTCTACCCCCTGGGGC
GGTGGCGCTACCTCCTGGCCCTCGCCCTCCTCCCCTTCTACCTCCTCCTCGCCGGGCCGAGCCCCTCCCTGGTGCGGGCG
AGCCTCATGGCGGGCCTGTCCCTCCTCGGCCTCTTCCTGGGCCTTGGGGGGGCCGGGGTGGTCCAGGCCCTGGGGCTCGC
CCTCTTCCTCCAGCTCCTCCTCCGCCCCGAGGCCCTCCTCGGCCTCGGGTTCCAGCTCTCCTACCTCGCGGTGCTGGGCC
TGGCCCTGGTCCTCCCGGCCCTGAGGCTTCCCCCGGGCCCCAGGGGCTATCTCCTCGGGGGCGTGGCCGCAAGCCTGGCC
GTCCAGGCCTTCCTCCTCCCCCTCCTCCTCCACCGCTTCGGCTTCGCCCCCCTCCTCGCCCCCCTCGCCAACCTCCTCGC
CCTCCCCCTGGTGGCCCTCCTCGTGCCCCTCGGCTTCCTCAAGCTCTTCCTCGGCGCCCTCCCCGCCCCCCTGGTGGAGC
CCCTCGCCCGGGGGCTCCTCCTCCTGGCGGGGCTTGCGGCCCAAGGGCCCCTCCTCCGCTGGGGGGAGATCGCCCCCCCA
GGCTTTGCCCTCTACTACCTGGGCCTTCTCCCCCTCCTTTTCGCCCTCCACCGCAGGCTTCCCTGGCGGCGCGCCCTCCT
CCTCGCCACGCTTCCCGCCCTGGCGAGCCTCCTCGCCGCCTGGCCCAAGCCGCTGGACCTCTGGATGCTGGACGTGGGCC
AGGGGGACGCCCTCCTCGCCCGCATGGGGGGCGGGGAGGTCCTGGTGGACGGGGGACGGGCGGAGAAGGGGGAGGCGGTG
GTCCGGGCCCTCCGCGCCCTCGGGGTGGAGGCCCTGGAGCTTTTGGTGGCCACCCACCCCGACGCGGACCACTACGGGGG
GCTTCTCCGGGTGATAGAGGAGGTTCCCGTGGGCCTTGCCCTCCTCGCCCCCGGCTTCCCCGAGGACCACCCCCTGGCCC
AGGCCCTAAGGGCGCGGGGCGTCCCCGTGGTGCGGGCCGGGGCGGGAACCCGCCTTAAGGTGGGCCAGGGCGAGGTCCGG
GTGCTCTGGCCCGAGGCCCTCTCCGGGGACGACAACCAAGACGGCCTCGCCCTCCTCCTGGACTTCGGCCGGGGACGGGC
CCTCCTCCTCGCCGACCTGCCCCGGGAGGTGGAGGCCAGGCTTCCCGTGGGGGAGGTGGAGGCGCTCAAGGTGAGCCACC
ACGGCTCCCAAAGCGGCACCTCTGAGGTCCTCCTGGAAAGGACGAGGCCCCGGGTGGCCCTCATCGGGGTGGGGCCCAAC
CCCTTCGGCCACCCCCACCCCGAGGTCCTGGAGCGCCTTGAGCGCCACGGCGCGGAGGTACGCCGCACCGACCAGGACGG
GGCGGTGCGCGTCCTCTTCGGCTACGCCTGGTAG

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(93-136)

Metallo-beta-lactamase superfamily (Lactamase_B)

(451-635)

Competence protein (Competence)

(167-418)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/comEC Thermus thermophilus HB27

98.966

100

0.99
  comEC Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

41.176

90.399

0.372

Multiple sequence alignment