Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   U4D54_RS11420 Genome accession   NZ_CP143639
Coordinates   2321692..2322276 (-) Length   194 a.a.
NCBI ID   WP_011276196.1    Uniprot ID   A0A2A1KAP4
Organism   Staphylococcus haemolyticus strain M81.1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 2313595..2321057 2321692..2322276 flank 635


Gene organization within MGE regions


Location: 2313595..2322276
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U4D54_RS11370 (U4D54_11370) - 2313600..2315268 (-) 1669 Protein_2205 IS1182 family transposase -
  U4D54_RS11375 (U4D54_11375) - 2315541..2316143 (-) 603 WP_011276203.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  U4D54_RS11380 (U4D54_11380) - 2316160..2316336 (-) 177 WP_011276202.1 YkvS family protein -
  U4D54_RS11385 (U4D54_11385) - 2316537..2317526 (+) 990 WP_033079857.1 lipoate--protein ligase -
  U4D54_RS11390 (U4D54_11390) - 2317574..2317675 (-) 102 WP_076684686.1 Ltp family lipoprotein -
  U4D54_RS11395 (U4D54_11395) - 2317745..2318320 (-) 576 WP_033079858.1 hypothetical protein -
  U4D54_RS11400 (U4D54_11400) - 2318355..2318864 (-) 510 WP_033079859.1 PH domain-containing protein -
  U4D54_RS11405 (U4D54_11405) - 2319389..2321057 (-) 1669 Protein_2212 IS1182 family transposase -
  U4D54_RS11420 (U4D54_11420) comK/comK1 2321692..2322276 (-) 585 WP_011276196.1 competence protein ComK Regulator

Sequence

Protein


Download         Length: 194 a.a.        Molecular weight: 23002.43 Da        Isoelectric Point: 9.2942

>NTDB_id=930187 U4D54_RS11420 WP_011276196.1 2321692..2322276(-) (comK/comK1) [Staphylococcus haemolyticus strain M81.1]
MTNISQSQNTVYIIRKGDMIIKPVIDDYEQTKGSEIWKYDSTIVSSPFKTQKIVERSCKFYGNSYISKKSETQRIAGITS
KPPILLTPLFPTYFFPTHSDRLEENMWINMHYVHEIKPLKNRKCKIIFANHQTLTLNVSYHSIWHQYSNCIFYYYMVDKQ
SRMKSNNPEMPIDYEKTTLNIFEALSHYSLLQDK

Nucleotide


Download         Length: 585 bp        

>NTDB_id=930187 U4D54_RS11420 WP_011276196.1 2321692..2322276(-) (comK/comK1) [Staphylococcus haemolyticus strain M81.1]
ATGACAAATATTTCTCAAAGCCAAAATACTGTATATATTATTCGAAAAGGAGATATGATAATCAAACCCGTCATTGATGA
TTATGAGCAAACAAAAGGATCAGAAATATGGAAATATGATTCCACAATAGTTTCAAGCCCATTCAAAACTCAAAAAATCG
TCGAACGCTCATGTAAATTTTATGGTAATAGCTATATTAGTAAGAAATCCGAAACACAACGAATTGCCGGCATTACTAGT
AAACCACCTATTTTATTGACTCCTCTCTTCCCCACTTATTTTTTCCCTACACATTCAGACCGTTTAGAAGAAAACATGTG
GATTAATATGCATTATGTACATGAAATTAAACCTCTTAAAAATCGAAAATGTAAAATTATTTTTGCAAATCATCAAACAT
TAACACTTAATGTTTCCTACCACAGTATTTGGCACCAATACTCTAACTGCATTTTTTATTATTACATGGTCGATAAACAA
TCTCGTATGAAGTCAAACAATCCAGAAATGCCAATAGATTATGAGAAAACGACTTTAAATATTTTCGAAGCACTTTCACA
TTATTCACTATTACAAGATAAATAG

Domains

Predicted by InterproScan.

ComK protein (ComK)

(11-161)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2A1KAP4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

68.617

96.907

0.665
  comK/comK1 Staphylococcus aureus N315

68.617

96.907

0.665