Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGE   Type   Machinery gene
Locus tag   ACB360_RS00615 Genome accession   NZ_CP167006
Coordinates   98213..98497 (+) Length   94 a.a.
NCBI ID   WP_002987779.1    Uniprot ID   A0A0H2USY2
Organism   Streptococcus pyogenes strain Isolate 26     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 93213..103497
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB360_RS00590 (ACB360_00590) - 95159..95524 (+) 366 WP_002986560.1 DUF1033 family protein -
  ACB360_RS00595 (ACB360_00595) comGA 95617..96555 (+) 939 WP_002987773.1 competence type IV pilus ATPase ComGA Machinery gene
  ACB360_RS00600 (ACB360_00600) comGB 96491..97525 (+) 1035 WP_223845212.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACB360_RS00605 (ACB360_00605) comGC 97527..97853 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  ACB360_RS00610 (ACB360_00610) comGD 97828..98256 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACB360_RS00615 (ACB360_00615) comGE 98213..98497 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACB360_RS00620 (ACB360_00620) comGF 98490..98924 (+) 435 WP_002987783.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACB360_RS00625 (ACB360_00625) comGG 98908..99234 (+) 327 WP_002987787.1 competence type IV pilus minor pilin ComGG -
  ACB360_RS00630 (ACB360_00630) comGH 99332..100285 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  ACB360_RS00635 (ACB360_00635) - 100344..101540 (+) 1197 WP_002987791.1 acetate kinase -
  ACB360_RS00640 (ACB360_00640) - 101727..102035 (+) 309 WP_011284425.1 hypothetical protein -
  ACB360_RS00645 (ACB360_00645) proC 102118..102888 (-) 771 WP_002986527.1 pyrroline-5-carboxylate reductase -

Sequence


Protein


Download         Length: 94 a.a.        Molecular weight: 10672.62 Da        Isoelectric Point: 8.9043

>NTDB_id=930126 ACB360_RS00615 WP_002987779.1 98213..98497(+) (comGE) [Streptococcus pyogenes strain Isolate 26]
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=930126 ACB360_RS00615 WP_002987779.1 98213..98497(+) (comGE) [Streptococcus pyogenes strain Isolate 26]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATTGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAC
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0H2USY2

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383