Detailed information NTG0930045

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: VP472_RS12350
• Genome accession: NZ_CP143632
• Coordinates: 2536843..2539194 (-)
• Length: 783 a.a.
• NCBI ID: WP_146277191.1
• Uniprot ID: -
• Organism: Bacillus sp. MT(2024)
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2531843..2544194

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VP472_RS12315 (VP472_12315)	-	2532206..2532544 (-)	339	WP_007408270.1	YqxA family protein	-
VP472_RS12320 (VP472_12320)	-	2532561..2533754 (-)	1194	WP_013352939.1	stage II sporulation protein P	-
VP472_RS12325 (VP472_12325)	gpr	2533822..2534928 (-)	1107	WP_146277187.1	GPR endopeptidase	-
VP472_RS12330 (VP472_12330)	rpsT	2535131..2535397 (+)	267	WP_003152876.1	30S ribosomal protein S20	-
VP472_RS12335 (VP472_12335)	holA	2535414..2536455 (-)	1042	Protein_2382	DNA polymerase III subunit delta	-
VP472_RS12340 (VP472_12340)	-	2536495..2536649 (-)	155	Protein_2383	hypothetical protein	-
VP472_RS12345 (VP472_12345)	-	2536690..2536824 (+)	135	WP_003152870.1	YqzM family protein	-
VP472_RS12350 (VP472_12350)	comEC	2536843..2539194 (-)	2352	WP_146277191.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
VP472_RS12355 (VP472_12355)	-	2539195..2539764 (-)	570	WP_003152868.1	ComE operon protein 2	-
VP472_RS12360 (VP472_12360)	comEA	2539831..2540445 (-)	615	WP_146277193.1	helix-hairpin-helix domain-containing protein	Machinery gene
VP472_RS12365 (VP472_12365)	comER	2540504..2541325 (+)	822	WP_146277195.1	late competence protein ComER	-
VP472_RS12370 (VP472_12370)	-	2541394..2542131 (-)	738	WP_014305450.1	class I SAM-dependent methyltransferase	-
VP472_RS12375 (VP472_12375)	rsfS	2542128..2542484 (-)	357	WP_003152864.1	ribosome silencing factor	-
VP472_RS12380 (VP472_12380)	yqeK	2542502..2543062 (-)	561	WP_032856887.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
VP472_RS12385 (VP472_12385)	-	2543052..2543621 (-)	570	WP_003152860.1	nicotinate-nucleotide adenylyltransferase	-
VP472_RS12390 (VP472_12390)	yhbY	2543632..2543922 (-)	291	WP_003152858.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 783 a.a.
• Molecular weight: 86786.72 Da
• Isoelectric Point: 8.8956

>NTDB_id=930045 VP472_RS12350 WP_146277191.1 2536843..2539194(-) (comEC) [Bacillus sp. MT(2024)]
MKYKYLLLPLAAVSATAGIAAAHVFWVLLLFLLYLLFIMIKTKQPAPVVVCLVSFCVYFFLYTVCDAANVTRYQAGSYTE
QAVITNIPKVDGAKMSAVIRTHDKEKWAASYKIRSLEEKRLIEQLEPGMRCTFTGSLEQPAHATIPGGFDYKEYLYSQQI
HWLFSVTSIEQCEKSKQPLFKLLNFRKNLISIIRNHVPESSAGIVEALTLGERFSIEDDILSAYQNLGVVHLMAISGMHV
GLITAGLFYALIRIGLTREKAGMLLLLFLPVYTLLSGAAPSVLRASLMLGFYIAGTLVKRGIHSSAALSLSYLLLLLFNP
YFLWQAGFQLSFAVSASLILSSSILKKAGKSRLAGLAMASFIAELSSLPFLLYHFQQISLVSFPMNMVMVPFYTLFVIPV
SVIGFLLLLLSRQMGECLFDMFDLVMKPVHDFITYAASVDLFTMIVSKPDFLSLLLLAVSVFTLFAALEKGGFLKLRKSA
LFFCAVLAYLICRPYFSPWGEADMLDIGQGDSLFISAPYRKGTVMVDTGGVIAYPGESWKEKRHPYSIGEKVLIPFLNGK
GVKKLDALFLTHADQDHIGEAGVLIKNHRVKRLIVPVGFVKEPKDQNILKMAKENNIPVAEAKRGDTITAGDLQFQVLSP
ESSDGKSKNDSSLVLWTVLGGVSWLLTGDLESDGETEVLKTYPKLKADILKAGHHGSKSSTSEAFLKQLQPEAALISAGK
ENRYHHPHEEVLDRLKAYSVNVLRTDISGTIQYRFEKGAGTFSVFPPYDIEETRAQEVKKTAD

Nucleotide

• Length: 2352 bp

>NTDB_id=930045 VP472_RS12350 WP_146277191.1 2536843..2539194(-) (comEC) [Bacillus sp. MT(2024)]
ATGAAATATAAATACCTTCTTCTGCCTCTGGCGGCGGTTTCTGCAACTGCGGGAATTGCCGCCGCTCATGTCTTCTGGGT
TCTGCTCCTTTTTCTTCTGTATCTTCTCTTTATTATGATAAAAACAAAGCAGCCTGCTCCGGTTGTTGTCTGCCTCGTTT
CTTTTTGTGTTTATTTCTTTCTTTATACGGTTTGTGACGCTGCGAATGTAACGCGGTATCAGGCCGGCAGTTATACTGAA
CAGGCCGTCATCACTAATATTCCGAAGGTTGACGGAGCGAAAATGTCAGCCGTTATCCGTACACATGACAAGGAAAAATG
GGCGGCTTCGTATAAAATCCGGTCTCTTGAGGAAAAGAGACTCATTGAACAGCTTGAACCGGGGATGCGCTGCACGTTTA
CAGGCTCTCTGGAACAGCCTGCACATGCGACGATTCCCGGAGGTTTTGATTATAAGGAATATCTTTACTCTCAGCAGATT
CACTGGTTATTTTCCGTGACTTCCATTGAGCAGTGTGAAAAATCCAAACAGCCGCTGTTTAAACTGCTGAACTTCAGAAA
AAATTTGATTTCAATCATTCGGAATCACGTACCTGAATCTTCCGCCGGAATTGTTGAAGCGCTGACCTTAGGTGAAAGAT
TTTCTATAGAGGACGATATACTGAGTGCATATCAAAATTTGGGAGTCGTTCATTTAATGGCGATTTCCGGAATGCATGTC
GGTCTTATTACGGCGGGACTATTTTATGCTCTGATCAGAATCGGGCTGACAAGAGAAAAGGCGGGGATGTTGCTGCTGCT
GTTTTTGCCGGTGTATACGCTGCTGAGCGGTGCCGCCCCATCCGTATTGCGCGCATCCCTCATGCTGGGATTTTATATCG
CCGGAACTCTTGTTAAACGCGGCATTCATTCCTCTGCTGCATTGTCTCTGTCTTATCTGCTGCTCCTGCTGTTTAATCCT
TACTTCCTTTGGCAGGCGGGCTTCCAGCTTTCCTTTGCGGTAAGCGCCTCTTTAATTCTGTCATCCTCCATTTTAAAGAA
AGCGGGGAAAAGCAGACTTGCCGGGCTTGCGATGGCCTCATTCATTGCAGAGCTCAGCTCACTTCCGTTTCTTCTCTATC
ATTTTCAGCAAATTTCACTTGTCAGTTTTCCGATGAACATGGTGATGGTGCCATTTTATACGTTATTTGTCATTCCGGTT
TCTGTCATCGGCTTCCTTCTTCTTTTGCTTTCAAGGCAGATGGGAGAATGTTTGTTTGATATGTTTGACCTTGTGATGAA
GCCTGTGCATGATTTCATTACATATGCGGCATCCGTTGATTTATTTACTATGATTGTGTCAAAGCCTGACTTTCTTTCCC
TTCTTCTGCTTGCGGTTTCCGTTTTTACGCTTTTTGCGGCTTTGGAAAAGGGAGGTTTTTTAAAACTCAGGAAATCGGCT
CTTTTTTTCTGCGCGGTTTTGGCTTATTTAATATGCCGTCCGTATTTCAGTCCATGGGGAGAAGCGGATATGCTTGATAT
CGGGCAGGGAGACTCGCTGTTTATAAGCGCGCCATACCGCAAAGGGACCGTAATGGTTGATACAGGGGGAGTGATTGCTT
ATCCCGGAGAATCATGGAAAGAAAAACGCCACCCGTATTCTATCGGCGAGAAGGTTTTGATTCCGTTTTTAAACGGAAAA
GGGGTGAAAAAGCTGGATGCGCTGTTTTTAACCCATGCGGATCAGGATCACATCGGAGAAGCCGGAGTGTTAATCAAAAA
TCATAGAGTCAAACGGTTAATTGTCCCCGTGGGATTCGTAAAAGAACCGAAGGATCAGAACATATTAAAAATGGCGAAAG
AAAACAACATTCCCGTTGCCGAAGCAAAGCGGGGCGACACCATTACAGCGGGTGATCTTCAGTTTCAGGTGCTGTCTCCG
GAGTCATCTGACGGAAAGAGTAAAAATGATTCATCACTGGTGCTTTGGACGGTTTTAGGCGGAGTGAGCTGGCTTTTGAC
GGGAGATTTAGAATCGGACGGCGAAACAGAAGTGCTGAAAACGTATCCGAAACTGAAGGCTGATATATTGAAGGCGGGTC
ATCACGGCAGCAAAAGCTCAACGAGTGAAGCCTTTTTGAAACAGCTTCAGCCGGAAGCAGCGCTGATTTCAGCAGGAAAA
GAGAATCGATACCATCATCCGCATGAAGAAGTGCTGGATCGTTTGAAGGCGTACTCTGTCAATGTGCTTCGCACCGATAT
CAGCGGAACGATTCAATACAGATTTGAAAAAGGCGCCGGAACGTTTTCCGTCTTCCCTCCATATGATATAGAAGAAACCA
GGGCGCAAGAAGTAAAAAAGACTGCCGATTGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (208-469)

• Domain of unknown function (DUF4131) (DUF4131) (25-171)

• Metallo-beta-lactamase superfamily (Lactamase_B) (508-719)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	56.088	98.595	0.553