Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   MWM12_RS01395 Genome accession   NZ_AP025603
Coordinates   246996..248000 (-) Length   334 a.a.
NCBI ID   WP_244341218.1    Uniprot ID   -
Organism   Thermus thermophilus strain SNM1-7     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 241996..253000
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MWM12_RS01360 (TthSNM17_02610) hisG 242468..243088 (+) 621 WP_244341209.1 ATP phosphoribosyltransferase -
  MWM12_RS01365 (TthSNM17_02620) trmH 243085..243669 (+) 585 WP_244341211.1 tRNA (guanosine(18)-2'-O)-methyltransferase TrmH -
  MWM12_RS01370 (TthSNM17_02630) - 243659..243898 (-) 240 WP_008630920.1 hypothetical protein -
  MWM12_RS01375 (TthSNM17_02640) - 243900..244088 (-) 189 WP_038034982.1 hypothetical protein -
  MWM12_RS01380 (TthSNM17_02650) - 244078..245034 (-) 957 WP_244341213.1 branched-chain amino acid transaminase -
  MWM12_RS01385 (TthSNM17_02660) - 245021..245974 (-) 954 WP_244341215.1 hydrogen peroxide-inducible genes activator -
  MWM12_RS01390 (TthSNM17_02670) - 246084..246992 (+) 909 WP_244341216.1 manganese catalase family protein -
  MWM12_RS01395 (TthSNM17_02680) dprA 246996..248000 (-) 1005 WP_244341218.1 DNA-processing protein DprA Machinery gene
  MWM12_RS01400 (TthSNM17_02690) era 248085..248990 (+) 906 WP_008630929.1 GTPase Era -
  MWM12_RS01405 (TthSNM17_02700) - 249035..249922 (+) 888 WP_011174227.1 acyltransferase -
  MWM12_RS01415 (TthSNM17_02710) - 250118..251293 (-) 1176 WP_244341220.1 site-specific integrase -
  MWM12_RS12605 - 251293..251424 (-) 132 WP_015716574.1 hypothetical protein -
  MWM12_RS01420 (TthSNM17_02720) - 251414..251593 (-) 180 WP_015716575.1 helix-turn-helix domain-containing protein -
  MWM12_RS01425 (TthSNM17_02730) - 252039..252242 (-) 204 WP_244341222.1 hypothetical protein -
  MWM12_RS01430 (TthSNM17_02740) - 252239..252475 (-) 237 WP_124104509.1 hypothetical protein -
  MWM12_RS01435 (TthSNM17_02750) - 252489..252779 (-) 291 WP_244341225.1 hypothetical protein -

Sequence

Protein


Download         Length: 334 a.a.        Molecular weight: 36297.21 Da        Isoelectric Point: 6.8892

>NTDB_id=92975 MWM12_RS01395 WP_244341218.1 246996..248000(-) (dprA) [Thermus thermophilus strain SNM1-7]
MDPLALAFLPGIGPKRLLEVLKAEDPLGFLRERFPEAWRHLPEAEAQAERERRRAEALGVRLLGLWEEGFPEGLKALPQP
PTHLYLKGELPPEREAVALVGTRRASPWALAFARRLARELSEAGLWVVSGLARGIDREAHLGALEAGGRTLGVLGSALDR
VYPPENRPLAQRMDLLSEFPFGTGPKPEFFPRRNRLIAGLCRAVVVVEAPLDSGALITARHALELGKEVLAVPGRPMDER
SLGANRLIQDGAYPVLSAEDVLSYLGMSARPKPLPGLSPEEEALYALLQEKKEALPEALAMALGIPPERVLSLLTLLELK
GLARALPGGRYGPG

Nucleotide


Download         Length: 1005 bp        

>NTDB_id=92975 MWM12_RS01395 WP_244341218.1 246996..248000(-) (dprA) [Thermus thermophilus strain SNM1-7]
GTGGACCCCTTGGCCCTCGCCTTCCTCCCGGGCATCGGCCCCAAGCGGCTTCTGGAGGTCCTAAAGGCGGAGGACCCTCT
GGGCTTCCTGCGGGAGCGCTTCCCCGAGGCCTGGCGGCACCTCCCCGAGGCCGAGGCCCAGGCGGAAAGGGAGAGGCGGC
GCGCCGAGGCCCTAGGGGTGCGCCTCCTGGGCCTCTGGGAGGAGGGCTTCCCCGAGGGGCTGAAGGCGCTTCCCCAGCCG
CCCACCCACCTCTACCTGAAGGGGGAGCTTCCCCCGGAAAGGGAGGCGGTGGCCCTCGTGGGCACGCGCCGGGCCTCCCC
TTGGGCCCTGGCCTTTGCCAGGAGGCTCGCCCGGGAGCTTTCCGAGGCCGGGCTCTGGGTGGTCTCGGGCCTCGCCCGGG
GCATAGACCGGGAGGCCCACCTCGGGGCCCTCGAGGCCGGGGGGCGCACCCTGGGCGTCTTGGGAAGCGCCCTGGACCGG
GTCTACCCCCCGGAAAACCGCCCTTTGGCCCAACGGATGGACCTCCTCTCCGAGTTCCCCTTCGGCACCGGGCCCAAGCC
CGAGTTCTTTCCCCGGCGGAACCGCCTCATCGCCGGGCTTTGCCGGGCGGTGGTCGTGGTGGAGGCCCCCCTGGACTCCG
GGGCCCTCATCACCGCCCGCCACGCCCTGGAGCTCGGCAAGGAGGTGCTGGCCGTGCCCGGAAGGCCCATGGACGAGCGT
TCCCTGGGGGCGAACCGCCTCATCCAGGACGGGGCCTACCCGGTGCTCTCCGCCGAGGATGTCCTCTCCTATCTGGGAAT
GTCCGCAAGGCCCAAGCCCCTCCCGGGCCTCTCCCCGGAGGAGGAGGCCCTTTACGCCCTCCTGCAGGAAAAGAAGGAGG
CGCTCCCCGAGGCCCTGGCCATGGCCCTGGGGATCCCCCCGGAGCGGGTGCTCTCCCTCCTCACCCTTTTGGAGCTAAAG
GGCCTGGCCCGGGCCCTCCCGGGAGGGCGCTACGGGCCAGGCTAA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(269-329)

DNA recombination-mediator protein A (DNA_processg_A)

(56-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Thermus thermophilus HB27

99.401

100

0.994
  dprA Vibrio campbellii strain DS40M4

38.547

100

0.413
  dprA Vibrio cholerae strain A1552

37.535

100

0.401
  dprA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

45.392

87.725

0.398

Multiple sequence alignment